In this study, we aim to investigate gene expression changes in tumor samples obtained from patients with esophageal cancer treated with calcium electroporation. Previously, local treatment with calcium electroporation has been shown to induce gene expression alterations, potentially contributing to a more tumor-hostile microenvironment. In this sub-study of a phase I clinical...
An updated checklist of faunal biodiversity of the spiders, in two norther states of India, Uttar Pradesh and Uttarakhand is presented herewith. A total of 520 species of spiders described under 236 genera belonging to 50 families were recorded in both the states of north India. The biodiversity of spiders is more in Uttar Pradesh (284 species, 146 genera, 36 families) than...
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Resistance to HER2 (ErbB2)-targeted therapy may be mediated by other members of the ErbB family. We investigated the efficacy and safety of the irreversible ErbB family blocker, afatinib, alone as first-line therapy in the advanced setting and in combination with vinorelbine or paclitaxel for those who progressed on afatinib monotherapy, in female patients with metastatic breast...
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Shock and Vibration 1070-9622 Limitations of smoothening functions for automotive vibro-impact problems Zhiwei Zhang 0 Rajendra Singh 1 Ashley R. Crowther 1 0 Wolfson School of Mechanical and
Çeşitli ekolojik habitatlarda yaşayan doğadan toplanmış Drosophila türleri arasındaki fenotipik çeşitlilik ile ilgili literatür sayısı nispeten azdır. Bu çalışmada vücut boyutu özelliklerinin yükseklik eğrileri boyunca olan uyumu ve daha yüksek yerlerde kanat morfolojisinin değişimiyle daha soğuk ortamlara ve daha düşük hava basıncına uyum sağlanması incelenmiştir. Doğadan ergin...
Çeşitli ekolojik habitatlarda yaşayan doğadan toplanmış Drosophila türleri arasındaki fenotipik çeşitlilik ile ilgili literatür sayısı nispeten azdır. Bu çalışmada vücut boyutu özelliklerinin yükseklik eğrileri boyunca olan uyumu ve daha yüksek yerlerde kanat morfolojisinin değişimiyle daha soğuk ortamlara ve daha düşük hava basıncına uyum sağlanması incelenmiştir. Doğadan ergin...
Literature concerning phenotypic variation among wild-caught drosophilids inhabiting varied ecological habitats is relatively rare. The present study explores pattern of body size traits along altitudinal gradients, and compensation to colder environments and reduced air pressure via adjustment of wing morphology at higher altitudes. Wild adult flies were collected in two...
Parry–Romberg syndrome (PRS) is characterized by progressive degeneration and atrophy of the cutaneous, subcutaneous connective tissues, muscles and bones. Classically, PRS is restricted to unilateral face but in 20% of patients may extend to other parts of the body including ipsilateral or contralateral arms, trunk and legs. We report a case of 24-year-old male who presented...
Microorganisms are a promising source of an enormous number of natural products, which have made significant contribution to almost each sphere of human, plant and veterinary life. Natural compounds obtained from microorganisms have proved their value in nutrition, agriculture and healthcare. Primary metabolites, such as amino acids, enzymes, vitamins, organic acids and alcohol...
The HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis and is an attractive target for the development of novel therapeutics. A key function of Nef is to remove the CD4 receptor from the cell surface by hijacking clathrin- and adaptor protein complex 2 (AP2)-dependent endocytosis. However, exactly how Nef does this has been elusive...
Kumar Singh Shanti Kumari Ram Sewak Singh Tomar Sourabh Karwa Rajendra Singh Raja Bahadur Singh Susheel Kumar Sarkar Madan Pal Fig 7 is incorrect. Data of the tolerant and sensitive genotypes are
BackgroundLongitudinally extensive transverse myelitis is characterized by contiguous inflammatory lesion of spinal cord involving three or more spinal segments. It is a well-recognized but rare presentation of Mycobacterium tuberculosis infection.Case descriptionWe report a case of young boy diagnosed with multiple brain tuberculomas. He was on antitubercular drugs therapy for 2...
Introduction Friedreich’s ataxia (FRDA) is the most common autosomal recessive inherited ataxia. It is characterized by onset before the age of 25 year, progressive limb and truncal ataxia, lower limb areflexia, extensor plantars, dysarthria and impaired posterior column sensations. Other important associated features are skeletal deformity, hypertrophic cardiomyopathy and...
A series of new 4-thiazolidinone derivatives was synthesized, characterized by spectral techniques, and screened for antimicrobial activity. All the compounds were evaluated against five Gram-positive bacteria, two Gram-negative bacteria, and two fungi, at concentrations of 50, 100, 200, 400, 800, and 1600 µg/mL, respectively. Minimum inhibitory concentrations of all the...