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Graphene Oxide-Based Nanocomposites Decorated with Silver Nanoparticles as an Antibacterial Agent

One of the most promising methods against drug-resistant bacteria can be surface-modified materials with biocidal nanoparticles and nanocomposites. Herein, we present a nanocomposite with silver nanoparticles (Ag-NPs) on the surface of graphene oxide (GO) as a novel multifunctional antibacterial and antifungal material. Ultrasonic technologies have been used as an effective...

Analysis of the cytotoxicity of hierarchical nanoporous graphenic carbon against human glioblastoma grade IV cells

Analysis of the cytotoxicity of hierarchical nanoporous graphenic carbon against human glioblastoma grade IV cells Sławomir Jaworski,1 Paulina Biniecka,1 Żaneta Bugajska,1 Karolina Daniluk,1 Sławomir

Interaction of different forms of graphene with chicken embryo red blood cells

, Poland 3 Sławomir Jaworski With the rapid development of graphene synthesis and functionalization approaches, graphene and its related derivatives have shown great potential in many applications in

Diamond Nanoparticles Modify Curcumin Activity: In Vitro Studies on Cancer and Normal Cells and In Ovo Studies on Chicken Embryo Model

Curcumin has been studied broadly for its wide range of biological activities, including anticancer properties. The major problem with curcumin is its poor bioavailability, which can be improved by the addition of carriers, such as diamond nanoparticles (DN). They are carbon allotropes, and are therefore biocompatible and easily taken up by cells. DN are non-toxic and have...

Long Term Influence of Carbon Nanoparticles on Health and Liver Status in Rats

Due to their excellent biocompatibility, carbon nanoparticles have been widely investigated for prospective biomedical applications. However, their impact on an organism with prolonged exposure is still not well understood. Here, we performed an experiment investigating diamond, graphene oxide and graphite nanoparticles, which were repeatedly administrated intraperitoneally into...

Biodistribution of a High Dose of Diamond, Graphite, and Graphene Oxide Nanoparticles After Multiple Intraperitoneal Injections in Rats

Carbon nanoparticles have recently drawn intense attention in biomedical applications. Hence, there is a need for further in vivo investigations of their biocompatibility and biodistribution via various exposure routes. We hypothesized that intraperitoneally injected diamond, graphite, and graphene oxide nanoparticles may have different biodistribution and exert different effects...

Structural damage of chicken red blood cells exposed to platinum nanoparticles and cisplatin

Side effects and resistance of cancer cells to cisplatin are major drawbacks to its application, and recently, the possibility of replacing cisplatin with nanocompounds has been considered. Most chemotherapeutic agents are administered intravenously, and comparisons between the interactions of platinum nanoparticles (NP-Pt) and cisplatin with blood compartments are important for...

Analysis of the Cytotoxicity of Carbon-Based Nanoparticles, Diamond and Graphite, in Human Glioblastoma and Hepatoma Cell Lines

Nanoparticles have attracted a great deal of attention as carriers for drug delivery to cancer cells. However, reports on their potential cytotoxicity raise questions of their safety and this matter needs attentive consideration. In this paper, for the first time, the cytotoxic effects of two carbon based nanoparticles, diamond and graphite, on glioblastoma and hepatoma cells...

Interaction of graphene family materials with Listeria monocytogenes and Salmonella enterica

Graphene family materials have unique properties, which make them valuable for a range of applications. The antibacterial properties of graphene have been reported; however, findings have been contradictory. This study reports on the antimicrobial proprieties of three different graphene materials (pristine graphene (pG), graphene oxide (GO), and reduced graphene oxide (rGO...

Nanoparticles containing allotropes of carbon have genotoxic effects on glioblastomamultiforme cells

Nanoparticles containing allotropes of carbon have genotoxic effects on glioblastomamultiforme cells Mateusz Hinzmann,1 Slawomir Jaworski,1 Marta Kutwin,1 Joanna Jagiello,2 Rafal Kozinski,2 Mateusz Wierzbicki,1 Marta Grodzik,1 Ludwika Lipinska,2 Ewa Sawosz,1 Andrè Chwalibog31Division of Nanobiotechnology, Warsaw University of Life Sciences, 2Institute of Electronic Materials...

Carbon nanoparticles downregulate expression of basic fibroblast growth factor in the heart during embryogenesis

Carbon nanoparticles downregulate expression of basic fibroblast growth factor in the heart during embryogenesis Mateusz Wierzbicki,1 Ewa Sawosz,1 Marta Grodzik,1 Anna Hotowy,1 Marta Prasek,1 Slawomir Jaworski,1 Filip Sawosz,2 André Chwalibog2 1Division of Nanobiotechnology, Warsaw University of Life Sciences, Warsaw, Poland; 2Department of Veterinary Clinical and Animal Sciences...