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Search: authors:"Nienke S. van Ditzhuijzen"

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Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine

Contributions Conceptualization: Nienke S. van Ditzhuijzen, Mieke van den Heuvel, Oana Sorop, Evelyn Regar. Data curation: Nienke S. van Ditzhuijzen, Oana Sorop, Jurgen Ligthart, Karen Witberg, Gijs van Soest ... , Dirk-Jan Duncker, Evelyn Regar, Heleen M. M. van Beusekom. Formal analysis: Nienke S. van Ditzhuijzen, Mie Kurata, Magdalena Murawska, Brett Bouma, Martin Villiger, Gijs van Soest, Evelyn Regar

OCT-measured plaque free wall angle is indicative for plaque burden: overcoming the main limitation of OCT?

The aim of this study was to investigate the relationship between the plaque free wall (PFW) measured by optical coherence tomography (OCT) and the plaque burden (PB) measured by intravascular ultrasound (IVUS). We hypothesize that measurement of the PFW could help to estimate the PB, thereby overcoming the limited ability of OCT to visualize the external elastic membrane in the...

Influence of the Accuracy of Angiography-Based Reconstructions on Velocity and Wall Shear Stress Computations in Coronary Bifurcations: A Phantom Study

Introduction Wall shear stress (WSS) plays a key role in the onset and progression of atherosclerosis in human coronary arteries. Especially sites with low and oscillating WSS near bifurcations have a higher propensity to develop atherosclerosis. WSS computations in coronary bifurcations can be performed in angiography-based 3D reconstructions. It is essential to evaluate how...

Early Systemic Microvascular Damage in Pigs with Atherogenic Diabetes Mellitus Coincides with Renal Angiopoietin Dysbalance

Background Diabetes mellitus (DM) is associated with a range of microvascular complications including diabetic nephropathy (DN). Microvascular abnormalities in the kidneys are common histopathologic findings in DN, which represent one manifestation of ongoing systemic microvascular damage. Recently, sidestream dark-field (SDF) imaging has emerged as a noninvasive tool that...