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The Contribution of Individual Exercise Training Components to Clinical Outcomes in Randomised Controlled Trials of Cardiac Rehabilitation: A Systematic Review and Meta-regression

Meta-regression Bridget Abell 0 Paul Glasziou 0 Tammy Hoffmann 0 0 Centre for Research in Evidence-Based Practice, Faculty of Health Sciences and Medicine, Bond University , Gold Coast, Queensland 4229 ... Abell, Paul Glasziou and Tammy Hoffmann declare no financial relationships or conflicts of interest which may have influenced the results of this research. Publisher’s Note Springer Nature remains

Establishing a library of resources to help people understand key concepts in assessing treatment claims—The “Critical thinking and Appraisal Resource Library” (CARL)

Austvoll-Dahlgren, Paul Glasziou. Project administration: Iain Chalmers, Patricia Atkinson. Resources: John C. Castle, Iain Chalmers, Astrid Austvoll-Dahlgren, L. Kendall Krause, Lisa M. Schwartz, Steven ... , Amanda Burls, Tammy Hoffmann, Paul Glasziou. Validation: Douglas Badenoch, Astrid Austvoll-Dahlgren. Visualization: John C. Castle, Douglas Badenoch, Paul Glasziou. 9 / 12 Writing ± original draft: John

Communicating about overdiagnosis: Learning from community focus groups on osteoporosis

-investigator and internationally recognised expert in evidence based practice Professor Paul Glasziou, PG. RT was moderator for all focus groups, with technical assistance from RS. PG was also available in

Development of a Search Strategy for an Evidence Based Retrieval Service

Background Physicians are often encouraged to locate answers for their clinical queries via an evidence-based literature search approach. The methods used are often not clearly specified. Inappropriate search strategies, time constraint and contradictory information complicate evidence retrieval. Aims Our study aimed to develop a search strategy to answer clinical queries among ...

General Practitioners’ Decision Making about Primary Prevention of Cardiovascular Disease in Older Adults: A Qualitative Study

Background Primary cardiovascular disease (CVD) prevention in older people is challenging as they are a diverse group with varying needs, frequent presence of comorbidities, and are more susceptible to treatment harms. Moreover the potential benefits and harms of preventive medication for older people are uncertain. We explored GPs’ decision making about primary CVD prevention in ...

Development and validation of the guideline for reporting evidence-based practice educational interventions and teaching (GREET)

Maureen McEvoy, JG James Galipeau, PG Paul Glasziou, DM David Moher, MH Marilyn Hammick, LKL Lucy Lewis medical radiation, human movement, occupational therapy, population health, dietetics) and

The Role of Open Access in Reducing Waste in Medical Research

In a guest editorial, Paul Glasziou discusses waste in medical research and how this can be ameliorated through improving post-publication access. Please see later in the article for the Editors

A comparison of the performance of seven key bibliographic databases in identifying all relevant systematic reviews of interventions for hypertension

Background Bibliographic databases are the primary resource for identifying systematic reviews of health care interventions. Reliable retrieval of systematic reviews depends on the scope of indexing used by database providers. Therefore, searching one database may be insufficient, but it is unclear how many need to be searched. We sought to evaluate the performance of seven major ...

Factors influencing general practitioners’ decisions about cardiovascular disease risk reassessment: findings from experimental and interview studies

Background Guidelines on cardiovascular disease (CVD) risk reassessment intervals are unclear, potentially leading to detrimental practice variation: too frequent can result in overtreatment and greater strain on the healthcare system; too infrequent could result in the neglect of high risk patients who require medication. This study aimed to understand the different factors that ...

Faster title and abstract screening? Evaluating Abstrackr, a semi-automated online screening program for systematic reviewers

Glasziou 0 0 Centre for Research in Evidence-Based Practice, Bond University , Gold Coast , Australia Background: Citation screening is time consuming and inefficient. We sought to evaluate the performance

A Systematic Review of Studies Comparing Diagnostic Clinical Prediction Rules with Clinical Judgment

Background Diagnostic clinical prediction rules (CPRs) are developed to improve diagnosis or decrease diagnostic testing. Whether, and in what situations diagnostic CPRs improve upon clinical judgment is unclear. Methods and Findings We searched MEDLINE, Embase and CINAHL, with supplementary citation and reference checking for studies comparing CPRs and clinical judgment against a ...

Better duplicate detection for systematic reviewers: evaluation of Systematic Review Assistant-Deduplication Module

Background A major problem arising from searching across bibliographic databases is the retrieval of duplicate citations. Removing such duplicates is an essential task to ensure systematic reviewers do not waste time screening the same citation multiple times. Although reference management software use algorithms to remove duplicate records, this is only partially successful and ...

Rural Doctors’ Views on and Experiences with Evidence-Based Medicine: The FrEEDoM Qualitative Study

Background Evidence-based medicine is the integration of individual clinical expertise, best external evidence and patient values which was introduced more than two decades ago. Yet, primary care physicians in Malaysia face unique barriers in accessing scientific literature and applying it to their clinical practice. Aim This study aimed to explore the views and experiences of ...

Reporting of interventions in randomised trials: an audit of journal Instructions to Authors

Background A complete description of the intervention in a published trial report is necessary for readers to be able to use the intervention, yet the completeness of intervention descriptions in trials is very poor. Low awareness of the issue by authors, reviewers, and editors is part of the cause and providing specific instructions about intervention reporting to authors and ...

Systematic review of clinical practice guidelines recommendations about primary cardiovascular disease prevention for older adults

Background Clinical care for older adults is complex and represents a growing problem. They are a diverse patient group with varying needs, frequent presence of multiple comorbidities, and are more susceptible to treatment harms. Thus Clinical Practice Guidelines (CPGs) need to carefully consider older adults in order to guide clinicians. We reviewed CPG recommendations for primary ...

A randomised controlled trial of a blended learning education intervention for teaching evidence-based medicine

Background Few studies have been performed to inform how best to teach evidence-based medicine (EBM) to medical trainees. Current evidence can only conclude that any form of teaching increases EBM competency, but cannot distinguish which form of teaching is most effective at increasing student competency in EBM. This study compared the effectiveness of a blended learning (BL) ...

Problems with using mechanisms to solve the problem of extrapolation

synonym of reasoning [54]. Hence, we take pathophysiologic rationale to mean (roughly) the same as mechanistic reasoning. By way of support for the EBM view, Gordon Guyatt and Paul Glasziou (in

Systematic review automation technologies

Systematic reviews, a cornerstone of evidence-based medicine, are not produced quickly enough to support clinical practice. The cost of production, availability of the requisite expertise and timeliness are often quoted as major contributors for the delay. This detailed survey of the state of the art of information systems designed to support or automate individual tasks in the ...

Development and validation of the ACE tool: assessing medical trainees’ competency in evidence based medicine

Background While a variety of instruments have been developed to assess knowledge and skills in evidence based medicine (EBM), few assess all aspects of EBM - including knowledge, skills attitudes and behaviour - or have been psychometrically evaluated. The aim of this study was to develop and validate an instrument that evaluates medical trainees’ competency in EBM across ...

Communicating cardiovascular disease risk: an interview study of General Practitioners’ use of absolute risk within tailored communication strategies

Background Cardiovascular disease (CVD) prevention guidelines encourage assessment of absolute CVD risk - the probability of a CVD event within a fixed time period, based on the most predictive risk factors. However, few General Practitioners (GPs) use absolute CVD risk consistently, and communication difficulties have been identified as a barrier to changing practice. This study ...