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Increased hospitalizations for decompensated heart failure and acute myocardial infarction during mild winters: A seven-year experience in the public health system of the largest city in Latin America

for his support with statistics. Author Contributions Investigation: Renato Kawahisa Levin, Paulo H. N. Saldiva, Adriano Caixeta, Carolina Pereira, Salo V. Coslovsky, Antonio E. Pesaro. Methodology ... ± original draft: Renato Kawahisa Levin, Marcelo Katz, Paulo H. N. Saldiva, Adriano Caixeta, Antonio E. Pesaro. Writing ± review & editing: Renato Kawahisa Levin, Marcelo Katz, Paulo H. N. Saldiva, Adriano

Impact of Exhaled Breath Acetone in the Prognosis of Patients with Heart Failure with Reduced Ejection Fraction (HFrEF). One Year of Clinical Follow-up

Background The identification of new biomarkers of heart failure (HF) could help in its treatment. Previously, our group studied 89 patients with HF and showed that exhaled breath acetone (EBA) is a new noninvasive biomarker of HF diagnosis. However, there is no data about the relevance of EBA as a biomarker of prognosis. Objectives To evaluate whether EBA could give prognostic...

Lacrimal Cytokines Assessment in Subjects Exposed to Different Levels of Ambient Air Pollution in a Large Metropolitan Area

Background Air pollution is one of the most environmental health concerns in the world and has serious impact on human health, particularly in the mucous membranes of the respiratory tract and eyes. However, ocular hazardous effects to air pollutants are scarcely found in the literature. Design Panel study to evaluate the effect of different levels of ambient air pollution on...

Acute Cardiovascular and Inflammatory Toxicity Induced by Inhalation of Diesel and Biodiesel Exhaust Particles

Analysis of fuel emissions is crucial for understanding the pathogenesis of mortality because of air pollution. The objective of this study is to assess cardiovascular and inflammatory toxicity of diesel and biodiesel particles. Mice were exposed to fuels for 1 h. Heart rate (HR), heart rate variability, and blood pressure were obtained before exposure, as well as 30 and 60 min...

Composition of Inhaled Urban Air Particles Determines Acute Pulmonary Responses

Urban particles have a complex heterogeneous composition. To determine which components contribute to the toxicity of inhaled ambient air particles, six different experiments were done using normal Sprague-Dawley rats exposed for 3 consecutive days, for 5 h per day, to either concentrated air particles (CAPs) or filtered air sham conditions (8–12 animals per experimental group...

Electrocardiographic Changes during Exposure to Residual Oil Fly Ash (ROFA) Particles in a Rat Model of Myocardial Infarction

Epidemiological studies have reported a positive association of short-term increases in ambient particulate matter (PM) with daily mortality and hospital admissions for cardiovascular disease. Although patients with cardiopulmonary disease appear to be most at risk, particulate-related cardiac effects following myocardial infarction (MI) have not been examined. To improve...