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Serum adiponectin levels are associated with worse cognitive function in postmenopausal women

: Pasquale De Franciscis, Michelangela Barbieri, Nicola Colacurci, Giu Formal analysis: Michelangela Barbieri, Raffaele Marfella, Maria Rosaria Rizzo. Methodology: Pasquale De Franciscis, Michelangela ... Barbieri, Stefania Leo, Anna Maria Dalise, Celestino Sardu, Maria Rosaria Rizzo. Supervision: Raffaele Marfella, Nicola Colacurci, Giuseppe Paolisso, Maria Rosaria Rizzo. Validation: Nicola Colacurci

Moderate-intensity statin therapy seems ineffective in primary cardiovascular prevention in patients with type 2 diabetes complicated by nephropathy. A multicenter prospective 8 years follow up study

Cirillo 4 Giuseppe Paolisso 5 Raffaele Marfella 5 0 Department of Internal and Experimental Medicine ' Magrassi-Lanzara', Second University of Naples , Naples , Italy 1 Unit of Nephrology, Second University

Cardiac Resynchronization Therapy Outcomes in Type 2 Diabetic Patients: Role of MicroRNA Changes

Raffaele Marfella Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, 80138 Naples, Italy Received 19 March 2015; Accepted 27 March 2015 Academic ... authors declare that there is not conflict of interests. Authors’ Contribution Celestino Sardu has edited and written the paper. Raffaele Marfella and Giuseppe Paolisso have reviewed, edited, and approved

Awaking Blood Pressure Surge and Progression to Microalbuminuria in Type 2 Normotensive Diabetic Patients

Rizzo researched data. Raffaele Marfella wrote the paper and researched data. Giuseppe Paolisso, Pasquale Paolisso, Angela Abbatecola, Nicola Angelico, and Celestino Sardu reviewed, edited, and wrote the ... paper. Michelangela Barbieri and Ilaria Fava researched data and contributed discussion. Acknowledgment The authors would like to thank the guarantor Professor Raffaele Marfella. References J. R

The Cytokinome Profile in Patients with Hepatocellular Carcinoma and Type 2 Diabetes

Understanding the dynamics of the complex interaction network of cytokines, defined as ‘‘cytokinome’’, can be useful to follow progression and evolution of hepatocellular carcinoma (HCC) from its early stages as well as to define therapeutic strategies. Recently we have evaluated the cytokinome profile in patients with type 2 diabetes (T2D) and/or chronic hepatitis C (CHC...

Reduction of Oxidative Stress and Inflammation by Blunting Daily Acute Glucose Fluctuations in Patients With Type 2 Diabetes: Role of dipeptidyl peptidase-IV inhibition

MARIA ROSARIA RIZZO PHD MICHELANGELA BARBIERI PHD RAFFAELE MARFELLA PHD GIUSEPPE PAOLISSO PHD OBJECTIVEdEvaluate the effects of two dipeptidyl peptidase-IV (DPP-4) inhibitors, sitagliptin and

Association of Genetic Variation in Adaptor Protein APPL1/APPL2 Loci with Non-Alcoholic Fatty Liver Disease

The importance of genetics and epigenetic changes in the pathogenesis of non alcoholic fatty liver disease (NAFLD) has been increasingly recognized. Adiponectin has a central role in regulating glucose and lipid metabolism and controlling inflammation in insulin-sensitive tissues and low adiponectin levels have been linked to NAFLD. APPL1 and APPL2 are adaptor proteins that...

Metabolic syndrome is associated with a poor outcome in patients affected by outflow tract premature ventricular contractions treated by catheter ablation

Francesco Nicoletti 5 Gaetano Santulli 4 Giuseppe Paolisso 0 Raffaele Marfella 0 1 0 Department of Medical , Surgical, Neurological , Metabolic and Geriatric Sciences, Second University of Naples , Naples

Mediterranean Diet, Telomere Maintenance and Health Status among Elderly

Leukocyte telomere length (LTL) and rate of telomere shortening are known biomarkers of aging while, numerous studies showed that Mediterranean diet (MD) may boost longevity. We studied association between telomere length, telomerase activity and different adherence to MD and its effects on healthy status. The study was conducted in 217 elderly subjects stratified according...

Annexin A1 N-Terminal Derived Peptide Ac2-26 Stimulates Fibroblast Migration in High Glucose Conditions

Deficient wound healing in diabetic patients is very frequent, but the cellular and molecular causes are poorly defined. In this study, we have evaluated whether Annexin A1 derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions. Using normal human skin fibroblasts WS1 in low glucose (LG) or high glucose (HG) we observed the enrichment of Annexin A1...

Cytokinome Profile of Patients with Type 2 Diabetes and/or Chronic Hepatitis C Infection

Both type 2 diabetes (T2D) and chronic hepatitis C (CHC) infection are associated with increased risk of developing hepatocellular carcinoma (HCC). Cytokines are known to play an important role not only in the mechanisms of insulin resistance and glucose disposal defects but also in the pathological processes occurring in the liver during viral infection. We evaluated the serum...

High cardiovascular risk in patients with Type 2 diabetic nephropathy: the predictive role of albuminuria and glomerular filtration rate. The NID-2 Prospective Cohort Study

Background. In Type 2 diabetic patients, clinical diagnosis of diabetic nephropathy (DN) is generally based on the concomitant presence of abnormal albuminuria and severe retinopathy. In this high-risk population, cardiovascular (CV) outcome has never been evaluated.

Relationships Between Daily Acute Glucose Fluctuations and Cognitive Performance Among Aged Type 2 Diabetic Patients

MARIA ROSARIA RIZZO PHD RAFFAELE MARFELLA PHD MICHELANGELA BARBIERI PHD VIRGINIA BOCCARDI FRANCESCO VESTINI BIAGIO LETTIERI SILVESTRO CANONICO GIUSEPPE PAOLISSO PHD OBJECTIVE - The mean amplitude of

Plasma Interleukin-18 Concentrations Are Elevated in Type 2 Diabetes

, MD RAFFAELE MARFELLA, MD, PHD DARIO GIUGLIANO, MD, PHD References 1. Aso Y, Okumura K-I, Takebayashi K, Wakabayashi S, Inukai T: Relationships of plasma interleukin-18

Dipeptidyl Peptidase 4 Inhibition May Facilitate Healing of Chronic Foot Ulcers in Patients with Type 2 Diabetes

; Accepted 12 September 2012 Academic Editor: N. Cameron Copyright © 2012 Raffaele Marfella et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Bariatric Surgery Reduces Oxidative Stress by Blunting 24-h Acute Glucose Fluctuations in Type 2 Diabetic Obese Patients

RAFFAELE MARFELLA PHD MICHELANGELA BARBIERI PHD ROBERTO RUGGIERO MARIA ROSARIA RIZZO PHD RODOLFO GRELLA PHD ANNA LICIA MOZZILLO LUDOVICO DOCIMO GIUSEPPE PAOLISSO PHD OBJECTIVE We evaluated the

Stress Hyperglycemia, Inflammation, and Cardiovascular Events

ESPOSITO, MD RAFFAELE MARFELLA, MD, PHD DARIO GIUGLIANO, MD, PHD From the Department of Geriatrics and Metabolic Diseases, Cardiovascular Research Center, Second University of Naples, Naples, Italy