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Search: authors:"Nele A. Haelterman"

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FlyVar: a database for genetic variation in Drosophila melanogaster

. Nele , A. , Haelterman , L.J. , Li , Y. et al. ( 2014 ) Large-scale identification of chemically induced mutations in Drosophila melanogaster . Genome Res ., 24 , 1707 - 1718 . 10. Chen , D. , Ahlford

Impaired Mitochondrial Energy Production Causes Light-Induced Photoreceptor Degeneration Independent of Oxidative Stress

Two insults often underlie a variety of eye diseases including glaucoma, optic atrophy, and retinal degeneration—defects in mitochondrial function and aberrant Rhodopsin trafficking. Although mitochondrial defects are often associated with oxidative stress, they have not been linked to Rhodopsin trafficking. In an unbiased forward genetic screen designed to isolate mutations that...