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145 papers found.
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Tuned and non-Higgsable U(1)s in F-theory

We study the tuning of U(1) gauge fields in F-theory models on a base of general dimension. We construct a formula that computes the change in Weierstrass moduli when such a U(1) is tuned, based on the Morrison-Park form of a Weierstrass model with an additional rational section. Using this formula, we propose the form of “minimal tuning” on any base, which corresponds to the case ...

Modified human glucagon-like peptide-1 (GLP-1) produced in E. coli has a long-acting therapeutic effect in type 2 diabetic mice

abbreviations in alphabetical order. (XLSX) Author Contributions Conceptualization: Dehu Liu. Data curation: Fangfang Xu, Nan Wang, Gangqiang Li. Formal analysis: Fangfang Xu, Kevin Yueju Wang, Nan Wang ... . Funding acquisition: Dehu Liu. Investigation: Dehu Liu. Methodology: Fangfang Xu, Nan Wang, Gangqiang Li. Resources: Nan Wang. Supervision: Kevin Yueju Wang. Writing ± original draft: Fangfang Xu, Kevin

Gaussian-binary restricted Boltzmann machines for modeling natural image statistics

sampling algorithms for training GRBMs and show that Contrastive Divergence performs better than training methods that use a persistent Markov chain. - Funding: Author Nan Wang was employed by Institut ... fuÈr Neuroinformatik, Ruhr- UniversitaÈt at Bochum at the time of the study and is now employed by Zalando SE. Zalando SE provided no financial support for the study. Nan Wang was supported by a

Transcriptomic analysis of the response of Pseudomonas fluorescens to epigallocatechin gallate by RNA-seq

Epigallocatechin gallate (EGCG) is a main constituent of green tea polyphenols that are widely used as food preservatives and are considered to be safe for consumption. However, the underlying antimicrobial mechanism of EGCG and the bacterial response to EGCG are not clearly understood. In the present study, a genome-wide transcriptional analysis of a typical spoilage bacterium, ...

The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

; MOI, multiplicity of infection; SCARB2, scavenger receptor class B member 2. COMPLIANCE WITH ETHICS GUIDELINES Xuyuan Zhang, Pan Yang, Nan Wang, Jialong Zhang, Jingyun Li, Hao Guo, Xiangyun Yin, Zihe

Expression of a fungal manganese peroxidase in Escherichia coli: a comparison between the soluble and refolded enzymes

Background Manganese peroxidase (MnP) from Irpex lacteus F17 has been shown to have a strong ability to degrade recalcitrant aromatic pollutants. In this study, a recombinant MnP from I. lacteus F17 was expressed in Escherichia coli Rosetta (DE3) in the form of inclusion bodies, which were refolded to achieve an active enzyme. Further, we optimized the in vitro refolding conditions ...

Bioactivity of a modified human Glucagon-like peptide-1

Diabetes has become the third largest cause of death in humans worldwide. Therefore, effective treatment for this disease remains a critical issue. Glucagon-like peptide-1 (GLP-1) plays an important role in glucose homeostasis, and therefore represents a promising candidate to use for the treatment of diabetes. Native GLP-1, however, is quickly degraded in in the circulatory ...

Authenticity and Relationship Satisfaction: Two Distinct Ways of Directing Power to Self-Esteem

Possessing power contributes to high self-esteem, but how power enhances self-esteem is still unknown. As power is associated with both self-oriented goals and social-responsibility goals, we proposed that power predicts self-esteem through two positive personal and interpersonal results: authenticity and relationship satisfaction. Three studies were carried out with a total of 505 ...

Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation

Luman (also known as LZIP or CREB3) is a transcription factor and a member of the cAMP responsive element-binding (CREB) family proteins. Although Luman has been detected in apoptotic granulosa cells and disorganized atretic bodies, the physiological function of Luman in follicular development has not been reported. Our objective is to determine the role of Luman in ...

Estimation of basal metabolic rate in Chinese: are the current prediction equations applicable?

Background Measurement of basal metabolic rate (BMR) is suggested as a tool to estimate energy requirements. Therefore, BMR prediction equations have been developed in multiple populations because indirect calorimetry is not always feasible. However, there is a paucity of data on BMR measured in overweight and obese adults living in Asia and equations developed for this group of ...

Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta-analysis

Chen 0 Shu‑Nan Wang Jian‑min Wang 0 0 Research Institute of Surgery, Daping Hospital, Third Military Medical University , Chongqing 400042 , People's Republic of China Background: Sepsis is one of the

Effects of Acute Systemic Hypoxia and Hypercapnia on Brain Damage in a Rat Model of Hypoxia-Ischemia

Therapeutic hypercapnia has the potential for neuroprotection after global cerebral ischemia. Here we further investigated the effects of different degrees of acute systemic hypoxia in combination with hypercapnia on brain damage in a rat model of hypoxia and ischemia. Adult wistar rats underwent unilateral common carotid artery (CCA) ligation for 60 min followed by ventilation ...

A Monte Carlo exploration of threefold base geometries for 4d F-theory vacua

We use Monte Carlo methods to explore the set of toric threefold bases that support elliptic Calabi-Yau fourfolds for F-theory compactifications to four dimensions, and study the distribution of geometrically non-Higgsable gauge groups, matter, and quiver structure. We estimate the number of distinct threefold bases in the connected set studied to be ∼ 1048. The distribution of ...

Genetic effects and genotype × environment interactions govern seed oil content in Brassica napus L.

Background As seed oil content (OC) is a key measure of rapeseed quality, better understanding the genetic basis of OC would greatly facilitate the breeding of high-oil cultivars. Here, we investigated the components of genetic effects and genotype × environment interactions (GE) that govern OC using a full diallel set of nine parents, which represented a wide range of the Chinese ...

A comparative study of k-spectrum-based error correction methods for next-generation sequencing data analysis

Background Innumerable opportunities for new genomic research have been stimulated by advancement in high-throughput next-generation sequencing (NGS). However, the pitfall of NGS data abundance is the complication of distinction between true biological variants and sequence error alterations during downstream analysis. Many error correction methods have been developed to correct ...

The F-theory geometry with most flux vacua

Applying the Ashok-Denef-Douglas estimation method to elliptic Calabi-Yau fourfolds suggests that a single elliptic fourfold \( {\mathrm{\mathcal{M}}}_{\max } \) gives rise to \( \mathcal{O}\left({10}^{272,000}\right) \) F-theory flux vacua, and that the sum total of the numbers of flux vacua from all other F-theory geometries is suppressed by a relative factor of \( ...

Genome-wide identification of soybean WRKY transcription factors in response to salt stress

Members of the large family of WRKY transcription factors are involved in a wide range of developmental and physiological processes, most particularly in the plant response to biotic and abiotic stress. Here, an analysis of the soybean genome sequence allowed the identification of the full complement of 188 soybean WRKY genes. Phylogenetic analysis revealed that soybean WRKY genes ...

Generalized Cartan Calculus in general dimension

We develop the generalized Cartan Calculus for the groups \( G=\mathrm{S}\mathrm{L}\left(2,\mathrm{\mathbb{R}}\right)\times {\mathrm{\mathbb{R}}}^{+},\mathrm{S}\mathrm{L}\left(5,\mathrm{\mathbb{R}}\right) \) and SO(5, 5). They are the underlying algebraic structures of d = 9, 7, 6 exceptional field theory, respectively. These algebraic identities are needed for the “tensor ...

Nonlinear dynamics of a marine phytoplankton-zooplankton system

In the paper, the nonlinear dynamics of a marine phytoplankton-zooplankton system is discussed in detail. The aim is to deeply expound how to use the dynamical laws of marine ecological system to perfectly reflect the operating rules of marine ecosystems. The mathematical work has been pursuing the investigation of some conditions for the local and global stability of the ...