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Dichotomous associations of liver pathology with hepatocellular carcinoma morphology in Middle Africa: the situation in Cameroon

ObjectiveThis study evaluates the occurrence of the various morphological subtypes of hepatocellular carcinoma (HCC) and their connections with some risk factors in Cameroonian patients. The database of the 360 liver biopsies received and associated medical records were reviewed for histological and demographic analysis. Archival formalin-fixed and paraffin embedded liver biopsy...

Droplet digital PCR detects high rate of TP53 R249S mutants in cell-free DNA of middle African patients with hepatocellular carcinoma

Paris Cedex 15 , France 9 Claudine Bekondi 10 Richard Njouom 11 Paul Jean Adrien Atangana 12 Dominique Noah Noah Hepatocellular carcinoma (HCC) is still a major killing malignancy in sub-Saharan Africa