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8 papers found.
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Laparoscopic cholecystectomy for acute calculous cholecystitis: a retrospective study assessing risk factors for conversion and complications

Background The purpose of the study was to identify risk factors for conversion of laparoscopic cholecystectomy and risk factors for postoperative complications in acute calculous cholecystitis. The most common complications arising from cholecystectomy were also to be identified. Methods A total of 499 consecutive patients, who had undergone emergent cholecystectomy with...

Position paper: timely interventions in severe acute pancreatitis are crucial for survival

Severe acute pancreatitis has high mortality, but multiple and timely interventions can improve survival. Early in the course of the disease aggressive fluid resuscitation is needed for the prevention and treatment of shock. In conjunction with leaking capillaries this results in increased tissue edema, which may lead to intra-abdominal hypertension and abdominal compartment...

A new adult appendicitis score improves diagnostic accuracy of acute appendicitis - a prospective study

Background The aim of the study was to construct a new scoring system for more accurate diagnostics of acute appendicitis. Applying the new score into clinical practice could reduce the need of potentially harmful diagnostic imaging. Methods This prospective study enrolled 829 adults presenting with clinical suspicion of appendicitis, including 392 (47%) patients with...

Prophylactic open abdomen in patients with postoperative intra-abdominal hypertension

Panu Mentula 0 Ari Leppniemi 0 0 Department of Gastroenterological Surgery, Helsinki University Central Hospital , PL 340, 00029 HUS , Finland Postoperative intra-abdominal hypertension (IAH) is a

Laparoscopic versus open adhesiolysis for small bowel obstruction - a multicenter, prospective, randomized, controlled trial

Mikael Victorzon Paulina Salminen Vesa Koivukangas Eija Haukijrvi Berndt Enholm Ari Leppniemi 0 Panu Mentula 0 0 Department of Abdominal Surgery, Helsinki University Central Hospital , Haartmaninkatu 4

Circulating cytokines in predicting development of severe acute pancreatitis

Introduction Severe acute pancreatitis (AP) is associated with high morbidity and mortality. Early prediction of severe AP is needed to improve patient outcomes. The aim of the present study was to find novel cytokines or combinations of cytokines that can be used for the early identification of patients with AP at risk for severe disease. Methods We performed a prospective study...

Transverse laparostomy is feasible and effective in the treatment of abdominal compartment syndrome in severe acute pancreatitis

Background Only recently has the important role of abdominal compartment syndrome (ACS) been recognized as a contributing factor to the multiple organ failure commonly seen in severe acute pancreatitis (SAP). Decompressive laparostomy for ACS is a life-saving procedure usually performed through a midline incision followed by a negative pressure wound dressing. High risk of...

Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis

Introduction Disturbed protein C (PC) pathway homeostasis might contribute to the development of multiple organ failure (MOF) in acute pancreatitis (AP). We therefore evaluated circulating levels of PC and activated protein C (APC), evaluated monocyte deactivation in AP patients, and determined the relationship of these parameters to MOF. Patients and methods Thirty-one patients...