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Search: authors:"Ruihao Wang"

5 papers found.
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Severity of traumatic brain injury correlates with long-term cardiovascular autonomic dysfunction

, at rest and upon standing (ANOVA with post hoc testing). Orthostatic challenge; Traumatic brain injury; Autonomic dysfunction; Differences in severity - Max J. Hilz and Ruihao Wang contributed

Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer

Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) and the underlying molecular mechanisms are not known. In the present study, during induction of radio- or chemo-resistance in NSCLC cells, dynamic analyses revealed that decreased expression of let-7 induced by irradiation or cisplatin resulted in increased expression of...

Valsalva maneuver unveils central baroreflex dysfunction with altered blood pressure control in persons with a history of mild traumatic brain injury

Background Patients with a history of mild TBI (post-mTBI-patients) have an unexplained increase in long-term mortality which might be related to central autonomic dysregulation (CAD). We investigated whether standardized baroreflex-loading, induced by a Valsalva maneuver (VM), unveils CAD in otherwise healthy post-mTBI-patients. Methods In 29 healthy persons (31.3 ± 12.2 years...

Central Autonomic Dysfunction Delays Recovery of Fingolimod Induced Heart Rate Slowing

Background In multiple sclerosis (MS) patients, Fingolimod may induce prolonged heart-rate slowing which might be caused by MS-related central autonomic lesions. Objectives To evaluate whether MS-patients with prolonged heart-rate slowing (> six hours) upon Fingolimod show cardiovascular-autonomic dysfunction before Fingolimod-initiation. Methods Before Fingolimod-initiation, we...

Optimal beam arrangement for pulmonary ventilation image-guided intensity-modulated radiotherapy for lung cancer

Background The principal aim of this study was to evaluate the feasibility of incorporating four-dimensional (4D)-computed tomography (CT)-based functional information into treatment planning and to evaluate the potential benefits of individualized beam setups to better protect lung functionality in patients with non-small cell lung cancer (NSCLC). Methods Peak-exhale and peak...