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Causality in cancer research: a journey through models in molecular epidemiology and their philosophical interpretation

-210176796] to Paolo Vineis, and partially supported by the Arts and Humanities Research Council via grant AH/M005917/1 to Phyllis Illari and Federica Russo. The authors thank Christopher Wild for comments on

Introduction: Evidence and Causality in the Sciences

medical trials. In Mechanisms and the evidence hierarchy, Brendan Clarke, Donald Gillies, Phyllis Illari, Federica Russo, and Jon Williamson instead focus on the bottom layers of the hierarchies