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23 papers found.
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Determination of a high spatial resolution geopotential model using atomic clock comparisons

Recent technological advances in optical atomic clocks are opening new perspectives for the direct determination of geopotential differences between any two points at a centimeter-level accuracy in geoid height. However, so far detailed quantitative estimates of the possible improvement in geoid determination when adding such clock measurements to existing data are lacking. We...

Anagram Crossword Logic Puzzle

Mark J. P. Wolf South Milwaukee Wisconsin Most words in this crossword puzzle are anagrams of other words in the puzzle, such that definitions can refer to each other in such a way as to make the

Erratum to: Mobile source of high-energy single-cycle terahertz pulses

: Y. Petit CNRS, University Bordeaux , ICMCB, UPR 9048, 33600 Pessac , France 1 A. G. Stepanov (&) S. Henin Y. Petit L. Bonacina J. Kasparian J.-P. Wolf GAP-Biophotonics, Universite de Gene`ve , Chemin ... specified sensitivity at 1.06 lm [3], and this difference has been take into account in a following publication [7]. 1. A.G. Stepanov , S. Henin , Y. Petit , L. Bonacina , J. Kasparian , J.-P. Wolf, Appl

Elemental Crossword

Mark J. P. Wolf South Milwaukee 0 Wisconsin 0 0 63. Willow used for wickerwork 65. Mexican food 67. Like Chicago 68. A school of medicine 69. Dominant or recessive With a little bit of imagination

Word Worm Maze

Starting with the "A

A decision exercise to engage cancer patients and families in Deliberation about Medicare Coverage for advanced Cancer Care

Gregory P Samsa Steven P Wolf Lynn Howie Donald H Taylor Jr 0 0 Sanford School of Public Policy, Duke University , Box 90253, Durham, NC 27708 , USA Background: Concerns about unsustainable costs in the

Assisted reproductive technologies in rhesus macaques

The assisted reproductive technologies (ARTs) have been used in the production of rhesus monkey offspring at the Oregon National Primate Research Center (ONPRC) and that experience is summarized here. Additionally these technologies serve as a source of oocytes/embryos for monozygotic twinning, embryonic stem (ES) cell derivation and cloning. High fertilization efficiencies were...

Derivation and characterization of monkey embryonic stem cells

Embryonic stem (ES) cell based therapy carries great potential in the treatment of neurodegenerative diseases. However, before clinical application is realized, the safety, efficacy and feasibility of this therapeutic approach must be established in animal models. The rhesus macaque is physiologically and phylogenetically similar to the human, and therefore, is a clinically...

Sperm-induced oocyte activation in the rhesus monkey: nuclear and cytoplasmic changes following intracytoplasmic sperm injection.

Intracytoplasmic sperm injection (ICSI) has increased the potential of the assisted reproductive technologies to propagate mammalian species and has provided an opportunity for research into cell cycle control and the mechanisms involved in sperm-induced oocyte activation. We have investigated the efficacy of ICSI in the rhesus monkey, the mechanism of fertilization following...

Gene targeting in adult rhesus macaque fibroblasts

Background Gene targeting in nonhuman primates has the potential to produce critical animal models for translational studies related to human diseases. Successful gene targeting in fibroblasts followed by somatic cell nuclear transfer (SCNT) has been achieved in several species of large mammals but not yet in primates. Our goal was to establish the protocols necessary to achieve...

Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes

Wolf 1 0 Stem cell program, Genomics Research Centre , Academia Sinica, 128, Sec.2, Academia Road, Nankang Disl, 115 Taipei , Taiwan 1 Division of Reproductive Sciences, Oregon National Primate Research

A bispecific diabody directed against prostate-specific membrane antigen and CD3 induces T-cell mediated lysis of prostate cancer cells

, University of Freiburg , Schnzle Str. 1, 79104 Freiburg, Germany 2 P. Bhler P. Wolf D. Gierschner I. Schaber A. Katzenwadel W. Schultze-Seemann U. Wetterauer U. Elssser-Beile (&) Department of Urology ... diabodies could be a promising novel treatment option for prostate cancer. Methods A heterodimeric diabody speciWc for human PSMA and the T-cell antigen CD3 was constructed from P. Bhler and P. Wolf equally

Human gamete fusion can bypass beta1 integrin requirement.

Since alpha6beta1 integrin has been shown to function as a sperm adhesion receptor in the mouse, we investigated the potential role of beta1 integrin in the gamete fusion process in humans. The expression of beta1 integrin was morphologically analysed by indirect immunofluorescence and confocal microscopy. A homogeneous and intense staining was detected at the plasma membrane...

A bolus of recombinant human follicle stimulating hormone at midcycle induces periovulatory events following multiple follicular development in macaques.

The efficacy of follicle stimulating hormone (FSH) as an alternative to luteinizing hormone (LH)/human chorionic gonadotrophin (HCG) for the initiation of periovulatory events in primate follicles is unknown. A single bolus of 2500 IU recombinant (r)-hFSH was compared to 1000 IU r-HCG for its ability to promote oocyte nuclear maturation and fertilization, granulosa cell...

Odyssey: a solar system mission

. Anderson Global Aerospace, Los Angeles, USA 1 Ph. Bouyer Institut d'Optique Graduate School , Palaiseau, France 2 S. V. Progrebenko Joint Institute for VLBI in Europe , Dwingeloo, The Netherlands 3 P. Wolf

Advanced paternal age and de-novo complex chromosomal rearrangement in offspring.

We report one case of a de-novo complex chromosomal rearrangement (CCR), t(1;5;13)ins(14;13), in an abnormal 19-month-old boy. Clinical features associated were a mild facial dysmorphy and a psychomotor retardation. Parental ages were, respectively, 29 years for the mother and 60 years for the father. We point out the usefulness of fluorescence in-situ hybridization in...

No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients

Background: Outcomes of Ewing tumor (ET) patients treated with allogeneic stem cell transplantation (allo-SCT) were compared regarding the use of reduced-intensity conditioning (RIC) and high-intensity conditioning (HIC) regimens as well as human leukocyte antigen (HLA)-matched and HLA-mismatched grafts. Patients and methods: We retrospectively analyzed data of 87 ET patients...

Initiation of periovulatory events in gonadotrophin-stimulated macaques with varying doses of recombinant human chorionic gonadotrophin.

During in-vitro fertilization (IVF) cycles, a large bolus of human chorionic gonadotrophin (HCG) is used to induce periovulatory events, but the efficacy of lower doses is undefined. Following follicular stimulation in rhesus monkeys, oocyte nuclear maturation, IVF, granulosa cell luteinization and corpus luteum function were compared after injection of 100, 300 or 1000 IU...

Criminal Contempt and Trial by Jury

state legislatures. Robert P. Wolf situation is tantamount to determining if the maximum prescribed penalty exceeds six months. From this stage forward the proceedings would be identical. 75. See Green v