Search: authors:"Myoung Sup Shim"

A DNA replication‐related element downstream from the initiation site of Drosophila selenophosphate synthetase 2 gene is essential for its transcription

Selenophosphate synthetase catalyzes the synthesis of selenophosphate which is a selenium donor for Sec biosynthesis. In Drosophila melanogaster, there are two types of selenophosphate synthetases designated dSPS1 and dSPS2, where dSPS2 is a selenoprotein. The mechanism of gene expression of dSPS2 as well as other selenoproteins in Drosophila has not been elucidated. Herein, we...