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Of genes and microbes: solving the intricacies in host genomes

D receptor. COMPLIANCE WITH ETHICS GUIDELINES Jun Wang, Liang Chen, Na Zhao, Xizhan Xu, Yakun Xu and Baoli Zhu declare that they have no conflict of interest. OPEN ACCESS This article is

Why employees stay: the roles of psychological ownership, territoriality and work relationship closeness in affecting employee turnover intention

Drawing on a tripartite perspective on attitudes, this study examines the influence of psychological ownership and territoriality on turnover intention, as well as the moderating role of work relationship closeness on the relationship between territoriality and turnover intention. Analyses of longitudinal data collected from 341 employees in three Chinese automobile manufacturing...

A novel method for the detection of R-peaks in ECG based on K-Nearest Neighbors and Particle Swarm Optimization

Cardiovascular diseases are associated with high morbidity and mortality. However, it is still a challenge to diagnose them accurately and efficiently. Electrocardiogram (ECG), a bioelectrical signal of the heart, provides crucial information about the dynamical functions of the heart, playing an important role in cardiac diagnosis. As the QRS complex in ECG is associated with...

A fast and robust interpolation filter for airborne lidar point clouds

A fast and robust interpolation filter based on finite difference TPS has been proposed in this paper. The proposed method employs discrete cosine transform to efficiently solve the linear system of TPS equations in case of gridded data, and by a pre-defined weight function with respect to simulation residuals to reduce the effect of outliers and misclassified non-ground points...

Use of fish species from different trophic levels to control algae and water quality: An enclosure experiment in eutrophic area of Xiaojiang River

The effects of stocking both filter-feeding fish and piscivorous fish were compared to the effects of stocking only filter-feeding fish for suppressing algal blooms and improving water quality in the impoundment area of Xiaojiang River where catfish were dominant. Using only filter-feeding fish for algal suppression and water quality control was more effective in the short-term...

Effect of Dietary Types on Feed Intakes, Growth Performance and Economic Benefit in Tibetan sheep and Yaks on the Qinghai-Tibet Plateau during Cold Season

Pastoralists on the Tibetan alpine rangeland suffered great economic loss in cold season, due to serious live-weight loss of domestic livestock under traditional grazing management. This study aimed to evaluate the effect of dietary types (crude protein levels) on feed intakes, growth performance and economic returns of local Tibetan sheep and yaks during cold season. Twenty-four...

Differences in the Epidemiology of Childhood Infections with Avian Influenza A H7N9 and H5N1 Viruses

The difference between childhood infections with avian influenza viruses A(H5N1) and A(H7N9) remains an unresolved but critically important question. We compared the epidemiological characteristics of 244 H5N1 and 41 H7N9 childhood cases (<15 years old), as well as the childhood cluster cases of the two viruses. Our findings revealed a higher proportion of H5N1 than H7N9...

Analysis on Soil Seed Bank Diversity Characteristics and Its Relation with Soil Physical and Chemical Properties after Substrate Addition

Aims Considered as an essential measure in the application of soil seed bank (SSB) projects, the mixing of substrate and surface soil can effectively improve soil condition. This research is aimed at exploring the diversity characteristics of SSBs and the relationships between SSBs and soil properties. Methods Canonical correspondence analysis (CCA) was adopted to describe the...

Changes and Relationships of Climatic and Hydrological Droughts in the Jialing River Basin, China

The comprehensive assessment of climatic and hydrological droughts in terms of their temporal and spatial evolutions is very important for water resources management and social development in the basin scale. To study the spatial and temporal changes of climatic and hydrological droughts and the relationships between them, the SPEI and SDI are adopted to assess the changes and...

Noninvasive versus invasive mechanical ventilation for immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis

Background To determine the effects of noninvasive mechanical ventilation (NIV) compared with invasive mechanical ventilation (IMV) as the initial mechanical ventilation on clinical outcomes when used for treatment of acute respiratory failure (ARF) in immunocompromised patients. Methods We searched PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), the...

Mfn2 Affects Embryo Development via Mitochondrial Dysfunction and Apoptosis

Background Growth factors, energy sources, and mitochondrial function strongly affect embryo growth and development in vitro. The biological role and prospective significance of the mitofusin gene Mfn2 in the development of preimplantation embryos remain poorly understood. Our goal is to profile the role of Mfn2 in mouse embryos and determine the underlying mechanism of Mfn2...

MutS HOMOLOG1 silencing mediates ORF220 substoichiometric shifting and causes male sterility in Brassica juncea

Cytoplasmic male sterility (CMS) has consistently been associated with the expression of mitochondrial open reading frames (ORFs) that arise from genomic rearrangements. Spontaneous fertility reversion in CMS has been observed in several cases, but a clear understanding of fertility reversion controlled by nuclear genetic influences has been lacking. Here, we identified...

Persistently high prevalence of primary resistance and multidrug resistance of tuberculosis in Heilongjiang Province, China

Background The spread of multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M. tuberculosis) strains has been a big challenge to the TB control and prevention in China. Knowledge about patterns of drug resistance in TB high-burden areas of China is crucial to develop appropriate control strategies. We conducted a comprehensive investigation of the resistance...

Comparative Epidemiology of Human Infections with Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome Coronaviruses among Healthcare Personnel

The largest nosocomial outbreak of Middle East respiratory syndrome (MERS) occurred in South Korea in 2015. Health Care Personnel (HCP) are at high risk of acquiring MERS-Coronavirus (MERS-CoV) infections, similar to the severe acute respiratory syndrome (SARS)-Coronavirus (SARS-CoV) infections first identified in 2003. This study described the similarities and differences in...

Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2

Aim IL-1β was considered as an important inflammatory cytokine in diabetic cardiovascular complications. DCM is one of the major manifestations of diabetic cardiovascular complications whose specific mechanisms are still unclear. In this study, we investigated the role of IL-1β in myocytes apoptosis in DCM. Methods In the in vitro study, high- glucose medium and/or IL-1β were...

Cell fusion between gastric epithelial cells and mesenchymal stem cells results in epithelial-to-mesenchymal transition and malignant transformation

Background The discovery of cancer stem cells and tumor heterogeneity prompted the exploration of additional mechanisms aside from genetic mutations for carcinogenesis and cancer progression. The aim of the present study was to investigate the effect of cell fusion between mesenchymal stem cells and the gastric epithelial cells in tumorigenesis. Methods Cell fusion between cord...