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Search: authors:"Nicolas T. Chartier"

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CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness

The homeobox transcription factor CDX2 plays a crucial role in intestinal cell fate specification, both during normal development and in tumorigenic processes involving intestinal reprogramming. The CDX2 regulatory network is intricate, but it has not yet been fully uncovered. Through genome-wide screening of a 3D culture system, the RNA-binding protein MEX3A was identified as ...