Advanced search    

Search: authors:"Rohit Shetty"

15 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Oxidative stress induces dysregulated autophagy in corneal epithelium of keratoconus patients

. Acknowledgments We are grateful to the patients who participated in this study. Author Contributions Data curation: Rohit Shetty, Anupam Sharma, Priyanka Chevour, Kamesh Dhamodaran, Chaitra Jayadev, Rudy M. M ... Pahuja, Priyanka Chevour, Neeraja Padmajan, Kamesh Dhamodaran, Chaitra Jayadev, Rudy M. M. A. Nuijts, Jeyabalan Nallathambi. Project administration: Rudy M. M. A. Nuijts. Resources: Rohit Shetty, Natasha

The impact of dysfunctional tear films and optical aberrations on chronic migraine

Background Migraine is a multifactorial disorder with complex neuronal and vascular mechanisms that encompasses a wide clinical spectrum of symptoms, including ocular manifestations. Dry eye disease and dysfunction of ocular somatosensory pathways have been implicated in the pathogenesis. The current study investigates the association between a dysfunctional tear film and ocular...

Nanostructured scaffold as a determinant of stem cell fate

The functionality of stem cells is tightly regulated by cues from the niche, comprising both intrinsic and extrinsic cell signals. Besides chemical and growth factors, biophysical signals are important components of extrinsic signals that dictate the stem cell properties. The materials used in the fabrication of scaffolds provide the chemical cues whereas the shape of the...

Personality and uveitis

Background Psycho-immunology is an emerging branch of science which studies the interaction between the brain and the immune system. The purpose of this study is to identify the types of personality factors in patients with non-infectious uveitis and to find its association with a particular uveitic entity if any. This is a prospective, observational, case-control study of 186...

Correlation between tear fluid and serum vitamin D levels

Background Vitamin D deficiency is associated with a range of systemic diseases including ocular disorders. The objective of this study is to measure tear vitamin D levels and investigate the correlation between serum and tear vitamin D levels. Methods A total of 48 healthy volunteers without any systemic and ocular disease were recruited for this observational cohort study...

Tear biomarkers for keratoconus

Keratoconus is a progressive corneal thinning, ectatic condition, which affects vision. Recent advances in corneal topography measurements has helped advance proper diagnosis of this condition and increased research and clinical interests in the disease etiopathogenesis. Considerable progress has been achieved in understanding the progression of the disease and tear fluid has...

Author’s reply to ‘Rickettsia retinitis cases in India: a few comments’

Diagnosis of rickettsial retinitis remains presumptive when gold standard tests are not available or not done due to financial constrains. History of tick bite followed by fever with skin rash particularly in winter and spring season may point towards Rickettsiosis. The absence of scarring post resolution of rickettsial retinitis suggests inner retinal involvement in contrast to...

Rickettsial retinitis—an Indian perspective

Background Though rickettsiosis is common in India, there is paucity of rickettsial retinitis (RR) reports from India. Moreover, rickettsial sub-types and their association with retinitis have not been studied. We are reporting a case series of presumed RR with their course of the disease, visual outcome, and association with rickettsial sub-type based on Weil-Felix test...

Chikungunya and the eye: a review

Padmamalini Mahendradas 0 Kavitha Avadhani 0 Rohit Shetty 0 0 Narayana Nethralaya Post Graduate Institute of Ophthalmology , 121/C, Chord Road, Rajaji Nagar 1st 'R' Block, Bangalore 560010, India

Normative Database of Retinal Oximetry in Asian Indian Eyes

Objective To study the oxygen saturation profile in normal Asian Indian eyes. Design A cross sectional prospective study. Subjects Ninety eight consecutive patients presenting to our hospital with best corrected distance visual acuity (BCVA) of 20/20 and a normal ophthalmic examination were included in the study. Patients having any ocular or systemic disease were excluded from...

Two novel missense substitutions in the VSX1 gene: clinical and genetic analysis of families with Keratoconus from India

Background Visual system homeobox gene (VSX1) plays a major role in the early development of craniofacial and ocular tissues including cone opsin gene in the human retina. To date, few disease-causing mutations of VSX1 have been linked to familial and sporadic keratoconus (KC) in humans. In this study, we describe the clinical features and screening for VSX1 gene in families with...

Biomechanics of the Cornea Evaluated by Spectral Analysis of Waveforms from Ocular Response Analyzer and Corvis-ST

Purpose In this study, spectral analysis of the deformation signal from Corvis-ST (CoST) and reflected light intensity from ocular response analyzer (ORA) was performed to evaluate biomechanical concordance with each other. Methods The study was non-interventional, observational, cross-sectional and involved 188 eyes from 94 normal subjects. Three measurements were made on each...

Combined depth imaging of choroid in uveitis

Background Understanding the changes that occur in the choroid is of paramount importance in various uveitis entities. B-scan ultrasonography and indocyanine green angiography can be used to study choroid. Currently, spectral-domain optical coherence tomography is used as the standard noninvasive technique to study the choroid by enhanced depth imaging. Our aim was to study the...

High definition spectral domain optical coherence tomography of retinal pigment epithelial rip in a case of sympathetic ophthalmia

Background We are reporting a case of granulomatous panuveitis in the right eye following penetrating injury to the left eye. Findings A 34-year-old female was diagnosed to have sympathetic ophthalmia on treatment with systemic steroids. Vision did not improve in spite of aggressive systemic steroid therapy. On examination, patient had large retinal pigment epithelial rip nasal...