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A de novo complex chromosome rearrangement associated with multisystematic abnormalities, a case report

Complex chromosomal rearrangements (CCRs) are constitutional structural rearrangements that involve three or more chromosomes or that have more than two breakpoints. Here, we describe a four-way CCR involving chromosomes 4, 5, 6 and 8. The patient had mild multisystematic abnormalities during his development, including defects in his eyes and teeth, exomphalos and ...

Oral administration of Chinese herbal medicine during gestation period for preventing hemolytic disease of the newborn due to ABO incompatibility: A systematic review of randomized controlled trials

-JSMS037) from the Beijing University of Chinese Medicine. Jian-Ping Liu is supported by the Research Capacity Establishment Grant (No. Background Methods To systematically assess the safety and ... Establishment Grant (No. 2015JYB-JSMS037) from the Beijing University of Chinese Medicine. Jian-Ping Liu is supported by the Research Capacity Establishment Grant (No. 201207012) from the State Administration of

A promising tool for surgical lipotransfer: a constant pressure and quantity injection device in facial fat grafting

Background The purpose of this study was to preliminarily assess a constant pressure and quantity fat granule injection device for minimal invasive properties in clinic. Methods A retrospective controlled study was carried out, from October 2013 to January 2015, on 76 female healthy patients aged between 26 and 53 years at the General Hospital of Lanzhou Military Command, China. To ...

Transcriptomic variation of eyestalk reveals the genes and biological processes associated with molting in Portunus trituberculatus

Background Molting is an essential biological process throughout the life history of crustaceans, which is regulated by many neuropeptide hormones expressed in the eyestalk. To better understand the molting mechanism in Portunus trituberculatus, we used digital gene expression (DGE) to analyze single eyestalk samples during the molting cycle by high-throughput sequencing. Results ...

A novel constructed SPT15 mutagenesis library of Saccharomyces cerevisiae by using gTME technique for enhanced ethanol production

Youran Li 0 Shuang Ping Liu 0 Gui Yang Shi 0 0 The Key Laboratory of Industrial Biotechnology, Ministry of Education, National Engineering Laboratory for Cereal Fermentation Technology, School of

‘Waiting impulsivity’ in isolation-reared and socially-reared rats: effects of amphetamine

research was supported by a Wellcome Trust Programme grant to TWR and by BBSRC funding to LSW and by a PhD scholarship from the government of Taiwan to Dr. Yia-Ping Liu. We thank Dr. Emily Jordan for her

Prevalence of Lower Urinary Tract Symptoms in China, Taiwan, and South Korea: Results from a Cross-Sectional, Population-Based Study

. Limin Liao has acted as a consultant for Astellas during a meeting to discuss the publications from the study. Shih-Ping Liu has acted as a consultant for Astellas during a meeting to discuss the

Andrographis paniculata (Chuān Xīn Lián) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis

Introduction Antimicrobial resistance (AMR) is a substantial threat to public health. Safe and effective alternatives are required to reduce unnecessary antibiotic prescribing. Andrographis Paniculata (A. Paniculata, Chuān Xīn Lián) has traditionally been used in Indian and Chinese herbal medicine for cough, cold and influenza, suggesting a role in respiratory tract infections ...

Testosterone suppresses uropathogenic Escherichia coli invasion and colonization within prostate cells and inhibits inflammatory responses through JAK/STAT-1 signaling pathway

Prostatitis is a common condition in adult men of all ages. Uropathogenic Escherichia coli (UPEC) are most frequent pathogen involved in bacterial prostatitis by refluxing the infected urine into prostatic ducts and resulting in an ascending urethral infection. However, the study about the mechanisms of UPEC to invade, replicate and persist in normal prostate epithelial cell is ...

Rheumatoid arthritis is associated with rs17337023 polymorphism and increased serum level of the EGFR protein

acquisition: Shih-Yin Chen, Fuu-Jen Tsai. Investigation: Chung-Ming Huang, Yu-Chuen Huang, Yuan-Yen Chang, Shih-Yin Chen. Methodology: Hsin-Han Chen, Da-Chung Chen, Shih-Ping Liu, Shih-Yin Chen. Project

Metabolomic mechanisms of gypenoside against liver fibrosis in rats: An integrative analysis of proteomics and metabolomics data

Aims To investigate mechanisms and altered pathways of gypenoside against carbon tetrachloride (CCl4)-induced liver fibrosis based on integrative analysis of proteomics and metabolomics data. Methods CCl4-induced liver fibrosis rats were administrated gypenoside. The anti-fibrosis effects were evaluated by histomorphology and liver hydroxyproline (Hyp) content. Protein profiling ...

Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan

Three new pyridine type alkaloids, (−)-vinmajpyridines A–C (1–3), along with two known alkaloids, have been isolated from the aerial parts of Vinca major cultivated in Pakistan. Their structures have been elucidated by means of NMR and HRESIMS spectroscopic data. The new alkaloids were evaluated for their cytotoxicity against glioma initiating cell lines (GITC-3# and GITC-18#), ...

Formation and distribution characteristics of Proterozoic–Lower Paleozoic marine giant oil and gas fields worldwide

There are rich oil and gas resources in marine carbonate strata worldwide. Although most of the oil and gas reserves discovered so far are mainly distributed in Mesozoic, Cenozoic, and upper Paleozoic strata, oil and gas exploration in the Proterozoic–Lower Paleozoic (PLP) strata—the oldest marine strata—has been very limited. To more clearly understand the oil and gas formation ...

Structure alignment-based classification of RNA-binding pockets reveals regional RNA recognition motifs on protein surfaces

Background Many critical biological processes are strongly related to protein-RNA interactions. Revealing the protein structure motifs for RNA-binding will provide valuable information for deciphering protein-RNA recognition mechanisms and benefit complementary structural design in bioengineering. RNA-binding events often take place at pockets on protein surfaces. The structural ...

Wogonin as a targeted therapeutic agent for EBV (+) lymphoma cells involved in LMP1/NF-κB/miR-155/PU.1 pathway

Background Wogonin is an encouraging choice for clinical use owing to its potent anti-tumor and anti-inflammatory effects with the high safety profile. However, wogonin for targeted therapy of lymphoma was not well addressed. In this study, we focused on its anticancer effect alongside with the underlying mechanisms for targeted therapy in EBV-positive lymphoma. This will ...

Estimation of prevalence of sarcopenia by using a new bioelectrical impedance analysis in Chinese community-dwelling elderly people

Background The aim of the present study was to validate the usefulness of the new octapolar multifrequency bioelectrical impedance analysis (BIA) for assessment of appendicular skeletal muscle mass (ASM) by comparing it with that of dual-energy X-ray absorptiometry (DXA) and to investigate the prevalence of sarcopenia in Chinese community-dwelling elderly according to Asian Working ...

The analysis of the SIRS alcoholism models with relapse on weighted networks

Two SIRS alcoholism models with relapse on networks with fixed and adaptive weight are introduced. The spread of alcoholism threshold \({R_0}\) is calculated by the next generation matrix method. For the model with fixed weight, we prove that when \({R_0} 1\), the alcoholism equilibrium is global attractivity, then the density of alcoholics will remain in a stable value. For the ...

Polygalacturonase gene pgxB in Aspergillus niger is a virulence factor in apple fruit

Aspergillus niger, a saprophytic fungus, is widely distributed in soil, air and cereals, and can cause postharvest diseases in fruit. Polygalacturonase (PG) is one of the main enzymes in fungal pathogens to degrade plant cell wall. To evaluate whether the deletion of an exo-polygalacturonase gene pgxB would influence fungal pathogenicity to fruit, pgxB gene was deleted in ...

Health-related quality of life as measured with the Short-Form 36 (SF-36) questionnaire in patients with recurrent vulvovaginal candidiasis

Background Recurrent vulvovaginal candidiasis (RVVC) has a poor therapeutic outcome and a severe impact on women and their partners, both physically and psychologically. Health-related quality of life (HRQOL) is significantly affected in patients with RVVC; however, little is known about HRQOL in patients with this disease. In this study, we aim to identify the clinical and ...