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Synthesis and characterisation of zinc oxide nanoparticles using terpenoid fractions of Andrographis paniculata leaves

Zinc oxide (ZnO) nanoparticles have been widely employed for various pharmacological applications. Several approaches were tried to synthesize ZnO nanoparticles. In this study, ZnO nanoparticles were biosynthesized using terpenoid (TAP) fractions isolated from Andrographis paniculata leaves. Subsequently, the ZnNO3 (0.1 N) is treated with the isolated TAP fractions to biosynthesize ...

Rev1 is a base excision repair enzyme with 5′-deoxyribose phosphate lyase activity

Rev1 is a member of the Y-family of DNA polymerases and is known for its deoxycytidyl transferase activity that incorporates dCMP into DNA and its ability to function as a scaffold factor for other Y-family polymerases in translesion bypass events. Rev1 also is involved in mutagenic processes during somatic hypermutation of immunoglobulin genes. In light of the mutation pattern ...

Linalool prevents oxidative stress activated protein kinases in single UVB-exposed human skin cells

homeostasis by the skin's neuroendocrine system . Adv Anat Embryol Cell Biol . 2012 ; 212 : 1± 115 . 5. Agilan B , Rajendra Prasad N , Kanimozhi G , Karthikeyan R , Ganesan M , Mohana S , et al. Caffeic Acid ... strategies with Phytochemicals . Antioxidants . 2015 ; 4 : 248 ± 268 . https://doi.org/10.3390/antiox4020248 PMID: 26783703 9. Ramachandran S , Rajendra Prasad N , Pugalendi KV , Menon VP . Modulation of UVB

Prevalence and risk factors of diabetes in a large community-based study in North India: results from a STEPS survey in Punjab, India

Aims India is the diabetes capital with home to 69.1 million people with DM, the second highest number of cases after China. Recent epidemiological evidence indicates a rising DM epidemic across all classes, both affluent and the poor in India. This article reports on the prevalence of diabetes and pre-diabetes in the North Indian state of Punjab as part of a large household NCD ...

Green solvents and technologies for oil extraction from oilseeds

Oilseeds are crucial for the nutritional security of the global population. The conventional technology used for oil extraction from oilseeds is by solvent extraction. In solvent extraction, n-hexane is used as a solvent for its attributes such as simple recovery, non-polar nature, low latent heat of vaporization (330 kJ/kg) and high selectivity to solvents. However, usage of ...

Mitigating Financial Burden of Tuberculosis through Active Case Finding Targeting Household and Neighbourhood Contacts in Cambodia

Research Unit THAILAND Fukushi Morishita 0 Rajendra-Prasad Yadav Mao Tan Eang Saly Saint Nobuyuki Nishikiori 0 0 World Health Organization Regional Office for the Western Pacific, Manila, Philippines, 2

A systematic review: effectiveness of mass media campaigns for reducing alcohol-impaired driving and alcohol-related crashes

Background Mass media campaigns have long been used as a tool for promoting public health. In the past decade, the growth of social media has allowed more diverse options for mass media campaigns. This systematic review was conducted to assess newer evidence from quantitative studies on the effectiveness of mass media campaigns for reducing alcohol-impaired driving (AID) and ...

Bringing state-of-the-art diagnostics to vulnerable populations: The use of a mobile screening unit in active case finding for tuberculosis in Palawan, the Philippines

Background Globally, case detection of tuberculosis (TB) has stabilized in recent years. Active case finding (ACF) has regained an increased attention as a complementary strategy to fill the case detection gap. In the Philippines, the DetecTB project implemented an innovative ACF strategy that offered a one-stop diagnostic service with a mobile unit equipped with enhanced ...

Increased Case Notification through Active Case Finding of Tuberculosis among Household and Neighbourhood Contacts in Cambodia

Background Globally, there has been growing evidence that suggests the effectiveness of active case finding (ACF) for tuberculosis (TB) in high-risk populations. However, the evidence is still insufficient as to whether ACF increases case notification beyond what is reported in the routine passive case finding (PCF). In Cambodia, National TB Control Programme has conducted ...

Mammalian Base Excision Repair: Functional Partnership between PARP-1 and APE1 in AP-Site Repair

The apurinic/apyrimidinic- (AP-) site in genomic DNA arises through spontaneous base loss and base removal by DNA glycosylases and is considered an abundant DNA lesion in mammalian cells. The base excision repair (BER) pathway repairs the AP-site lesion by excising and replacing the site with a normal nucleotide via template directed gap-filling DNA synthesis. The BER pathway is ...

Association of Cord Blood Levels of Lead, Arsenic, and Zinc and Home Environment with Children Neurodevelopment at 36 Months Living in Chitwan Valley, Nepal

Background Inconsistent results continue to be reported from studies linking low-level prenatal lead exposure and child development. Because of limited earlier epidemiological studies with birth cohort follow up design, it still remains inconclusive that either the associations of cord blood level of toxic, and essential elements, and postnatal raising environment on ...

Complementation of aprataxin deficiency by base excision repair enzymes

Abortive ligation during base excision repair (BER) leads to blocked repair intermediates containing a 5′-adenylated-deoxyribose phosphate (5′-AMP-dRP) group. Aprataxin (APTX) is able to remove the AMP group allowing repair to proceed. Earlier results had indicated that purified DNA polymerase β (pol β) removes the entire 5′-AMP-dRP group through its lyase activity and flap ...

TiO2 photoanode sensitized with nanocrystalline Bi2S3: the effect of sensitization time and annealing on its photovoltaic performance

; Wang et al. 2012; Rajendra Prasad et al. 2013; Mane et al. 2014). Semiconductor-sensitized solar cells are excitonic solar cells that are architecturally similar to dye-sensitized solar cells (DSSC) but ... Rajalakshmi PU , Oommen R , Sanjeeviraja C ( 2013 ) Improved photoelectrochemical performance of (Bi1-xSbx)2S3 photoanodes . Thin Solid Films 531 : 76 - 80 Rajendra Prasad MB , Deena S , Rajesh Ch , Pandit

Zinc Fortification of Oat Grains Through Zinc Fertilisation

Yashbir Singh Shivay 0 Rajendra Prasad 0 Madan Pal 0 0 Y. S. Shivay (&) R. Prasad M. Pal Division of Agronomy, Indian Agricultural Research Institute , New Delhi 110 012, India A two-year study at ... . Rajendra Prasad is grateful to the Indian National Science Academy for granting him INSA Honorary Scientist and Indian Agricultural Research Institute for awarding him Adjunct Professor Positions

Over-Expression of Telomere Binding Factors (TRF1 & TRF2) in Renal Cell Carcinoma and Their Inhibition by Using SiRNA Induce Apoptosis, Reduce Cell Proliferation and Migration Invitro

Telomere binding factors viz. TRF1 and TRF2 are a part of sheltrin complex that are present exclusively at the ends of chromosomes. These factors play an important role in maintaining chromosomal integrity at the ends. However, their status and role are not clear in renal cell carcinoma (RCC). Therefore, the present study was conducted to evaluate TRF1 and TRF2 expressions in RCC ...

Zinc Fertilization of Cereals for Increased Production and Alleviation of Zinc Malnutrition in India

Rajendra Prasad 0 Yashbir Singh Shivay 0 Dinesh Kumar 0 0 R. Prasad Y. S. Shivay (&) D. Kumar Division of Agronomy, Indian Agricultural Research Institute , New Delhi 110 012, India Zinc deficiency

An Assessment of Growth Media Enrichment on Lipid Metabolome and the Concurrent Phenotypic Properties of Candida albicans

A critical question among the researchers working on fungal lipid biology is whether the use of an enriched growth medium can affect the lipid composition of a cell and, therefore, contribute to the observed phenotypes. One presumption is that enriched medias, such as YPD (yeast extract, peptone and dextrose), are likely to contain lipids, which may homogenize with the yeast lipids ...

Comparative Lipidomics of Azole Sensitive and Resistant Clinical Isolates of Candida albicans Reveals Unexpected Diversity in Molecular Lipid Imprints

Prasad 0 Robert Alan Arkowitz, Institute of Developmental Biology and Cancer Research, France 0 Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University , New Delhi , India

Molecular Mechanisms of Action of Herbal Antifungal Alkaloid Berberine, in Candida albicans

Candida albicans causes superficial to systemic infections in immuno-compromised individuals. The concomitant use of fungistatic drugs and the lack of cidal drugs frequently result in strains that could withstand commonly used antifungals, and display multidrug resistance (MDR). In search of novel fungicidals, in this study, we have explored a plant alkaloid berberine (BER) for its ...

Comparative Lipidomics in Clinical Isolates of Candida albicans Reveal Crosstalk between Mitochondria, Cell Wall Integrity and Azole Resistance

, Cell Wall Integrity and Azole Resistance Ashutosh Singh 0 Vipin Yadav 0 Rajendra Prasad 0 Martine Bassilana, Universite de Nice-CNRS, France 0 Membrane Biology Laboratory, School of Life Sciences