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Canonical correlation analysis (CCA) of anthropometric parameters and physical activities with blood lipids

Anthropometric parameters and physical activities are significant factors influencing lipid levels, but few research have demonstrated the effect of amount of activities on lipid levels. Our research analyzed and explored this relationships. A multi-stage stratified sampling method was used to select the investigation subjects in Hubei, China. A questionnaire survey, physical...

Diabetic Women Suffer More Years of Life Lost Than Diabetic Men

Zhi-Jiang Zhang, Genming Zhao, Chuanhua Yu, Yongyi Bi, Qingjun Zhang, and Yiqing Song declare that they have no conflict of interests. References V. Harjutsalo, C. Maric-Bilkan, C. Forsblom, L

Decreased FOXD3 Expression Is Associated with Poor Prognosis in Patients with High-Grade Gliomas

Background The transcription factor forkhead box D3 (FOXD3) plays important roles in the development of neural crest and has been shown to suppress the development of various cancers. However, the expression and its potential biological roles of FOXD3 in high-grade gliomas (HGGs) remain unknown. Methods The mRNA and protein expression levels of FOXD3 were examined using real-time...

Reduced Risk of Lung Cancer With Metformin Therapy in Diabetic Patients: A Systematic Review and Meta-Analysis

, Shiyue Li , Yi Guo); Global Health Institute, Wuhan University , Wuhan, China (Zhi-Jiang Zhang, Yongyi Bi, Shiyue Li , Yi Guo); Hubei Center for Disease Prevention and Control , Wuhan , China ( Qingjun ... Zhang); Department of Epidemiology 1 School of Public Health, Fudan University , Shanghai , China ( Genming Zhao); and Cancer Center, Renmin Hospital, Wuhan University , Wuhan , China ( Qibin Song

Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure

SIRT1, a mammalian ortholog of yeast silent information regulator 2 (Sir2), is an NAD+-dependent protein deacetylase that plays a critical role in the regulation of vascular function. The current study aims to investigate the functional significance of deacetylase activity of SIRT1 in heart. Here we show that the early postnatal hearts expressed the highest level of SIRT1...

Chronic disease mortality in rural and urban residents in Hubei Province, China, 2008–2010

Background Chronic non-communicable diseases have become the major cause of death in China. This study describes and compares chronic disease mortality between urban and rural residents in Hubei Province, central China. Methods Death records of all individuals aged 15 years and over who died from 2008 through 2010 in Hubei were obtained from the Disease Surveillance Points system...

The gap in injury mortality rates between urban and rural residents of Hubei province, China

Background Injury is a growing public health concern in China. Injury death rates are often higher in rural areas than in urban areas in general. The objective of this study is to compare the injury mortality rates in urban and rural residents in Hubei Province in central China by age, sex and mechanism of injury. Methods Using data from the Disease Surveillance Points (DSP...