Advanced search    

Search: authors:"Raffaele Marfella"

31 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Serum adiponectin levels are associated with worse cognitive function in postmenopausal women

: Pasquale De Franciscis, Michelangela Barbieri, Nicola Colacurci, Giu Formal analysis: Michelangela Barbieri, Raffaele Marfella, Maria Rosaria Rizzo. Methodology: Pasquale De Franciscis, Michelangela ... Barbieri, Stefania Leo, Anna Maria Dalise, Celestino Sardu, Maria Rosaria Rizzo. Supervision: Raffaele Marfella, Nicola Colacurci, Giuseppe Paolisso, Maria Rosaria Rizzo. Validation: Nicola Colacurci

Moderate-intensity statin therapy seems ineffective in primary cardiovascular prevention in patients with type 2 diabetes complicated by nephropathy. A multicenter prospective 8 years follow up study

Cirillo 4 Giuseppe Paolisso 5 Raffaele Marfella 5 0 Department of Internal and Experimental Medicine ' Magrassi-Lanzara', Second University of Naples , Naples , Italy 1 Unit of Nephrology, Second University

The Cytokinome Profile in Patients with Hepatocellular Carcinoma and Type 2 Diabetes

Understanding the dynamics of the complex interaction network of cytokines, defined as ‘‘cytokinome’’, can be useful to follow progression and evolution of hepatocellular carcinoma (HCC) from its early stages as well as to define therapeutic strategies. Recently we have evaluated the cytokinome profile in patients with type 2 diabetes (T2D) and/or chronic hepatitis C (CHC...

Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition

MARIA ROSARIA RIZZO PHD MICHELANGELA BARBIERI PHD RAFFAELE MARFELLA PHD GIUSEPPE PAOLISSO PHD OBJECTIVEdEvaluate the effects of two dipeptidyl peptidase-IV (DPP-4) inhibitors, sitagliptin and

Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation

Francesco Nicoletti 5 Gaetano Santulli 4 Giuseppe Paolisso 0 Raffaele Marfella 0 1 0 Department of Medical , Surgical, Neurological , Metabolic and Geriatric Sciences, Second University of Naples , Naples

Association of Genetic Variation in Adaptor Protein APPL1/APPL2 Loci with Non-Alcoholic Fatty Liver Disease

The importance of genetics and epigenetic changes in the pathogenesis of non alcoholic fatty liver disease (NAFLD) has been increasingly recognized. Adiponectin has a central role in regulating glucose and lipid metabolism and controlling inflammation in insulin-sensitive tissues and low adiponectin levels have been linked to NAFLD. APPL1 and APPL2 are adaptor proteins that...

Mediterranean Diet, Telomere Maintenance and Health Status among Elderly

Leukocyte telomere length (LTL) and rate of telomere shortening are known biomarkers of aging while, numerous studies showed that Mediterranean diet (MD) may boost longevity. We studied association between telomere length, telomerase activity and different adherence to MD and its effects on healthy status. The study was conducted in 217 elderly subjects stratified according...

Annexin A1 N-Terminal Derived Peptide Ac2-26 Stimulates Fibroblast Migration in High Glucose Conditions

Deficient wound healing in diabetic patients is very frequent, but the cellular and molecular causes are poorly defined. In this study, we have evaluated whether Annexin A1 derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions. Using normal human skin fibroblasts WS1 in low glucose (LG) or high glucose (HG) we observed the enrichment of Annexin A1...

Cytokinome Profile of Patients with Type 2 Diabetes and/or Chronic Hepatitis C Infection

Both type 2 diabetes (T2D) and chronic hepatitis C (CHC) infection are associated with increased risk of developing hepatocellular carcinoma (HCC). Cytokines are known to play an important role not only in the mechanisms of insulin resistance and glucose disposal defects but also in the pathological processes occurring in the liver during viral infection. We evaluated the serum...

High cardiovascular risk in patients with Type 2 diabetic nephropathy: the predictive role of albuminuria and glomerular filtration rate. The NID-2 Prospective Cohort Study

Background. In Type 2 diabetic patients, clinical diagnosis of diabetic nephropathy (DN) is generally based on the concomitant presence of abnormal albuminuria and severe retinopathy. In this high-risk population, cardiovascular (CV) outcome has never been evaluated.

Relationships Between Daily Acute Glucose Fluctuations and Cognitive Performance Among Aged Type 2 Diabetic Patients

MARIA ROSARIA RIZZO PHD RAFFAELE MARFELLA PHD MICHELANGELA BARBIERI PHD VIRGINIA BOCCARDI FRANCESCO VESTINI BIAGIO LETTIERI SILVESTRO CANONICO GIUSEPPE PAOLISSO PHD OBJECTIVE - The mean amplitude of

Plasma Interleukin-18 Concentrations Are Elevated in Type 2 Diabetes

, MD RAFFAELE MARFELLA, MD, PHD DARIO GIUGLIANO, MD, PHD References 1. Aso Y, Okumura K-I, Takebayashi K, Wakabayashi S, Inukai T: Relationships of plasma interleukin-18

Bariatric Surgery Reduces Oxidative Stress by Blunting 24-h Acute Glucose Fluctuations in Type 2 Diabetic Obese Patients

RAFFAELE MARFELLA PHD MICHELANGELA BARBIERI PHD ROBERTO RUGGIERO MARIA ROSARIA RIZZO PHD RODOLFO GRELLA PHD ANNA LICIA MOZZILLO LUDOVICO DOCIMO GIUSEPPE PAOLISSO PHD OBJECTIVE We evaluated the

Stress Hyperglycemia, Inflammation, and Cardiovascular Events

ESPOSITO, MD RAFFAELE MARFELLA, MD, PHD DARIO GIUGLIANO, MD, PHD From the Department of Geriatrics and Metabolic Diseases, Cardiovascular Research Center, Second University of Naples, Naples, Italy

Effects of PPARs Agonists on Cardiac Metabolism in Littermate and Cardiomyocyte-Specific PPAR-γ –Knockout (CM-PGKO) Mice

Understanding the molecular regulatory mechanisms controlling for myocardial lipid metabolism is of critical importance for the development of new therapeutic strategies for heart diseases. The role of PPARγ and thiazolidinediones in regulation of myocardial lipid metabolism is controversial. The aim of our study was to assess the role of PPARγ on myocardial lipid metabolism and...

The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes

We have reviewed the impact of the ubiquitin proteasome system (UPS) on atherosclerosis progression of diabetic patients. A puzzle of many pieces of evidence suggests that UPS, in addition to its role in the removal of damaged proteins, is involved in a number of biological processes including inflammation, proliferation and apoptosis, all of which constitute important...