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11 papers found.
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Race-specific associations between health-related quality of life and cellular aging among adults in the United States: evidence from the National Health and Nutrition Examination Survey

Purpose Poor health-related quality of life (HRQOL) could lead to higher morbidity and mortality through telomere attrition or accelerated cellular aging. We conducted a cross-sectional analysis to examine the relationship between four dimensions of HRQOL and leukocyte telomere length (LTL) among a nationally representative sample of 3547 US adults (≥20 years) using the data from...

Obstructive sleep apnea risk and leukocyte telomere length in African Americans from the MH-GRID study

Purpose Shorter telomere length and obstructive sleep apnea are associated with increased oxidative stress and chronic inflammation, which are both considered leading causes of age-related diseases. Different forms of sleep disordered breathing have been linked to telomere length although their relationship remains uncertain. The purpose of this study was to explore the...

Association of adiponectin and socioeconomic status in African American men and women: the Jackson heart study

and by grant UH1HL073461 from the National Heart, Lung and Blood Institute. Sharon K. Davis, Ruihua Xu, Pia Riestra, Samson Y. Gebreab, Rumana J. Khan and Amadou Gaye are supported by the intramural

Association of ADIPOQ gene with type 2 diabetes and related phenotypes in African American men and women: the Jackson Heart Study

. Davis, Samson Y. Gebreab, Ruihua Xu, Pia Riestra, Rumana J. Khan and Amadou Gaye are supported by the intramural program of the National Human Genome Research Institute. Submit your next manuscript to

Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort

Health, National Center for Research Resources and by the NIH grant UH1 HL073461 provided by the National Heart, Lung and Blood Institute. Pia Riestra, Sharon K Davis, Samson Gebreab, Ruihua Xu, Rumana

Parent-offspring association of metabolic syndrome in the Framingham Heart Study

Background Metabolic syndrome (MetS) is a clustering of five metabolic risk factors including abdominal obesity, elevated blood pressure, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), and impaired fasting glucose. Few studies have fully reported the strength of clustering of these risk factors in a parent-offspring relationship. This analysis describes...

Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study

K Davis, Samson Gebreab, Ruihua Xu, Pia Riestra, and Rumana Khan are supported by the intramural program of the National Human Genome Research Institute, National Institutes of Health.Anne Sumner is

Lauren classification combined with HER2 status is a better prognostic factor in Chinese gastric cancer patients

Ruihua Xu 0 3 0 Department of Medical Oncology, Sun Yat-Sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine , 651 Dongfeng

Randomized multicenter phase III study of a modified docetaxel and cisplatin plus fluorouracil regimen compared with cisplatin and fluorouracil as first-line therapy for advanced or locally recurrent gastric cancer

docetaxel and cisplatin at 60 mg/m2 (day 1) followed by fluorouracil at 600 mg/m2/day (days Jinwan Wang and Ruihua Xu contributed equally to this work. J. Wang and R. Xu contributed equally to this work

Bevacizumab plus capecitabine and cisplatin in Chinese patients with inoperable locally advanced or metastatic gastric or gastroesophageal junction cancer: randomized, double-blind, phase III study (AVATAR study)

Background In the AVAGAST study, fluoropyrimidine and cisplatin plus bevacizumab did not significantly improve overall survival (OS) versus fluoropyrimidine and cisplatin plus placebo in patients with advanced gastric cancer. Geographic differences in efficacy were observed in AVAGAST, but the study only included 12 Chinese patients. AVATAR, a study similar in design to AVAGAST...

Primary gastric non-Hodgkin's lymphoma in Chinese patients: clinical characteristics and prognostic factors

Background Optimal management and outcome of primary gastric lymphoma (PGL) have not been well defined in the rituximab era. This study aimed to analyze the clinical characteristics, prognostic factors, and roles of different treatment modalities in Chinese patients with PGL. Methods The clinicopathological features of 83 Chinese patients with PGL were retrospectively reviewed...