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7 papers found.
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Clinical cure of severe, early onset preeclampsia with low molecular weight heparin therapy in primigravida with hyperreactio luteinalis and thrombophilia

Tiitinen 0 Veli-Matti Ulander 0 Risto Kaaja 0 0 Department of Obstetrics and Gynaecology, Helsinki University Central Hospital , PO Box 140, FIN-00290 HUS Helsinki , Finland 1To whom correspondence should

Do mitochondrial mutations cause recurrent miscarriage?

The cause of recurrent miscarriage (RM) can be identified in ∼50% of cases, whereas in others, unknown genetic factors are actively being sought. As mitochondrial functions, and therefore also the mitochondrial genome [mitochondrial DNA (mtDNA)], have an important role in human development, through ATP production and participation in apoptosis, we aimed to study the role of mtDNA ...

Hypoglycemia in Type 1 Diabetic Pregnancy: Role of preconception insulin aspart treatment in a randomized study

SIMON HELLER PETER DAMM DMSC HENRIETTE MERSEBACH PHD TRINE VANG SKJTH RISTO KAAJA PHD MOSHE HOD SANTIAGO DUR AN-GARCA PHD DAVID MCCANCE ELISABETH R. MATHIESEN DMSC OBJECTIVE - A recent randomized

Low-molecular-weight heparin for prevention of placenta-mediated pregnancy complications: protocol for a systematic review and individual patient data meta-analysis (AFFIRM)

Bates David Petroff Dick Bezemer 1 Marion E van Hoorn 1 Carolien NH Abheiden 1 Annalisa Perna Paulien de Jong Risto Kaaja 0 The Ottawa Hospital, Centre for Practice-Changing Research , 501 Smyth Road, Box

Progression of Retinopathy During Pregnancy in Type 1 Diabetic Women Treated With Insulin Lispro

OBJECTIVE— To evaluate the progression of retinopathy during pregnancy and postpartum in (insulin-dependent) women with type 1 diabetes treated with insulin lispro or with regular human insulin. RESEARCH DESIGN AND METHODS— A prospective open study of 69 pregnant women with diabetes was performed. A total of 36 of the women were treated with insulin lispro (lispro group) and 33 ...

Termination of pregnancy and sterilisation in women with childhood-onset type 1 diabetes

Aims/hypothesis The aim of this study was to explore the association between type 1 diabetes and reproductive health indicators in women, focusing on termination of pregnancy and sterilisation. Methods We conducted a registry-based cohort study involving 2281 women with childhood-onset type 1 diabetes, matched for age and birthplace with women without diabetes: two control ...

Variations of the Amnionless gene in recurrent spontaneous abortions

Recurrent spontaneous abortions (RSA) are estimated to affect 0.5–1% of couples trying to have a child. The causes of RSA are unknown in the majority of cases. This study aimed to determine whether homozygous mutations in the AMN gene in a fetus cause spontaneous abortions in humans, as they are known to cause spontaneous abortions in mice. The study was conducted by screening 40 ...