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17 papers found.
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Impact of high- versus low-dose neuromuscular blocking agent administration on unplanned 30-day readmission rates in retroperitoneal laparoscopic surgery

acquisition: H. Keri Yang, Shuvayu S. Sen, Albert Dahan. Investigation: Chris Martini, Leon Aarts, Marieke Niesters, Albert Dahan. Methodology: Chris Martini, Michiel WarleÂ, Marieke Niesters, Albert Dahan ... dots are individual data. Boxes represent the median and interquartile range, whiskers the range, + the mean value. (TIFF) Author Contributions Conceptualization: Martijn Boon, Chris Martini, Shuvayu S

Cost-effectiveness of ceftolozane/tazobactam plus metronidazole versus piperacillin/tazobactam as initial empiric therapy for the treatment of complicated intra-abdominal infections based on pathogen distributions drawn from national surveillance data in the United States

The prevalence of antimicrobial resistance among gram-negative pathogens in complicated intra-abdominal infections (cIAIs) has increased. In the absence of timely information on the infecting pathogens and their susceptibilities, local or regional epidemiology may guide initial empirical therapy and reduce treatment failure, length of stay and mortality. The objective of this...

The impact of GI events on persistence and adherence to osteoporosis treatment: 3-, 6-, and 12-month findings in the MUSIC-OS study

to enrollment. Conflicts of interest A. Modi and S. Sen are employees of Merck & Co., Inc. and own stock in the company. J.D. Adachi has received grant support and speaker honorarium from Actavis

Impact of gastrointestinal events on patient-reported outcomes in Asia-Pacific women with osteoporosis: baseline results of the MUSIC OS-AP study

requirements. Conflict of interest A. Modi, XY, and S. Sen are employees of Merck & Co., Inc. A. Modi and S. Sen own stock in the company. S. Sajjan was an employee of Merck & Co., Inc. and owned stock in the

Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats

Vries, J. E. Oosterman, H. M. Eggink, P. de Goede, S. Sen, E. Foppen, O. Boudzovitch-Surovtseva. Methodology: S. E. laFleur, A. Kalsbeek. Project administration: E. M. de Vries. Resources: A. Boelen ... . Writing ± original draft: E. M. de Vries. 13 / 16 Writing ± review & editing: J. E. Oosterman, H. M. Eggink, P. de Goede, S. Sen, A. Boelen, J. A. Romijn, S. E. laFleur, A. Kalsbeek. 14 / 16 15 / 16 1

Association of gastrointestinal events with quality of life and treatment satisfaction in osteoporosis patients: results from the Medication Use Patterns, Treatment Satisfaction, and Inadequate Control of Osteoporosis Study (MUSIC OS)

. Modi and S. Sen are employees of Merck & Co., Inc. and own stock in the company. J.D. Adachi has received grant support and speaker honorarium from Actavis, Amgen, Eli Lilly, Merck & Co., Inc. and

Persistence with weekly and monthly bisphosphonates among postmenopausal women: analysis of a US pharmacy claims administrative database

Persistence with weekly and monthly bisphosphonates among postmenopausal women: analysis of a US pharmacy claims administrative database Tao Fan, Qiaoyi Zhang, Shuvayu S Sen Global Health Outcomes

Epidemiology of falls and osteoporotic fractures: a systematic review

Epidemiology of falls and osteoporotic fractures: a systematic review Alan Morrison,1 Tao Fan,2 Shuvayu S Sen,2 Lauren Weisenfluh11SCRIBCO, Effort, PA, 2Global Health Outcomes, Merck and Co, Inc

Gastrointestinal symptoms and association with medication use patterns, adherence, treatment satisfaction, quality of life, and resource use in osteoporosis: baseline results of the MUSIC-OS study

osteoporotic women. Compliance with ethical standards Conflicts of interest This study was funded by Merck & Co, Inc. A. Modi, S. Sen, A.M. Nguyen, S. Sajjan, and J. P. Weaver are employees of Merck & Co. and

Assessment of musculoskeletal abnormalities in children with mucopolysaccharidoses using pGALS

Background Children with mucopolysaccharidoses (MPS) often have musculoskeletal (MSK) abnormalities. Paediatric Gait, Arms, Legs, and Spine (pGALS), is a simple MSK assessment validated in school-age children to detect abnormal joints. We aimed to identify MSK abnormalities in children with MPS performing pGALS. Methods Videos of children with a spectrum of MPS performing pGALS...

Calcium and vitamin D intake by postmenopausal women with osteoporosis in Spain: an observational calcium and vitamin D intake (CaVIT) study

Calcium and vitamin D intake by postmenopausal women with osteoporosis in Spain: an observational calcium and vitamin D intake (CaVIT) study Tao Fan,1 Gonzalo Nocea,2 Ankita Modi,3 Leah Stokes,1 Shuvayu S Sen1 1Global Outcomes Research, Merck & Company, Whitehouse Station, NJ, USA; 2Department of Outcomes Research, Merck, Sharp and Dohme Spain, Madrid, Spain; 3Global Human Health...

Latest supernova data in the framework of the generalized Chaplygin gas model

We use the most recent Type Ia supernova data in order to study the dark energy–dark matter (XCDM) unification approach in the context of the generalized Chaplygin gas (GCG) model. Rather surprisingly, we find that data allow models with α > 1. We have studied how the GCG adjusts flat and non-flat models, and our results show that GCG is consistent with a flat case up to 68 per...

PDBe: Protein Data Bank in Europe

The Protein Data Bank in Europe (PDBe; pdbe.org) is a partner in the Worldwide PDB organization (wwPDB; wwpdb.org) and as such actively involved in managing the single global archive of biomacromolecular structure data, the PDB. In addition, PDBe develops tools, services and resources to make structure-related data more accessible to the biomedical community. Here we describe...

Rapid diagnosis of Indian visceral leishmaniasis using achatininH, a 9-O-acetylated sialic acid binding lectin.

We have developed a rapid, accurate, and inexpensive hemagglutination assay (HA) for diagnosis of Indian visceral leishmaniasis (VL) using achatininH, a 9-O-acetylated sialic acid binding lectin. The assay is based on the selective binding of achatininH to 9-O-acetylated derivatives of sialic acid (9-O-AcSA), which appears exclusively on the erythrocytes of patients with VL...

PDBe: Protein Data Bank in Europe

The Protein Data Bank in Europe (PDBe) (http://www.ebi.ac.uk/pdbe/) is actively working with its Worldwide Protein Data Bank partners to enhance the quality and consistency of the international archive of bio-macromolecular structure data, the Protein Data Bank (PDB). PDBe also works closely with its collaborators at the European Bioinformatics Institute and the scientific...

Hepatitis E virus infection in eastern India.

Most cases of enterically transmitted non-A, non-B hepatitis in India have so far been attributed to hepatitis E virus (HEV) infection. Most of the documented studies of hepatitis have focused on the incidence of this disease in northern, western, and south central India. A small seroprevalence study was conducted in the eastern Indian city of Patna to assess the degree of HEV...

Miscellaneous

Cancer Institute-Cairo University , Cairo, EGYPT 9 S. Koner, J. Basak, A. Chakraborty, D. Bhattacharya Majumder, S. Dasgupta, P. Das, N. Pal, S. Sen, S. Mukhopadhyay, A. Mukhopadhyay Molecular Biology