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69 papers found.
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Augmented superfield approach to gauge-invariant massive 2-form theory

. C 74 , 3025 ( 2014 ) 35. A. Shukla , S. Krishna , R.P. Malik , Int. J. Mod. Phys. A 29 , 1450183 ( 2014 ) 36. S. Gupta , R. Kumar , Int. J. Theor. Phys . 55 , 927 ( 2016 ) 37. S. Gupta , R. Kumar ... , 5095 ( 2003 ) 49. S. Gupta , R. Kumar , R.P. Malik , Eur. Phys. J. C 70 , 491 ( 2010 ) 50. S. Krishna , A. Shukla , R.P. Malik , Int. J. Mod. Phys. A 26 , 4419 ( 2011 ) 51. R. Kumar , R.P. Malik , Eur

Denudation of human amniotic membrane by a novel process and its characterisations for biomedical applications

This study was aimed to investigate the suitability of a modified method to get decellularised human amniotic membrane (DHAM). The obtained membrane was subjected to physico-chemical and biological evaluations to validate its potential for biomedical applications. The human amniotic membrane was processed with detergent and alkali followed by enzymatic treatments. Hematoxylin and ...

Prediction of Certain Well-Characterized Domains of Known Functions within the PE and PPE Proteins of Mycobacteria

The PE and PPE protein family are unique to mycobacteria. Though the complete genome sequences for over 500 M. tuberculosis strains and mycobacterial species are available, few PE and PPE proteins have been structurally and functionally characterized. We have therefore used bioinformatics tools to characterize the structure and function of these proteins. We selected representative ...

Experimental study of an inclined flat plate-type solar water distillation system

Flat plate-type solar water distillation (FPSWD) is having importance for providing hot water and drinking water simultaneously to households in rural areas or small community/hotels. It utilizes solar radiation to heat the water, produce fresh water out of the saline or brackish water, and also produce hot water. The paper is focused on field performance of inclined FPSWD for ...

Defining the genetic basis of early onset hereditary spastic paraplegia using whole genome sequencing

Kishore R Kumar , G.M. Wali, Mahesh Kamate, Tony Roscioli, Carolyn 2 Department of Medical Genetics, Sydney Children's Hospital , Randwick , Australia 3 St Vincent's Clinical School, University of New South

6-Thioguanine and zebularine down-regulate DNMT1 and globally demethylate canine malignant lymphoid cells

Background The antimetabolite 6-thioguanine (6-TG) has been used to treat both human and canine lymphoid malignancies. 6-TG has been shown to be epigenetically active as a demethylating agent in a human lymphoma cell line, causing downregulation of DNA methyltransferase 1 (DNMT1) through ubiquitin-targeted degradation. Zebularine (Zeb), a similar cytidine analog, also has ...

Bacterial Quorum Sensing Molecule N-3-Oxo-Dodecanoyl-L-Homoserine Lactone Causes Direct Cytotoxicity and Reduced Cell Motility in Human Pancreatic Carcinoma Cells

In spite of chemotherapeutic and surgical advances, pancreatic cancer continues to have a dismal prognosis. Metastasis due to tumor cell migration remains the most critical challenge in treating pancreatic cancer, and conventional chemotherapy is rarely curative. In the quest for more novel molecules to fight this disease, we tested the hypothesis that the Pseudomonas aeruginosa ...

Molecular evidence of Erysiphe pisi on pea and E. trifoliorum on white clover in northeast India

Phylogenetic analysis was conducted using the ITS region of nrDNA for confirmation of the identity of anamorphic powdery mildew pathogens on pea and white clover. Maximum likelihood and bayesian analysis clearly indicated that the pathogen responsible for powdery mildew on pea in northeast India is Erysiphe pisi rather than E. trifoliorum (syn. E. trifolii) which has been reported ...

Real-Time Sequence-Validated Loop-Mediated Isothermal Amplification Assays for Detection of Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

The Middle East respiratory syndrome coronavirus (MERS-CoV), an emerging human coronavirus, causes severe acute respiratory illness with a 35% mortality rate. In light of the recent surge in reported infections we have developed asymmetric five-primer reverse transcription loop-mediated isothermal amplification (RT-LAMP) assays for detection of MERS-CoV. Isothermal amplification ...

Portal, superior mesenteric and splenic vein thrombosis secondary to hyperhomocysteinemia with pernicious anemia: a case report

Introduction Acute portomesenteric vein thrombosis is an uncommon but serious condition with potential sequelae, such as small-bowel gangrene and end-stage hepatic failure. It is known to be caused by various pro-thrombotic states, including hyperhomocysteinemia. We describe what is, to the best of our knowledge, the first reported case of concomitant thrombosis of portal, superior ...

A Versatile, Bar-Coded Nuclear Marker/Reporter for Live Cell Fluorescent and Multiplexed High Content Imaging

The screening of large numbers of compounds or siRNAs is a mainstay of both academic and pharmaceutical research. Most screens test those interventions against a single biochemical or cellular output whereas recording multiple complementary outputs may be more biologically relevant. High throughput, multi-channel fluorescence microscopy permits multiple outputs to be quantified in ...