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9 papers found.
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SPECT quantification of myocardial blood flow: A journey of a thousand miles begins with a single step (Lao Tzu, Chinese philosopher, 604-531 BC)

1 Terrence D. Ruddy 0 0 Reprint requests: Robert A deKemp , PhD , Division of Cardiology, Cardiac Imaging, University of Ottawa Heart Institute , 40 Ruskin Street, Ottawa, ON, K1Y 4W7 , Canada 1

Lesion contrast recovery for partial-volume averaging: Quantitative correction or qualitative enhancement?

Reprint requests: Robert A. deKemp, PhD, Cardiac Imaging, Department of Medicine (Cardiology), University of Ottawa Heart Institute , 40 Ruskin Street, Room H-1215, Ottawa, ON, K1Y 4W7 , Canada 1 Cardiac

Consistent tracer administration profile improves test–retest repeatability of myocardial blood flow quantification with 82Rb dynamic PET imaging

Objectives Quantification of myocardial blood flow (MBF) and stress/rest flow reserve is used increasingly to diagnose multi-vessel coronary artery disease and micro-vascular disease with PET imaging. However, variability in the measurements may limit physician confidence to direct revascularization therapies based on specific threshold values. This study evaluated the effects of...

Myocardial blood flow quantification by Rb-82 cardiac PET/CT: A detailed reproducibility study between two semi-automatic analysis programs

Background Several analysis software packages for myocardial blood flow (MBF) quantification from cardiac PET studies exist, but they have not been compared using concordance analysis, which can characterize precision and bias separately. Reproducible measurements are needed for quantification to fully develop its clinical potential. Methods Fifty-one patients underwent dynamic...

Erratum to: Characterizing the normal range of myocardial blood flow with 82rubidium and 13N-ammonia PET imaging

Erratum to: Characterizing the normal range 82 of myocardial blood flow with rubidium 13 and N-ammonia PET imaging Jennifer M. Renaud MSc Jean N. DaSilva Rob S. B. Beanlands Robert A. deKemp PhD

Imaging atherosclerosis with hybrid [18F]fluorodeoxyglucose positron emission tomography/computed tomography imaging: What Leonardo da Vinci could not see

Prodigious efforts and landmark discoveries have led toward significant advances in our understanding of atherosclerosis. Despite significant efforts, atherosclerosis continues globally to be a leading cause of mortality and reduced quality of life. With surges in the prevalence of obesity and diabetes, atherosclerosis is expected to have an even more pronounced impact upon the...