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Voluntary disclosure of internal control and auditor’s attestation: evidence from China

We examine what determines a firm’s decision to disclose a self-assessment report on its internal control (IC) system and to further attain an auditor’s attestation on the report, using a sample of firms from the Shanghai Stock Exchange during the period 2006–2010. We hypothesize and find supporting evidence that the likelihood of having voluntary disclosure of IC self-assessment...

Extracranial metastases of high-grade glioma: the clinical characteristics and mechanism

This presentation of two cases and literature review discusses the epidemiology, clinical manifestations, pathogenesis, diagnosis, treatment, and prognosis of high-grade glioma with extracranial metastases. A retrospective analysis of the clinical features of two cases of malignant glioma, including metastatic sites, pathological data, and treatment methods, and a literature...

Paeoniflorin suppresses pancreatic cancer cell growth by upregulating HTRA3 expression

Paeoniflorin suppresses pancreatic cancer cell growth by upregulating HTRA3 expression Yuejun Li,1,* Lili Gong,2,* Ruili Qi,2 Qian Sun,2 Xinxin Xia,3 Haihui He,1 Jianshu Ren,1 Ouning Zhu,1 Debin ... formation assay; microar- - open access to scientific and medical research O r i g i n a l r e s e a r c h Yuejun li 1,* lili gong 2,* ruili Qi 2 Qian sun 2 *These authors contributed equally to this

Design and Achievement of User Interface Automation Testing of Linux Based on Element Tree of DogTail

As Linux gets more popular around the world, the advantage of the open source on software makes people do automated UI test by unified testing framework. UI software testing can guarantee the rationality of User Interface of Linux and accuracy of the UI’s widgets. In order to set free from fuzzy and repeated manual testing, and improve efficiency, this paper achieves automation...

NFATc1 phosphorylation by DYRK1A increases its protein stability

NFATs are transcription factors involved in immune activation and tumor progression. Previous reports showed that DYRK1A suppressed NFATc2 transcriptional activity through phosphorylation. Nonetheless, our results showed that DYRK1A increased NFATc1/αA protein level and subsequent transcriptional activity. DYRK1A phosphorylation of NFATc1/αA at S261, S278, S403 and S409...

The Inhibitory Effect of Pseudolaric Acid B on Gastric Cancer and Multidrug Resistance via Cox-2/PKC-α/P-gp Pathway

Aim To investigate the inhibitory effect of pseudolaric acid B on subcutaneous xenografts of human gastric adenocarcinoma and the underlying molecular mechanisms involved in its multidrug resistance. Methods Human gastric adenocarcinoma SGC7901 cells and drug-resistant SGC7901/ADR cells were injected into nude mice to establish a subcutaneous xenograft model. The effects of...

Effect of Dispersion Method on Stability and Dielectric Strength of Transformer Oil-Based TiO2 Nanofluids

Dispersion stability of nanoparticles in the liquid media is of great importance to the utilization in practice. This study aims to investigate the effects of mechanical dispersion method on the dispersibility of functionalized TiO2 nanoparticles in the transformer oil. Dispersion methods, including stirring, ultrasonic bath, and probe processes, were systematically tested to...

Effects of Thickness of a Low-Temperature Buffer and Impurity Incorporation on the Characteristics of Nitrogen-polar GaN

In this study, effects of the thickness of a low temperature (LT) buffer and impurity incorporation on the characteristics of Nitrogen (N)-polar GaN are investigated. By using either a nitridation or thermal annealing step before the deposition of a LT buffer, three N-polar GaN samples with different thicknesses of LT buffer and different impurity incorporations are prepared. It...

Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library

Background Polysaccharides often are necessary components of bacterial biofilms and capsules. Production of these biopolymers constitutes a drain on key components in the central carbon metabolism, but so far little is known concerning if and how the cells divide their resources between cell growth and production of exopolysaccharides. Alginate is an industrially important linear...

User controllable anisotropic shape distribution on 3D meshes

research interests include computer graphics, virtual reality, and GPU computing. Qian Sun received her Ph.D. degree in computer science from Nanyang Technological University, Singapore. She is currently a

Disparities between Ophthalmologists and Patients in Estimating Quality of Life Associated with Diabetic Retinopathy

Background This study aimed to evaluate and compare the utility values associated with diabetic retinopathy (DR) in a sample of Chinese patients and ophthalmologists. Methods Utility values were evaluated by both the time trade-off (TTO) and rating scale (RS) methods for 109 eligible patients with DR and 2 experienced ophthalmologists. Patients were stratified by Snellen best...

Market Confidence Predicts Stock Price: Beyond Supply and Demand

Stock price prediction is an important and challenging problem in stock market analysis. Existing prediction methods either exploit autocorrelation of stock price and its correlation with the supply and demand of stock, or explore predictive indictors exogenous to stock market. In this paper, using transaction record of stocks with identifier of traders, we introduce an index to...

Effects of Preparation Conditions on the CuInS2 Films Prepared by One-Step Electrodeposition Method

CuInS2 thin films were prepared onto indium tin oxide (ITO) substrates by sulfurization of electrodeposited CuxInySz precursor films under S atmosphere. The influences of deposition potential, Cu2

Evaluation of Sulfadiazine Degradation in Three Newly Isolated Pure Bacterial Cultures

This study is aimed to assess the biodegradation of sulfadiazine (SDZ) and characterization of heavy metal resistance in three pure bacterial cultures and also their chemotactic response towards 2-aminopyrimidine. The bacterial cultures were isolated from pig manure, activated sludge and sediment samples, by enrichment technique on SDZ (6 mg L-1). Based on the 16S rRNA gene...

Estimating PM2.5 Concentrations in Xi'an City Using a Generalized Additive Model with Multi-Source Monitoring Data

Particulate matter with an aerodynamic diameter <2.5 μm (PM2.5) represents a severe environmental problem and is of negative impact on human health. Xi'an City, with a population of 6.5 million, is among the highest concentrations of PM2.5 in China. In 2013, in total, there were 191 days in Xi’an City on which PM2.5 concentrations were greater than 100 μg/m3. Recently, a few...

Dendritic Na+ spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons

Synaptic inputs from different brain areas are often targeted to distinct regions of neuronal dendritic arbors. Inputs to proximal dendrites usually produce large somatic EPSPs that efficiently trigger action potential (AP) output, whereas inputs to distal dendrites are greatly attenuated and may largely modulate AP output. In contrast to most other cortical and hippocampal...

Rice black streaked dwarf virus P7-2 forms a SCF complex through binding to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the gibberellin pathway

As a core subunit of the SCF complex that promotes protein degradation through the 26S proteasome, S-phase kinase-associated protein 1 (SKP1) plays important roles in multiple cellular processes in eukaryotes, including gibberellin (GA), jasmonate, ethylene, auxin and light responses. P7-2 encoded by Rice black streaked dwarf virus (RBSDV), a devastating viral pathogen that...

Minimal residual disease- and graft-vs.-host disease-guided multiple consolidation chemotherapy and donor lymphocyte infusion prevent second acute leukemia relapse after allotransplant

Background Persons with acute leukemia relapsing after allotransplant and who respond to anti-leukemia interventions are at high risk of a second relapse. We studied the impact of minimal residual disease (MRD)- and graft-vs.-host disease (GvHD)-guided multiple consolidation chemotherapy and donor lymphocyte infusions (DLIs) to prevent second relapse in patients with acute...