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Study on three independent parameters of focal mechanism solution

In this paper, the relationships of the plunges and azimuths of T and P axes versus the strikes, dips, and rakes of two seismic nodal planes were derived to provide reference for earthquake researchers. The independence of the plunges and azimuths of T, B, and P axes in focal mechanism solution was discussed, and it was concluded that three parameters, i.e., the azimuths of T, B ...

A farm-level precision land management framework based on integer programming

Farmland management involves several planning and decision making tasks including seed selection and irrigation management. A farm-level precision farmland management model based on mixed integer linear programming is proposed in this study. Optimal decisions are designed for pre-season planning of crops and irrigation water allocation. The model captures the effect of size and ...

Performances of Different Fragment Sizes for Reduced Representation Bisulfite Sequencing in Pigs

Background Reduced representation bisulfite sequencing (RRBS) has been widely used to profile genome-scale DNA methylation in mammalian genomes. However, the applications and technical performances of RRBS with different fragment sizes have not been systematically reported in pigs, which serve as one of the important biomedical models for humans. The aims of this study were to ...

miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4

Background Dysregulation of microRNAs (miRNAs) is actively involved in the pathogenesis and tumorigenicity of colorectal cancer (CRC). miR-296 was found to play either oncogenic or tumor suppressive role in human cancers. However, the status of miR-296 and its function in CRC remain unknown. Methods The expression of miR-296 was confirmed by qRT-PCR in CRC tissues and cells, and ...

A Review of the Novel Application and Potential Adverse Effects of Proton Pump Inhibitors

, Yue-Qi Li, Lei Yu, Zi-Qing-Yun Yuan, Ling Meng, Hong-Wen Zhang and Yong-Qing Wang declare no conflict of interest. Compliance with Ethics Guidelines. This article is based on previously conducted

Saxifragifolin D attenuates phagosome maturation arrest in Mycobacterium tuberculosis-infected macrophages via an AMPK and VPS34-dependent pathway

Saxifragifolin D (SD), a traditional Chinese medicine, is a pentacyclic triterpenoid compound first isolated from Androsace umbellata. Various plant triterpenoids have been reported to exhibit antitubercular activity. In this study, THP-1-derived macrophages were infected with an attenuated M. tuberculosis (M.tb) strain, H37Ra. Intracellular replication of M.tb was evaluated by ...

Erratum to: Biomechanical consideration of prosthesis selection in hybrid surgery for bi-level cervical disc degenerative diseases

Department of Orthopaedics, The 306th Hospital of People's Liberation Army , Beijing , People's Republic of China a mistake and has been corrected. First and last names of the author Qi Li were interchanged

Rational Design of Disulfide Bonds Increases Thermostability of a Mesophilic 1,3-1,4-β-Glucanase from Bacillus terquilensis

1,3–1,4-β-glucanase is an important biocatalyst in brewing industry and animal feed industry, while its low thermostability often reduces its application performance. In this study, the thermostability of a mesophilic β-glucanase from Bacillus terquilensis was enhanced by rational design and engineering of disulfide bonds in the protein structure. Protein spatial configuration was ...

Genetic Variation and Breeding Signature in Mass Selection Lines of the Pacific Oyster (Crassostrea gigas) Assessed by SNP Markers

populations. (b) Graph of delta K. (TIF) S1 Table. Summary of the statistics for 103 SNP loci in the wild and selected Crassostrea gigas populations. (XLS) Acknowledgments We wish to thank Qi Li for his help

Design of fiber magnetic field sensor based on fiber Bragg grating Fabry-Perot cavity ring-down spectroscopy

Design of Fiber Magnetic Field Sensor Based on Fiber Bragg Grating Fabry-Perot Cavity Ring-Down Spectroscopy Qi LI 0 Haiyan CHEN 0 Corresponding author: Haiyan CHEN 0 0 School of Physics and ... r = 0.98, the refractive index of the single mode fiber is 1.5, and the cavity length is 0.5 m. The effect of the external magnetic field on Qi LI et al.: Design of Fiber Magnetic Field Sensor Based

Lipopolysaccharide induces SBD-1 expression via the P38 MAPK signaling pathway in ovine oviduct epithelial cells

Background Beta defensins are secreted from ovine oviduct epithelial cells (OOECs) in response to microbial infection, and are potential alternatives to antibiotic agents in the treatment of microorganism infection, particularly given the abuse of antibiotic agents and the increasing number of drug-resistant bacteria. The aberrant expression of defensins may result in disorders ...

Helicobacter pylori promotes angiogenesis depending on Wnt/beta-catenin-mediated vascular endothelial growth factor via the cyclooxygenase-2 pathway in gastric cancer

Liu 0 Ning Zhou 0 Ni Chai Xuan Liu Haili Jiang Qiong Wu Qi Li 0 Equal contributors Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine , No. 528

Comparative Transcriptome Analysis of the Pacific Oyster Crassostrea gigas Characterized by Shell Colors: Identification of Genetic Bases Potentially Involved in Pigmentation

Background Shell color polymorphisms of Mollusca have contributed to development of evolutionary biology and population genetics, while the genetic bases and molecular mechanisms underlying shell pigmentation are poorly understood. The Pacific oyster (Crassostrea gigas) is one of the most important farmed oysters worldwide. Through successive family selection, four shell color ...

CPA-7 influences immune profile and elicits anti-prostate cancer effects by inhibiting activated STAT3

Background Platinum-based chemotherapy is emerging as the first line of treatment for castration resistant prostate cancer. Among the family of platinum (IV)-based compounds, a member known as CPA-7 inhibits the growth of multiple cancer cell lines. However, how and to what extent CPA-7 elicits its anti-prostate cancer effects in vivo is largely unknown. Methods In this study, we ...

Fish oil alleviated high-fat diet–induced non-alcoholic fatty liver disease via regulating hepatic lipids metabolism and metaflammation: a transcriptomic study

experiment. Hualin Wang, Qi Li, Lei He and Na Li performed the RNA-seq transcriptomic analysis analysis. Hualin Wang, Zhiguo Liu and Fahu Yuan wrote the manuscript. All authors read and approved the final

Disease Burden Due to Herpes Zoster among Population Aged ≥50 Years Old in China: A Community Based Retrospective Survey

Objective To understand the disease burden due to Herpes Zoster (HZ) among people aged ≥50 years old in China and provide baseline data for future similar studies, and provide evidence for development of herpes zoster vaccination strategy. Methods Retrospective cohort study was conducted in 4 townships and one community. A questionnaire was used to collect information on incidence ...

Use of a Green Familiar Faces Paradigm Improves P300-Speller Brain-Computer Interface Performance

Background A recent study showed improved performance of the P300-speller when the flashing row or column was overlaid with translucent pictures of familiar faces (FF spelling paradigm). However, the performance of the P300-speller is not yet satisfactory due to its low classification accuracy and information transfer rate. Objective To investigate whether P300-speller performance ...

Screening Reliable Reference Genes for RT-qPCR Analysis of Gene Expression in Moringa oleifera

Moringa oleifera is a promising plant species for oil and forage, but its genetic improvement is limited. Our current breeding program in this species focuses on exploiting the functional genes associated with important agronomical traits. Here, we screened reliable reference genes for accurately quantifying the expression of target genes using the technique of real-time ...

Optimization of an organic photovoltaic device via modulation of thickness of photoactive and optical spacer layers

We examine the modulation effects of thicknesses of both a photoactive layer (a bulk-heterojunction (BHJ) of poly(3-hexylthiophene) and [6,6]-phenyl-C61-butyric acid methyl ester (P3HT:PCBM)) and an optical spacer of a transparent metal oxide, for power conversion efficiency optimization of organic photovoltaic devices. The redistribution of the optical intensity at the photoactive ...