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115 papers found.
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Exploring NCATS in-house biomedical data for evidence-based drug repurposing

://ncats.nih.gov/translator). Author Contributions Conceptualization: Ruili Huang, Yanji Xu, Ewy A. Mathe´, Qian Zhu. Data curation: Fang Liu, Chloe Chen. Investigation: Qian Zhu. Methodology: Fang Liu, Ruili ... Huang, Qian Zhu. Project administration: Qian Zhu. Resources: Qian Zhu. Supervision: Qian Zhu. Validation: Fang Liu, Andrew Patt, Qian Zhu. Writing – original draft: Fang Liu, Qian Zhu. Writing

Supporting Fault-Tolerance for Time-Critical Events in Distributed Environments

Scientific Programming Supporting fault-tolerance for time-critical events in distributed environments Corresponding author: Qian Zhu 1 Department of Computer 1 0 and Gagan Agrawal Department of

Supporting Fault-Tolerance for Time-Critical Events in Distributed Environments

Scientific Programming Supporting fault-tolerance for time-critical events in distributed environments Corresponding author: Qian Zhu 1 Department of Computer 1 0 and Gagan Agrawal Department of

An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD)

The Genetic and Rare Diseases (GARD) Information Center was established by the National Institutes of Health (NIH) to provide freely accessible consumer health information on over 6500 genetic and rare diseases. As the cumulative scientific understanding and underlying evidence for these diseases have expanded over time, existing practices to generate knowledge from these...

A comparison of foot posture and walking performance in patients with mild, moderate, and severe adolescent idiopathic scoliosis

: Ming Zhang. Investigation: Qianqin Hong, Dan Wang. Methodology: Jie Chen, Qian Zhu, Chong Zhang. Project administration: Feilong Zhu, Ming Zhang. Validation: Wei Chen, Ming Zhang. Visualization: Wei

Supporting Fault-Tolerance for Time-Critical Events in Distributed Environments

Scientific Programming Supporting fault-tolerance for time-critical events in distributed environments Corresponding author: Qian Zhu 1 Department of Computer 1 0 and Gagan Agrawal Department of

Supporting Fault-Tolerance for Time-Critical Events in Distributed Environments

Scientific Programming Supporting fault-tolerance for time-critical events in distributed environments Corresponding author: Qian Zhu 1 Department of Computer 1 0 and Gagan Agrawal Department of

Intrauterine growth restriction alters growth performance, plasma hormones, and small intestinal microbial communities in growing-finishing pigs

The interaction of the gut microbiota with key metabolic and physiological processes may be associated with poor growth outcomes in animals born with intrauterine growth restriction (IUGR). Growth performance, plasma hormone concentrations, and intestinal microbiota composition were analyzed in IUGR pigs and in normal birth weight (NBW) pigs when the NBW pigs reached 25, 50, and...

Current understanding of extrachromosomal circular DNA in cancer pathogenesis and therapeutic resistance

, Guijie Guo, Jinzhou Huang, Ming Gao & Qian Zhu Department of Pathology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China Zhijie Xu National Clinical Research Center for ... PubMed Google Scholar Ming Gao View author publications You can also search for this author in PubMed Google Scholar Qian Zhu View author publications You can also search for this author in

Photonic Time-Stretch Technology with Prismatic Pulse Dispersion towards Fast Real-Time Measurements

Photonics photonics Lei Yang Hui Chen Jun Ma Qian Zhu Tong Yang Hongbo Xie Photonic time-stretch (PTS) technology enables revolutionary technical breakthroughs in ultrafast electronic and

Cortical GABAergic Interneuron/Progenitor Transplantation as a Novel Therapy for Intractable Epilepsy

Epilepsy is a severe neurological disease affecting more than 70 million people worldwide that is characterized by unpredictable and abnormal electrical discharges resulting in recurrent seizures. Although antiepileptic drugs (AEDs) are the mainstay of epilepsy treatment for seizure control, about one third of patients with epilepsy suffer from intractable seizures that are...

TIP60 recruits SUV39H1 to chromatin to maintain heterochromatin genome stability and resist hydrogen peroxide-induced cytotoxicity

Tat interacting protein 60 (TIP60) is a histone acetyltransferase involved in chromatin remodeling and the DNA damage response. However, the role of TIP60 in maintaining genome stability is poorly understood. Here, we show that TIP60 can directly interact with suppressor of variegation 3–9 homologue 1 (SUV39H1), a methyltransferase that is responsible for histone H3 tri...

Accurate estimation of cell-type composition from gene expression data

The rapid development of single-cell transcriptomic technologies has helped uncover the cellular heterogeneity within cell populations. However, bulk RNA-seq continues to be the main workhorse for quantifying gene expression levels due to technical simplicity and low cost. To most effectively extract information from bulk data given the new knowledge gained from single-cell...

Identification and validation of major QTLs associated with low seed coat deficiency of natto soybean seeds ( Glycine max L.)

Two major QTLs associated with low seed coat deficiency of soybean seeds were identified in two biparental populations, and three SNP markers were validated to assist low-SCD natto soybean breeding selection. Soybean seed coat deficiency (SCD), known as seed coat cracking during soaking in the natto production process, is problematic because split or broken beans clog production...

HLA-A and HLA-DRB1 may play a unique role in ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

, Shanghai, 200030, China Xiaoya Zhao, Qian Zhu, Guiling Liang, Wei Xia, Xiaoqing He, Chenfeng Zhu, Hang Qi & Jian Zhang Department of Pathology, International Peace Maternity and Child Health Hospital ... also search for this author in PubMed Google Scholar Qian Zhu View author publications You can also search for this author in PubMed Google Scholar Guiling Liang View author publications You

Peripheral nerve field stimulation to the preauricular area for intractable chronic migraine: a case report

Michael Ueberall Yi-Fan Li,1,2 Peng Mao,2 Qian Zhu,2 Bo-Tao Liu,2 Bi-Fa Fan2 1Department of Graduate School, Beijing University of Chinese Medicine, Beijing 100029, People’s Republic

Nonlinear Resonance Responses of Electromechanical Integrated Magnetic Gear System

Nonlinear differential equations for an electromechanical integrated magnetic gear (EIMG) system are developed by considering the nonlinearity in the magnetic force of the system components. Expressions for the main resonances and superharmonic resonances are obtained for output wave frequencies close to the natural frequency and half the natural frequency of the derived EIMG...