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A PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC Study): design and rationale of a family based randomized controlled trial in individuals with family history of premature coronary heart disease

Fogarty Fellowship, reviewed and copy edited this manuscript. Funding Panniyammakal Jeemon is currently supported by a clinical and public health intermediate fellowship from the Wellcome Trust-Department ... as well as all individual participants. Study team Panniyammakal Jeemon (PHFI), Harikrishnan S (SCTIMST), Sanjay G (SCTIMST), Sivasankaran Sivasubramonian (PHFI), Prabhakaran D (PHFI), Nikhil Tandon

Quality Improvement for Cardiovascular Disease Care in Low- and Middle-Income Countries: A Systematic Review

Background The majority of global cardiovascular disease (CVD) burden falls on people living in low- and middle-income countries (LMICs). In order to reduce preventable CVD mortality and morbidity, LMIC health systems and health care providers need to improve the delivery and quality of CVD care. Objectives As part of the Disease Control Priorities Three (DCP3) Study efforts...

Task shifting of frontline community health workers for cardiovascular risk reduction: design and rationale of a cluster randomised controlled trial (DISHA study) in India

supported by Indian Council of Medical Research, New Delhi, India. Panniyammakal Jeemon (PJ) was supported by a career development fellowship (2014 Feb-2014 June) from the Wellcome Trust, Public Health ... . DISHA study investigators and study team Centre for Chronic Disease Control, Delhi: Dr. Dorairaj Prabhakaran, PI; Dr. Sathya Prakash Manimunda, Co-PI; Dr. Panniyammakal Jeemon, Co-I; Dr. Dimple Kondal

Diagnostic accuracy of diffuse reflectance imaging for early detection of pre-malignant and malignant changes in the oral cavity: a feasibility study

Background Diffusely reflected light is influenced by cytologic and morphologic changes that take place during tissue transformation, such as, nuclear changes, extracellular matrix structure and composition as well as blood flow. Albeit with varying degree of sensitivity and specificity, the properties of diffusely reflected light in discriminating a variety of oral lesions have...

Tobacco use and nicotine dependency in a cross-sectional representative sample of 18,018 individuals in Andaman and Nicobar Islands, India

BackgroundData on prevalence, pattern of tobacco use, proportion of population dependent on nicotine and their determinants are important for developing and implementing tobacco control strategies. The aim of the study was to estimate the prevalence and determinants of tobacco use and nicotine dependency.MethodsA cross-sectional survey among a representative sample of 18,018...

Association of high sensitive C-reactive protein (hsCRP) with established cardiovascular risk factors in the Indian population

Introduction Inflammation, the key regulator of C-reactive protein (CRP) synthesis, plays a pivotal role in atherothrombotic cardiovascular disease. Methods High sensitivity CRP (hsCRP) analysis was carried out in randomly selected 600 individuals from the sentinel surveillance study in Indian industrial population (SSIP). The hsCRP was measured quantitatively by turbid metric...

Association between Gender, Process of Care Measures, and Outcomes in ACS in India: Results from the Detection and Management of Coronary Heart Disease (DEMAT) Registry

Background Studies from high-income countries have shown that women receive less aggressive diagnostics and treatment than men in acute coronary syndromes (ACS), though their short-term mortality does not appear to differ from men. Data on gender differences in ACS presentation, management, and outcomes are sparse in India. Methods and Results The Detection and Management of...