Search: authors:"Nathan A. Gillespie"

Early expressions of psychopathology and risk associated with trans-diagnostic transition to mood and psychotic disorders in adolescents and young adults

technologies. Author Contributions Conceptualization: Jan Scott, Nicholas Martin, Nathan A. Gillespie, Ian B. Hickie. Formal analysis: Jan Scott, Jacob J. Crouse, Nicholas Ho. Funding acquisition: Nicholas ... Martin, Nathan A. Gillespie. Investigation: Richard Parker, John McGrath, Nathan A. Gillespie, Sarah Medland. Methodology: Jan Scott, Jacob J. Crouse, Nicholas Ho, Ian B. Hickie. Project administration

A Twin Study of Early-Childhood Asthma in Puerto Ricans

Background The relative contributions of genetics and environment to asthma in Hispanics or to asthma in children younger than 3 years are not well understood. Objective To examine the relative contributions of genetics and environment to early-childhood asthma by performing a longitudinal twin study of asthma in Puerto Rican children ≤3 years old. Methods 678 twin infants from...

Head Motion and Inattention/Hyperactivity Share Common Genetic Influences: Implications for fMRI Studies of ADHD

Head motion (HM) is a well known confound in analyses of functional MRI (fMRI) data. Neuroimaging researchers therefore typically treat HM as a nuisance covariate in their analyses. Even so, it is possible that HM shares a common genetic influence with the trait of interest. Here we investigate the extent to which this relationship is due to shared genetic factors, using HM...

Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes

Hair cortisol concentration (HCC) is a promising measure of long-term hypothalamus-pituitary-adrenal (HPA) axis activity. Previous research has suggested an association between HCC and psychological variables, and initial studies of inter-individual variance in HCC have implicated genetic factors. However, whether HCC and psychological variables share genetic risk factors remains...

Author Correction: GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal effect of schizophrenia liability

Gelernter , Dorret I. Boomsma, Nicholas G. Martin, Stuart MacGregor , John R. B. Perry, Abraham A. Palmer , Danielle Posthuma , Marcus R. Munafò , Nathan A. Gillespie, Eske M. Derks and

Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes

, Brien P Riley, Nathan A Gillespie & John M HettemaDepartments of Biomedical Informatics and Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USAAn-Yuan Guo & Zhongming ZhaoDepartment ... • Google ScholarSearch for Brien P Riley in:Nature Research journals • PubMed • Google ScholarSearch for Nathan A Gillespie in:Nature Research journals • PubMed • Google ScholarSearch for Carol A Prescott

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

The volume of the lateral ventricles (LV) increases with age and their abnormal enlargement is a key feature of several neurological and psychiatric diseases. Although lateral ventricular volume is heritable, a comprehensive investigation of its genetic determinants is lacking. In this meta-analysis of genome-wide association studies of 23,533 healthy middle-aged to elderly...

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16–102) and find 148 genome-wide significant independent loci (P < 5 × 10−8) associated with general cognitive function. Within the novel...