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Search: authors:"Raf H. M. van Hoof"

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Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits

. Supporting information S1 File. Data underlying the study findings. (XLSX) Author Contributions Conceptualization: Raf H. M. van Hoof, Evelien Hermeling, Judith C. Sluimer, Julie Salzmann, Arnold P. G ... . Hoeks, JeÂroÃme Roussel, Mat J. A. P. Daemen, Harry Struijker-Boudier, Joachim E. Wildberger, Sylvia Heeneman, M. Eline Kooi. Data curation: Raf H. M. van Hoof, Evelien Hermeling, M. Eline Kooi. Formal

Dynamic Contrast-Enhanced MRI to Study Atherosclerotic Plaque Microvasculature

Rupture of a vulnerable atherosclerotic plaque of the carotid artery is an important underlying cause of clinical ischemic events, such as stroke. Abundant microvasculature has been identified as an important aspect contributing to plaque vulnerability. Plaque microvasculature can be studied non-invasively with dynamic contrast-enhanced (DCE-)MRI in animals and patients. In...

Suitability of Pharmacokinetic Models for Dynamic Contrast-Enhanced MRI of Abdominal Aortic Aneurysm Vessel Wall: A Comparison

Purpose Increased microvascularization of the abdominal aortic aneurysm (AAA) vessel wall has been related to AAA progression and rupture. The aim of this study was to compare the suitability of three pharmacokinetic models to describe AAA vessel wall enhancement using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods Patients with AAA...