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118 papers found.
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Circulating 25-Hydroxyvitamin D3 in Relation to Renal Cell Carcinoma Incidence and Survival in the EPIC Cohort

Severi, Paolo Vineis); Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany (Tilman Kühn, Verena Katzke); Public Health Directorate, Asturias, Spain (Ramón Alonso de la Torre ... of Public Health, Imperial College London, London, United Kingdom (Paolo Vineis, H. Bas Bueno-de-Mesquita, Petra H. Peeters, Neil Murphy, Elio Riboli); Dopartimento di Medicina Clinica e Sperimentale

Quantifying the Dose-Response Relationship Between Circulating Folate Concentrations and Colorectal Cancer in Cohort Studies: A Meta-Analysis Based on a Flexible Meta-Regression Model

Most epidemiologic studies on folate intake suggest that folate may be protective against colorectal cancer, but the results on circulating (plasma or serum) folate are mostly inconclusive. We conducted a meta-analysis of case-control studies nested within prospective studies on circulating folate and colorectal cancer risk by using flexible meta-regression models to test the...

Biomarkers of Oxidative Stress and Risk of Developing Colorectal Cancer: A Cohort-nested Case-Control Study in the European Prospective Investigation Into Cancer and Nutrition

London, London, United Kingdom (Paolo Vineis); HuGeF Foundation, Turin, Italy (Paolo Vineis); Department of Clinical and Experimental Medicine, Faculty of Medicine, Federico II University, Naples, Italy

Association Between Total Number of Deaths, Diabetes Mellitus, Incident Cancers, and Haplotypes in Chromosomal Region 8q24 in a Prospective Study

, Silvia Polidoro, Alessandra Allione, Fabio Rosa, Floriana Voglino, Rossana Critelli, Alessia Russo, Paolo Vineis, Giuseppe Matullo); Department of Genetics, Biology, and Biochemistry, University of Torino ... Environment and Health, St. Marys Campus, Imperial College London, London, United Kingdom (Paolo Vineis). This work was supported by grants from the Associazione Italiana per le Ricerche sul Cancro, Italy (to

The Contribution of Risk Factors to the Higher Incidence of Invasive and In Situ Breast Cancers in Women With Higher Levels of Education in the European Prospective Investigation Into Cancer and Nutrition

. Reeves , Ve ronique Chajes, Sabina Rinaldi, Nadia Slimani, Valentina Gallo, Paolo Vineis, Elio Riboli, and H. Bas Bueno-de-Mesquita American Journal of Epidemiology The Author 2010. Published by Oxford ... Epidemiology and Public Health, Imperial College, London, United Kingdom (Petra H. Peeters, Valentina Gallo, Paolo Vineis, Elio Riboli); Department of Cardiology, Aarhus University Hospital, Aalborg, Denmark

Birth Order and Risk of Non-Hodgkin Lymphoma—True Association or Bias?

There is inconsistent evidence that increasing birth order may be associated with risk of non-Hodgkin lymphoma (NHL). The authors examined the association between birth order and related variables and NHL risk in a pooled analysis (1983–2005) of 13,535 cases and 16,427 controls from 18 case-control studies within the International Lymphoma Epidemiology Consortium (InterLymph...

Circulating C-Reactive Protein Concentrations and Risks of Colon and Rectal Cancer: A Nested Case-Control Study Within the European Prospective Investigation into Cancer and Nutrition

-Christine Boutron-Ruault, Francxoise Clavel-Chapelon, Sophie Morois, Domenico Palli, Vittorio Krogh, Rosario Tumino, Paolo Vineis, Salvatore Panico, Rudolf Kaaks, Sabine Rohrmann, Antonia Trichopoulou, Pagona ... Health and Primary Care, Imperial College London, London, United Kingdom (Elio Riboli, Paolo Vineis, Dora Romaguera, Teresa Norat); Department of Epidemiology, Institute of Public Health, Aarhus University

Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases

Seminara, Deborah M. Winn); Division of Epidemiology, Imperial College London, London, United Kingdom (Paolo Vineis); Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina

Serum Vitamin D and Risk of Prostate Cancer in a Case-Control Analysis Nested Within the European Prospective Investigation into Cancer and Nutrition (EPIC)

, Imperial College, London, United Kingdom (Paolo Vineis, Elio Riboli); Division of Epidemiology and Life Sciences, Institute for Scientific Interchange Foundation, Torino, Italy (Paolo Vineis); Molecular and

Smoking and Lymphoma Risk in the European Prospective Investigation into Cancer and Nutrition

Lymphomas are one of the few cancers that have been increasing in incidence over the past decades. So far, only a few established risk factors have been identified, including immunosuppression and viral infections. Recent evidence suggests etiologic heterogeneity of different lymphoma subtypes. Smoking may affect risk differently, depending on the lymphoma entity. The European...

Blood Pressure and Risk of Renal Cell Carcinoma in the European Prospective Investigation into Cancer and Nutrition

Elevated blood pressure has been implicated as a risk factor for renal cell carcinoma (RCC), but prospective studies were confined to men and did not consider the effect of antihypertensive medication. The authors examined the relation among blood pressure, antihypertensive medication, and RCC in the European Prospective Investigation into Cancer and Nutrition (EPIC). Blood...

Lactase Persistence and Bitter Taste Response: Instrumental Variables and Mendelian Randomization in Epidemiologic Studies of Dietary Factors and Cancer Risk

Consumption of dairy products seems to increase the risk of cancer at several sites, while intake of cruciferous vegetables could have protective effects. However, these dietary intakes are subject to measurement error, and associations with cancer could be due to confounders. Mendelian randomization has been suggested as a way to overcome confounding by exploiting the random...

Ethanol Intake and Risk of Lung Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Sabine Rohrmann ) Jakob Linseisen Hendriek C. Boshuizen John Whittaker Antonio Agudo Paolo Vineis Paolo Boffetta Majken K. Jensen Anja Olsen Kim Overvad Anne Tjnneland Marie-Christine Boutron-Ruault

XRCC3 and XPD/ERCC2 Single Nucleotide Polymorphisms and the Risk of Cancer: A HuGE Review

associations are weak and presently do not justify screening. This research was made possible by a grant from the Compagnia di San Paolo (Progetto Oncologia) to Dr. Paolo Vineis and a grant from the

A Network of Investigator Networks in Human Genome Epidemiology

Julia A. Newton Bishop 8 Thomas R. O'Brien Gloria Petersen 9 Elio Riboli () 6 Daniela Seminara 7 Emanuela Taioli 4 Andre G. Uitterlinden () 5 Paolo Vineis 2 Deborah M. Winn Georgia Salanti 1 Julian P. T

Pooled Analysis and Meta-analysis of Glutathione S-Transferase M1 and Bladder Cancer: A HuGE Review

Smoking is a known risk factor for bladder cancer. The product of the GSTM1 gene, glutathione S-transferase M1 (GSTM1), is involved in the detoxification of polycyclic aromatic hydrocarbons found in tobacco smoke; a homozygous deletion of this gene in approximately 50% of Caucasians and Asians results in a lack of GSTM1 enzyme activity. Most studies examining the relation between...

Significance testing in ridge regression for genetic data

, Kim Overvad, Francoise Clavel-Chapelon, Rudolf Kaaks, Heiner Boeing, Antonia Trichopoulou, Franco Berrino, Domenico Palli, Salvatore Panico, Rosario Tumino, Paolo Vineis, Bas Buneo de Mesquita, Petra

Human endogenous retroviruses and cancer prevention: evidence and prospects

Background Cancer is a significant and growing problem worldwide. While this increase may, in part, be attributed to increasing longevity, improved case notifications and risk-enhancing lifestyle (such as smoking, diet and obesity), hygiene-related factors resulting in immuno-regulatory failure may also play a major role and call for a revision of vaccination strategies to...

The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study

Background Diet has long been suspected to impact on breast cancer risk. In this study we evaluated whether the degree of adherence to a Mediterranean diet pattern modifies breast cancer risk amongst Greek-Cypriot women. Methods Subjects included 935 cases and 817 controls, all participating in the MASTOS case-control study in Cyprus. The study was approved by the Cyprus National...

Compliance with clinical practice guidelines for breast cancer treatment: a population-based study of quality-of-care indicators in Italy

Background It has been documented that variations exist in breast cancer treatment despite wide dissemination of clinical practice guidelines. The aim of this population-based study was to evaluate the impact of regional guidelines (Piedmont guidelines, PGL) for breast cancer diagnosis and treatment on quality-of-care indicators in the Northwestern Italian region of Piedmont...