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Numerical simulation study on effectiveness of shielding structure on ultrasonic transmission tomography

Research Funds for the Central Universities (3102017OQD028). About the authors Nan Li received his B.S. and Ph.D. degree in 2004 and 2010, respectively, from Xidian University. He has worked as an associate

Defect-related luminescent bur-like hydroxyapatite microspheres induced apoptosis of MC3T3-E1 cells by lysosomal and mitochondrial pathways

When orthopedic joints coated by hydroxyapatite (HA) were implanted in the human body, they release wear debris into the surrounding tissues. The generation and accumulation of wear particles will induce aseptic loosening. However, the potential bioeffect and mechanism of HA-coated orthopedic implants on bone cells are poorly understood. In this study, defect-related luminescent...

Combined epidural-general anesthesia was associated with lower risk of postoperative complications in patients undergoing open abdominal surgery for pheochromocytoma: A retrospective cohort study

: Nan Li. Conceptualization: Nan Li, Hao Kong, Shuang-Ling Li, Dong-Xin Wang. Formal analysis: Nan Li, Hao Kong, Sai-Nan Zhu, Dong-Xin Wang. Funding acquisition: Nan Li. Investigation: Nan Li, Hao Kong ... . Methodology: Sai-Nan Zhu, Dong-Xin Wang. Resources: Dong-Xin Wang. Software: Sai-Nan Zhu. Supervision: Shuang-Ling Li, Dong-Xin Wang. Validation: Hao Kong, Sai-Nan Zhu. Writing ± original draft: Nan Li

One-Pot Synthesis of Cu2ZnSnSe4 Nanoplates and their Visible-Light-Driven Photocatalytic Activity

A SeO2 ethanol solution as the facile precursor has been used for the preparation of quaternary Cu2ZnSnSe4 (CZTSe) nanoplates. Monodispersed single-phase CZTSe nanoplates have been prepared successfully by a facile one-pot thermal chemical method. The as-prepared CZTSe nanoplates show uniform morphology with a bandgap of ~ 1.4 eV. As a proof of concept, the CZTSe nanoplates have...

IL-13 receptors as possible therapeutic targets in diffuse intrinsic pontine glioma

selection for sequencing experiments We obtained tumor tissues from sixteen (16) new DIPG samples for exome sequencing. Eight (8) samples were provided by Dr. Xiao-Nan Li of Texas Children's Cancer and ... Hulleman at Vrije Universiteit University Medical Center. We also obtained tumor tissues from seventeen (17) new DIPG samples for transcriptome sequencing. Nine (8) samples were provided by Dr. Xiao-Nan Li

The earlier, the better: the effects of different administration timepoints of sorafenib in suppressing the carcinogenesis of VEGF in rats

Purpose To investigate the optimal starting time point of sorafenib therapy in suppressing the tumor-promoting effects of VEGF up-regulation, which is frequently found after local therapy in clinical practice. Methods VEGF was intravenously injected to imitate the evaluated expression after local tumor therapy, such as TACE. A total of 40 SD rats bearing hepatic tumors were...

A Method about the Propagation of Faults in Network

The study of network has been developed for several years. The research usually focuses on the attributes of the network, including the heterogeneity [1], the topology [2] [3] and the communities [4][5] of the network. About the propagation dynamics, reference [6][7] laid emphasis on the mathematical analysis of the propagation of networks. Although these researches are important...

Dynamic Probing of Microstructure Evolution in Nanostructured Materials

macroscopic level. The article by Liu et al., ‘‘In-situ TEM Nanoindentation Studies on Stress-Induced Nan Li is the guest editor for the Nanomechanical Materials Behavior Committee of the TMS Materials

Explorations of two empirical formulas for fermion masses

Two empirical formulas for the lepton and quark masses (i.e. Kartavtsev’s extended Koide formulas), \(K_l=(\sum _l m_l)/(\sum _l\sqrt{m_l})^2=2/3\) and \(K_q=(\sum _q m_q)/(\sum _q\sqrt{m_q})^2=2/3\), are explored in this paper. For the lepton sector, we show that \(K_l=2/3\), only if the uncertainty of the tauon mass is relaxed to about \(2\sigma \) confidence level, and the...

Plasma from patients with anti-glomerular basement membrane disease could recognize microbial peptides

Infection has long been suspected as a trigger of autoimmune diseases, and molecular mimicry mechanism was hypothesized in this study. Microbe originated peptides were searched from the Uniprot database based on a previous defined critical amino acid motif within α3129−150, isoleucine137, tryptophan140, glycine142, phenylalanine 143 and phenylalanine 145. 23826 microbial peptides...

Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice

Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease. In this study, we generated MARV virus-like particles (VLPs) by co-expressing the glycoprotein (GP) and matrix protein (VP40) using the...

An analytical investigation on the wrinkling of aluminium alloys during stamping using macro-scale structural tooling surfaces

Structural surface texturing is believed to be a promising approach to modify tribological and thermal performances of tooling for sheet-stamping processes. However, a fundamental study on the surface-texturing design and resulting material deformation is currently lacking. In this paper, an advanced analytical buckling model specifically for the utilisation of textured tools at...

Early Postnatal Exposure to Cigarette Smoke Leads to Later Airway Inflammation in Asthmatic Mice

Background and objective Asthma is one of the most common airway inflammatory diseases. In most cases, asthma development is related to ubiquitous harmful environmental exposure factors in early-life. Previous studies have indicated that smoking can promote asthma development and increase the difficulty of asthma control. The aim of this study was to determine the effects of...

Dark energy and normalization of the cosmological wave function

Dark energy is investigated from the perspective of quantum cosmology. It is found that, together with an appropriate normal ordering factor q, only when there is dark energy can the cosmological wave function be normalized. This interesting observation may require further attention.

Analysis of the Negative-SET Behaviors in Cu/ZrO2/Pt Devices

Metal oxide-based electrochemical metallization memory (ECM) shows promising performance for next generation non-volatile memory. The negative-SET behavior has been observed in various oxide-based ECM devices. But the underlying mechanism of this behavior remains unaddressed and the role of the metal cation and oxygen vacancy in this behavior is unclear. In this work, we have...

Analysis of the Negative-SET Behaviors in Cu/ZrO2/Pt Devices

Metal oxide-based electrochemical metallization memory (ECM) shows promising performance for next generation non-volatile memory. The negative-SET behavior has been observed in various oxide-based ECM devices. But the underlying mechanism of this behavior remains unaddressed and the role of the metal cation and oxygen vacancy in this behavior is unclear. In this work, we have...

An investigation of involute and lead deflection in hot precision forging of gears

A theoretical model is presented in the paper for predicting involute profile deflection in hot precision forging of gears. This model is a function of a number of material and processing parameters, including the thermal expansion of the die, thermal contraction of workpiece, elastic expansion of the die during forging, and workpiece recovery after ejection. To improve the...

Disrupted-in-schizophrenia1 (DISC1) L100P mutation alters synaptic transmission and plasticity in the hippocampus and causes recognition memory deficits

Disrupted-in-schizophrenia 1(DISC1) is a promising candidate susceptibility gene for a spectrum of psychiatric illnesses that share cognitive impairments in common, including schizophrenia, bipolar disorder and major depression. Here we report that DISC1 L100P homozygous mutant shows normal anxiety- and depression-like behavior, but impaired object recognition which is prevented...

Unified constitutive modelling for two-phase lamellar titanium alloys at hot forming conditions

In this paper, a set of mechanism based unified viscoplastic constitutive equations have been established for two-phase titanium alloys with initial lamellar microstructure, which models the softening mechanisms of the alloys in hot forming conditions. The dislocation density, rotation and globularization of lamellar α-phase and their effects on flow behaviour can also be...

An exploration of the black hole entropy via the Weyl tensor

The role of the Weyl tensor \(C_{\mu \nu \lambda \rho }\) in black hole thermodynamics is explored by looking at the relation between the scalar invariant \(C_{\mu \nu \lambda \rho }C^{\mu \nu \lambda \rho }\) and the entropy of n-dimensional static black holes. It is found that this invariant can be identified as the entropy density of the gravitational fields for classical 5...