contributions from all the authors. All authors have given approval to the final version of the manuscript. Authors’ Information Qing-Yang Xu, Da-Xing Yuan, and Hao-Ran Mu are graduate students major in
Liver fibrosis is characterized by the transdifferentiation of hepatic stellate cells (HSCs) to myofibroblasts and poor response to treatment. This can be attributed to the myofibroblast-specific resistance to phenotype reversal. In this study, we complemented miR-16 into miR-16-deficient myofibroblasts and analyzed the global role of miR-16 using transcriptome profiling and...