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Cardiorespiratory fitness and the metabolic syndrome: Roles of inflammation and abdominal obesity

Wedell-Neergaard, Rikke Krogh-Madsen, Bente Klarlund Pedersen, Rikke Lund, Helle Bruunsgaard. Data curation: Anne-Sophie Wedell-Neergaard. 12 / 16 Formal analysis: Anne-Sophie Wedell-Neergaard, Gitte ... -Neergaard, Rikke Krogh-Madsen, Gitte Lindved Petersen, Rikke Lund, Helle Bruunsgaard. Project administration: Anne-Sophie Wedell-Neergaard, Rikke Lund, Helle Bruunsgaard. Resources: Åse Marie Hansen, Rikke

Low fitness is associated with abdominal adiposity and low-grade inflammation independent of BMI

, Rikke Krogh-Madsen. Resources: Morten Grønbñk, Bente Klarlund Pedersen. Software: Anne-Sophie Wedell-Neergaard, Louise Eriksen. Supervision: Bente Klarlund Pedersen, Rikke Krogh-Madsen. Validation ... : Janne Tolstrup. Visualization: Anne-Sophie Wedell-Neergaard, Janne Tolstrup. Writing ± original draft: Anne-Sophie Wedell-Neergaard, Bente Klarlund Pedersen, Rikke Krogh-Madsen. Writing ± review

The incretin effect in critically ill patients: a case–control study

Introduction Patients admitted to the intensive care unit often develop hyperglycaemia, but the underlying mechanisms have not been fully described. The incretin effect is reduced in patients with type 2 diabetes. Type 2 diabetes and critical illness have phenotypical similarities, such as hyperglycaemia, insulin resistance and systemic inflammation. Previous studies have shown...

A randomized controlled trial on a multicomponent intervention for overweight school-aged children – Copenhagen, Denmark

-Larsen 0 Anders Juul Lars Bo Andersen Bente Klarlund Pedersen 0 Rikke Krogh-Madsen 0 0 Department of Infectious Diseases The Centre of Inflammation and Metabolism and the Centre for Physical Activity

GLUT4 and Glycogen Synthase Are Key Players in Bed Rest–Induced Insulin Resistance. Diabetes 2012;61:1090—1099

0 Rasmus S. Biens , Stine Ringholm, Kristian Kiilerich, Niels-Jacob Aachmann- Andersen, Rikke Krogh-Madsen, Borja Guerra, Peter Plomgaard, Gerrit van Hall, Jonas T. Treebak, Bengt Saltin, Carsten

Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia

Pernille Hojman Maria Pedersen Anders Rinnov Nielsen Rikke Krogh-Madsen Christina Yfanti Thorbjrn kerstrom Sren Nielsen Bente Klarlund Pedersen OBJECTIVE-Fibroblast growth factor-21 (FGF-21) is a

GLUT4 and Glycogen Synthase Are Key Players in Bed Rest–Induced Insulin Resistance

Rasmus S. Biens Stine Ringholm Kristian Kiilerich Niels-Jacob Aachmann-Andersen Rikke Krogh-Madsen Borja Guerra Peter Plomgaard Gerrit van Hall Jonas T. Treebak Bengt Saltin Carsten Lundby Jose A.L

Calprotectin — A Novel Marker of Obesity

Background The two inflammatory molecules, S100A8 and S100A9, form a heterodimer, calprotectin. Plasma calprotectin levels are elevated in various inflammatory disorders. We hypothesized that plasma calprotectin levels would be increased in subjects with low-grade systemic inflammation i.e. either obese subjects or subjects with type 2 diabetes. Methodology/Principal Findings...

Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation

Most lifestyle-related chronic diseases are characterized by low-grade systemic inflammation and insulin resistance. Excessive tumor necrosis factor-α (TNF-α) concentrations have been implicated in the development of insulin resistance, but direct evidence in humans is lacking. Here, we demonstrate that TNF-α infusion in healthy humans induces insulin resistance in skeletal...

Plasma YKL-40: A BMI-Independent Marker of Type 2 Diabetes

Anders R. Nielsen Christian Erikstrup Julia S. Johansen Christian P. Fischer Peter Plomgaard Rikke Krogh-Madsen Sarah Taudorf Birgitte Lindegaard Bente K. Pedersen OBJECTIVE-YKL-40 is produced by