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Differences in Reporting of Analyses in Internal Company Documents Versus Published Trial Reports: Comparisons in Industry-Sponsored Trials in Off-Label Uses of Gabapentin

Using documents obtained through litigation, S. Swaroop Vedula and colleagues compared internal company documents regarding industry-sponsored trials of off-label uses of gabapentin with the ... -Label Uses of Gabapentin S. Swaroop Vedula 0 Tianjing Li 0 Kay Dickersin 0 Aaron S. Kesselheim, Harvard University, Brigham and Women's Hospital, United States of America 0 Department of Epidemiology

Analysis of the Structure of Surgical Activity for a Suturing and Knot-Tying Task

Background Surgical tasks are performed in a sequence of steps, and technical skill evaluation includes assessing task flow efficiency. Our objective was to describe differences in task flow for expert and novice surgeons for a basic surgical task. Methods We used a hierarchical semantic vocabulary to decompose and annotate maneuvers and gestures for 135 instances of a surgeon’s...

Who Has Used Internal Company Documents for Biomedical and Public Health Research and Where Did They Find Them?

Objective To describe the sources of internal company documents used in public health and healthcare research. Methods We searched PubMed and Embase for articles using internal company documents to address a research question about a health-related topic. Our primary interest was where authors obtained internal company documents for their research. We also extracted information...