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The effects of an unsupervised water exercise program on low back pain and sick leave among healthy pregnant women – A randomised controlled trial

introduction of the Hegaard. Hegaard. Conceptualization: Ann Tabor, Hanne Albert, Susanne Rosthøj, Peter Damm, Hanne K. Data curation: Mette G. Backhausen, Susanne Rosthøj, Hanne K. Hegaard. Formal analysis ... : Susanne Rosthøj. Funding acquisition: Mette G. Backhausen, Hanne K. Hegaard. Investigation: Mette G. Backhausen, Ann Tabor, Susanne Rosthøj, Peter Damm, Hanne K. Methodology: Hanne Albert, Peter Damm

Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy

Background Offspring of women with diabetes in pregnancy are at increased risk of type 2 diabetes mellitus (T2DM), potentially mediated by epigenetic mechanisms. The adipokines leptin, adiponectin, and resistin (genes: LEP, ADIPOQ, RETN) play key roles in the pathophysiology of T2DM. We hypothesized that offspring exposed to maternal diabetes exhibit alterations in epigenetic ...

Assessment of Attention Deficits in Adolescent Offspring Exposed to Maternal Type 1 Diabetes

Objective The aim of this study was to examine the potential association between intrauterine exposure to maternal diabetes and attention deficits in the offspring. Research design and methods Adolescent offspring of a prospectively followed cohort of women with type 1 diabetes (n = 269) and a control group from the background population (n = 293) participated in a follow-up ...

Alcohol consumption and binge drinking in early pregnancy. A cross-sectional study with data from the Copenhagen Pregnancy Cohort

Background Since 2007 the Danish Health and Medicines Authority has advised total alcohol abstinence from the time of trying to conceive and throughout pregnancy. The prevalence of binge drinking among pregnant Danish women has nevertheless been reported to be up to 48 % during early pregnancy. Since the introduction of the recommendation of total abstinence, no studies have ...

Risk Factors for Hyperglycaemia in Pregnancy in Tamil Nadu, India

Introduction Hyperglycaemia in pregnancy (HIP), i.e. gestational diabetes mellitus (GDM) and diabetes in pregnancy (DIP), increases the risk of various short- and long-term adverse outcomes. However, much remains to be understood about the role of different risk factors in development of HIP. Objective The aims of this observational study were to examine the role of potential risk ...

Compliance with national recommendations for exercise during early pregnancy in a Danish cohort

Background Exercise during pregnancy is associated with health benefits for both the mother and the fetus, and is therefore recommended in several national guidelines. Only few studies investigate whether these guideline recommendations are met. The aims of this study were 1. To assess the prevalence of pregnant women meeting the Danish recommendations for exercise during early ...

Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria

Background Placental malaria occurs when Plasmodium falciparum infected erythrocytes sequester in the placenta. Placental parasite isolates bind to chondroitin sulphate A (CSA) by expression of VAR2CSA on the surface of infected erythrocytes, but may sequester by other VAR2CSA mediated mechanisms, such as binding to immunoglobulins. Furthermore, other parasite antigens have been ...

Poor pregnancy outcome after octreotide treatment during pregnancy for familial hyperinsulinemic hypoglycemia: a case report

Background Late familial hyperinsulinemic hypoglycemia is characterized by recurrent episodes of hypoglycemia and an inappropriate insulinemic response. Treatment with octreotide (somatostatin analogue) reduces the prevalence of clinical significant hypoglycemia and might be beneficial during pregnancy. To our knowledge this is the first report of a woman with late familial ...

Higher Gestational Weight Gain Is Associated With Increasing Offspring Birth Weight Independent of Maternal Glycemic Control in Women With Type 1 Diabetes

OBJECTIVE We evaluate the association between gestational weight gain and offspring birth weight in singleton term pregnancies of women with type 1 diabetes.

From screening to postpartum follow-up – the determinants and barriers for gestational diabetes mellitus (GDM) services, a systematic review

Background Gestational diabetes mellitus (GDM) – a transitory form of diabetes first recognised during pregnancy complicates between < 1% and 28% of all pregnancies. GDM has important short and long-term health consequences for both the mother and her offspring. To prevent adverse pregnancy outcomes and to prevent or delay future onset of type 2 diabetes in mother and offspring, ...

Maternal and fetal recovery after severe respiratory failure due to influenza: a case report

Peter Damm 0 0 Department of Obstetrics, Center for Pregnant Women with Diabetes, The Juliane Marie Centre, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen , Copenhagen , Denmark 1

Increased metabolic risk in adolescent offspring of mothers with type 1 diabetes: the EPICOM study

Aims/hypothesis We aimed to investigate metabolic risk factors, insulin sensitivity and insulin secretion in adolescent offspring of mothers with type 1 diabetes compared with offspring of non-diabetic mothers. Methods During 1993–1999, pregnancies of women with type 1 diabetes in Denmark were prospectively reported to a central registry in the Danish Diabetes Association. Data ...

The Effect of Real-Time Continuous Glucose Monitoring in Pregnant Women With Diabetes: A randomized controlled trial

ANNA L. SECHER LENE RINGHOLM PHD HENRIK U. ANDERSEN DMSC PETER DAMM DMSC ELISABETH R. MATHIESEN DMSC OBJECTIVEdTo assess whether intermittent real-time continuous glucose monitoring (CGM) improves

Women Born Preterm or with Inappropriate Weight for Gestational Age Are at Risk of Subsequent Gestational Diabetes and Pre-Eclampsia

Introduction Low birthweight, which can be caused by inappropriate intrauterine growth or prematurity, is associated with development of gestational diabetes mellitus (GDM) as well as pre-eclampsia later in life, but the relative effects of prematurity and inappropriate intrauterine growth remain uncertain. Methods Through nation-wide registries we identified all Danish mothers in ...

Impact of Restricted Maternal Weight Gain on Fetal Growth and Perinatal Morbidity in Obese Women With Type 2 Diabetes

OBJECTIVE Since January 2008, obese women with type 2 diabetes were advised to gain 0–5 kg during pregnancy. The aim with this study was to evaluate fetal growth and perinatal morbidity in relation to gestational weight gain in these women.

Results From a European Multicenter Randomized Trial of Physical Activity and/or Healthy Eating to Reduce the Risk of Gestational Diabetes Mellitus: The DALI Lifestyle Pilot

Rosa Corcoy Juan M. Adelantado Fidelma Dunne Gernot Desoye Ju¨rgen Harreiter Alexandra Kautzky-Willer Peter Damm Elisabeth R. Mathiesen Dorte M. Jensen Lise Lotte Andersen Annunziata Lapolla Maria Dalfra

Physical activity, depressed mood and pregnancy worries in European obese pregnant women: results from the DALI study

David Hill 14 Peter Damm 11 Elisabeth R. Mathiesen 11 Ewa Wender-Ozegowska 12 Agnieszka Zawiejska 12 Pablo Rebollo 9 Annunziata Lapolla 10 Maria G. Dalfrà 10 Stefano Del Prato 7 Alessandra Bertolotto 7