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Search: authors:"Naiara Perurena"

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EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

Background Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells. Emerging evidence indicates that EPCR also plays a role in breast stemness and human tumorigenesis. Yet, its contribution to breast cancer progression and metastasis has not been elucidated. Methods ...