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37 papers found.
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Evaluation of Hirst-type spore traps in outdoor Aspergillaceae monitoring during large demolition work in hospital

Conceptualization: Sophie Tiphaine Loeffert, Philippe Vanhems, Thomas BeÂnet, Marie-Paule Gustin. Formal analysis: Estelle Tissot, Marie-Paule Gustin. Investigation: Sophie Tiphaine Loeffert. Methodology: Sophie ... Gustin. Supervision: Philippe Vanhems, Marie-Paule Gustin. Validation: Philippe Vanhems, Marie-Paule Gustin. Writing ± original draft: Sophie Tiphaine Loeffert. Writing ± review & editing: Philippe

Evaluation of hirst-type spore trap to monitor environmental fungal load in hospital

The main purpose was to validate the use of outdoor-indoor volumetric impaction sampler with Hirst-type spore traps (HTSTs) to continuously monitor fungal load in order to prevent invasive fungal infections during major structural work in hospital settings. For 4 weeks, outdoor fungal loads were quantified continuously by 3 HTSTs. Indoor air was sampled by both HTST and viable...

Predictors of haemodynamic instability during the changeover of norepinephrine infusion pumps

Background Changeovers of norepinephrine infusion pumps (CNIPs) frequently lead to haemodynamic instability. The aim of this study was to identify risk factors for haemodynamic instability associated with CNIP, independent of the method used to perform the relay. Methods We performed a prospective study, in a university-affiliated intensive care unit. Over a 1-year period, all...

Targeted screening for third-generation cephalosporin-resistant Enterobacteriaceae carriage among patients admitted to intensive care units: a quasi-experimental study

Introduction Identification of third-generation, cephalosporin-resistant Enterobacteriaceae (3GC-RE) carriers by rectal screening at admission seems to be an important step in the prevention of transmission and outbreaks; however, little is known about its effectiveness. The aim of this study was to evaluate the impact of ‘targeted screening’ at patient admission to intensive...

Etiology and Factors Associated with Pneumonia in Children under 5 Years of Age in Mali: A Prospective Case-Control Study

Background There are very limited data on children with pneumonia in Mali. The objective was to assess the etiology and factors associated with community-acquired pneumonia in hospitalized children <5 years of age in Mali. Methods A prospective hospital-based case-control study was implemented in the Pediatric department of Gabriel Touré University Hospital at Bamako, Mali...

The effect of adherence to guidelines for initial antiretroviral therapy on 1-year outcomes: a French cohort study

ViiV and MSD and has received travel expenses from Abbott, Boehringer, BMS, Gilead, Janssen, MSD, Roche and ViiV. Philippe Vanhems has received research grants from Sanofi Pasteur. Thomas Bnet, Corinne

Detection of Temporal Clusters of Healthcare-Associated Infections or Colonizations with Pseudomonas aeruginosa in Two Hospitals: Comparison of SaTScan and WHONET Software Packages

The identification of temporal clusters of healthcare-associated colonizations or infections is a challenge in infection control. WHONET software is available to achieve these objectives using laboratory databases of hospitals but it has never been compared with SaTScan regarding its detection performance. This study provided the opportunity to evaluate the performance of WHONET...

Trypanosoma-Cruzi Cross-Reactive Antibodies Longitudinal Follow-Up: A Prospective Observational Study in Hematopoietic Stem Cell Transplantation

Antibodies named TcCRA “Trypanosoma cruzi Cross Reactive Antibodies” were detected in 47% of blood donors from French population unexposed to the parasite. In order to evaluate the passive or active transmissibility of TcCRA and further characterize its role and etiology, we have conducted a study in a cohort of 47 patients who underwent allogeneic Hematopoietic Stem Cell...

Five years of hospital based surveillance of influenza-like illness and influenza in a short-stay geriatric unit

Background Data on influenza in the healthcare setting are often based on retrospective investigations of outbreaks and a few studies described influenza during several consecutive seasons. The aim of the present work is to report data on influenza like illness (ILI) and influenza from 5-year prospective surveillance in a short-stay geriatrics unit. Findings A short stay...

A statistical model to assess the risk of communicable diseases associated with multiple exposures in healthcare settings

Background The occurrence of communicable diseases (CD) depends on exposure to contagious persons. The effects of exposure to CD are delayed in time and contagious persons remain contagious for several days during which their contagiousness varies. Moreover when multiple exposures occur, it is difficult to know which exposure is associated with the CD. Methods A statistical model...

Abdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome

Philippe Vanhems 5 Casiano Barrera Groba 4 Marc Leone 3 Jean-Louis Vincent 7 for the EPIC II Investigators 0 Department of Critical Care Medicine, Ghent University Hospital , De Pintelaan 185, 9000 Gent

Impact of surveillance of hospital-acquired infections on the incidence of ventilator-associated pneumonia in intensive care units: a quasi-experimental study

Introduction The preventive impact of hospital-acquired infection (HAI) surveillance is difficult to assess. Our objective was to investigate the effect of HAI surveillance disruption on ventilator-associated pneumonia (VAP) incidence. Methods A quasi-experimental study with an intervention group and a control group was conducted between 1 January 2004 and 31 December 2010 in two...

Disparities of Perceptions and Practices Related to Cervical Cancer Prevention and the Acceptability of HPV Vaccination According to Educational Level in a French Cross-Sectional Survey of 18–65 Years Old Women

Introduction We aimed to study the relationships between educational level, women's knowledge about cervical cancer (CC), and acceptance of HPV vaccination for their daughters. Methods We analysed data from a quantitative (self-administrated questionnaire) and qualitative (semi-structured interviews) cross-sectional study performed in 2008 among 1,229 French 18–65-year-old women...

Infections, antibiotic treatment and mortality in patients admitted to ICUs in countries considered to have high levels of antibiotic resistance compared to those with low levels

Hkan Hanberger 4 Massimo Antonelli 2 Martin Holmbom 4 Jeffrey Lipman 1 Peter Pickkers 8 Marc Leone 7 Jordi Rello 6 Yasser Sakr 5 Sten M Walther 10 Philippe Vanhems 9 Jean-Louis Vincent 0 3 for the

Incidence of Hospital-Acquired Pneumonia, Bacteraemia and Urinary Tract Infections in Patients with Haematological Malignancies, 2004–2010: A Surveillance-Based Study

Objective This study charted incidence trends of hospital-acquired (HA) pneumonia, bacteraemia and urinary tract infections (UTI) in a haematology department. Methods Prospective surveillance of hospital-acquired infections (HAI) was undertaken in a 42-bed haematology department of a university hospital. All patients hospitalized ≥48 hours between 1st January 2004 and 31st...

Diversity of Trends of Viremia and T-Cell Markers in Experimental Acute Feline Immunodeficiency Virus Infection

Objective The early events of human immunodeficiency virus infection seem critical for progression toward disease and antiretroviral therapy initiation. We wanted to clarify some still unknown prognostic relationships between inoculum size and changes in various immunological and virological markers. Feline immunodeficiency virus infection could be a helpful model. Methods...

Estimating Potential Infection Transmission Routes in Hospital Wards Using Wearable Proximity Sensors

Background Contacts between patients, patients and health care workers (HCWs) and among HCWs represent one of the important routes of transmission of hospital-acquired infections (HAI). A detailed description and quantification of contacts in hospitals provides key information for HAIs epidemiology and for the design and validation of control measures. Methods and Findings We...

Evaluation of adult dTPaP vaccination coverage in France: experience in Lyon city, 2010–2011

Background Compliance with official recommendations can be assessed by evaluating vaccination coverage (VC) in populations. The main objective of our study was to assess VC of adults against diphtheria, tetanus, poliomyelitis and pertussis (dTPaP) according to age. The second objective was to explore if vaccination status could be confirmed by documentation. Methods A cross...

Perception of epidemic's related anxiety in the General French Population: a cross-sectional study in the Rhône-Alpes region

Background To efficiently plan appropriate public health interventions during possible epidemics, governments must take into consideration the following factors about the general population: their knowledge of epidemics, their fears of and psychological responses to them, their level of compliance with government measures and their communities' trusted sources of information...

Anti-Trypanosoma cruzi Cross-Reactive Antibodies Detected at High Rate in Non-Exposed Individuals Living in Non-Endemic Regions: Seroprevalence and Association to Other Viral Serologies

Cross-reactive antibodies are characterized by their recognition of antigens that are different from the trigger immunogen. This happens when the similarity between two different antigenic determinants becomes adequate enough to enable a specific binding with such cross-reactive antibodies. In the present manuscript, we report the presence, at an “abnormal” high frequency, of...