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Current issues in postmortem imaging of perinatal and forensic childhood deaths

Perinatal autopsy practice is undergoing a state of change with the introduction of evidence-based cross-sectional imaging, driven primarily by parental choice. In particular, the introduction of post mortem magnetic resonance imaging (PMMR) has helped to advance less-invasive perinatal autopsy in the United Kingdom (UK) and Europe. However, there are limitations to PMMR and...

Think it through first: questions to consider in writing a successful grant application

Owen J. Arthurs Outline approach 0 ) Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust , Great Ormond Street, London, UK WC1N 3JH Writing a good grant

Postmortem cardiac imaging in fetuses and children

Fetal and pediatric cardiac autopsies have a crucial role in the counseling of parents with regard to both the cause of death of their child and the implications of such findings for future pregnancies, as well as for quality assurance of antenatal screening programs and antemortem diagnostic procedures. Postmortem imaging allows an opportunity to investigate the heart in situ...

Indications, advantages and limitations of perinatal postmortem imaging in clinical practice

Just as there is a range of paediatric imaging techniques available during life, a similar repertoire is available as part of the foetal and perinatal postmortem examination. In this article, we review the literature regarding the diagnostic utility of postmortem radiography, US, CT and MRI in this clinical setting. There is limited direct evidence on the diagnostic utility of...

Normal perinatal and paediatric postmortem magnetic resonance imaging appearances

As postmortem imaging becomes more widely used following perinatal and paediatric deaths, the correct interpretation of images becomes imperative, particularly given the increased use of postmortem magnetic resonance imaging. Many pathological processes may have similar appearances in life and following death. A thorough knowledge of normal postmortem changes is therefore...

Lung aeration on post-mortem magnetic resonance imaging is a useful marker of live birth versus stillbirth

Objective Aim of this study was to investigate whether lung assessment on post-mortem magnetic resonance imaging (PMMR) can reliably differentiate between live birth and stillbirth. Materials and methods We retrospectively assessed PMMR imaging features of a group of late foetal terminations following fetocide and stillbirths (without witnessed breathing) and early infant deaths...

Postmortem magnetic resonance appearances of congenital high airway obstruction syndrome

, determination of the anatomical level of the atresia/stenosis, and identification of associated abnormalities without the need for invasive autopsy. Acknowledgements Owen J. Arthurs is funded by an NIHR Clinician

Paediatric and perinatal postmortem imaging: the need for a subspecialty approach

delivery during the next few years. This may be achieved through the development of an International Paediatric Postmortem Imaging Network or other multiinstitutional collaborations. Acknowledgements Owen J ... . Arthurs is funded by an NIHR Clinician Scientist Fellow award, and Andrew M. Taylor is funded by an NIHR Senior Research Fellow award and by the Foundation Leducq. Neil J. Sebire is Neil J Sebire is funded

Diffusion-weighted perinatal postmortem magnetic resonance imaging as a marker of postmortem interval

timing and nature of the different changes in individual organ ADC values which occurs soon after death. Acknowledgements The scientific guarantor of this publication is Owen J. Arthurs. The authors of

Diagnostic accuracy of post-mortem MRI for thoracic abnormalities in fetuses and children

Objectives To compare the diagnostic accuracy of post-mortem magnetic resonance imaging (PMMR) specifically for non-cardiac thoracic pathology in fetuses and children, compared with conventional autopsy. Methods Institutional ethics approval and parental consent was obtained. A total of 400 unselected fetuses and children underwent PMMR before conventional autopsy, reported...

Malfunctioning central venous catheters in children: a diagnostic approach

Alex Barnacle Owen J. Arthurs Derek Roebuck Melanie P. Hiorns 0 ) Radiology Department, Great Ormond Street Hospital , Great Ormond Street, London WC1N 3JH, UK Central venous access is increasingly