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116 papers found.
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Effect of embedded nanoparticle surface chemistry on plasmonic organic photovoltaic devices

The effect of noble metal nanoparticle (NP) synthesis method on the plasmonic enhancement of organic photovoltaic device performance by these NPs is reviewed. For direct incorporation into a polymer fullerene bulk heterojunction (BHJ) active layer, chemically synthesized colloidal Au or Ag NPs with organic ligands are generally ineffective. Due to the tendency of the ligands in ...

Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype

work was supported by NIH grants R01 CA94233, STTR CA192646 and R01 FD04385 to D.L.D and by R01 HL 111169 to J.S.H. Author Contributions Conceptualization: Shweta Joshi, Alok R. Singh, Simon S. Wong ... , James S. Hagood, Donald L. Durden. Investigation: Shweta Joshi, James S. Hagood, Donald L. Durden. Methodology: Shweta Joshi, Alok R. Singh, Simon S. Wong, Muamera Zulcic, Min Jiang. Resources: Annie

Quantitative Viscosity Mapping Using Fluorescence Lifetime Measurements

Lubricant viscosity is a key driver in both the tribological performance and energy efficiency of a lubricated contact. Elastohydrodynamic (EHD) lubrication produces very high pressures and shear rates, conditions hard to replicate using conventional rheometry. In situ rheological measurements within a typical contact are therefore important to investigate how a fluid behaves under ...

Antimicrobial resistance in coagulase-positive staphylococci isolated from companion animals in Australia: A one year study

Methicillin-resistant coagulase-positive staphylococci (CoPS) have become increasingly recognised as opportunistic pathogens that limit therapeutic options in companion animals. The frequency of methicillin resistance amongst clinical isolates on an Australia-wide level is unknown. This study determined antimicrobial susceptibility patterns for CoPS isolated from clinical ...

Opportunities in the design and application of RNA for gene expression control

The past decade of synthetic biology research has witnessed numerous advances in the development of tools and frameworks for the design and characterization of biological systems. Researchers have focused on the use of RNA for gene expression control due to its versatility in sensing molecular ligands and the relative ease by which RNA can be modeled and designed compared to ...

Mentored peer review of standardized manuscripts as a teaching tool for residents: a pilot randomized controlled multi-center study

Background There is increasing need for peer reviewers as the scientific literature grows. Formal education in biostatistics and research methodology during residency training is lacking. In this pilot study, we addressed these issues by evaluating a novel method of teaching residents about biostatistics and research methodology using peer review of standardized manuscripts. We ...

The evolution of early childhood education policy in Hong Kong

Almost all 3- to 6-year-olds attend preschool programmes in Hong Kong; however, early childhood education (ECE) had been relatively neglected by the Hong Kong government until 2000 when the reform of school education system was initiated. Since then, notions of ‘child-centredness’ and holistic development have been promulgated as the core values of ECE. Against this backdrop, this ...

Transapical transcatheter aortic valve replacement in patients with or without prior coronary artery bypass graft operation

Background Transapical approach (TA) is an established access alternative to the transfemoral technique in patients undergoing transcatheter aortic valve replacement (TAVR) for treatment of symptomatic aortic valve stenosis. The impact of prior coronary artery bypass grafting (CABG) on clinical outcomes in patients undergoing TA-TAVR is not well defined. Methods A single center ...

Socioeconomic Determinants of Multimorbidity: A Population-Based Household Survey of Hong Kong Chinese

Introduction Multimorbidity has been well researched in terms of consequences and healthcare implications. Nevertheless, its risk factors and determinants, especially in the Asian context, remain understudied. We tested the hypothesis of a negative relationship between socioeconomic status and multimorbidity, with contextually different patterns from those observed in the West. ...

Zeaxanthin-independent energy quenching and alternative electron sinks cause a decoupling of the relationship between the photochemical reflectance index (PRI) and photosynthesis in an evergreen conifer during spring

In evergreen conifers, the winter down-regulation of photosynthesis and its recovery during spring are the result of a reorganization of the chloroplast and adjustments of energy-quenching mechanisms. These phenological changes may remain undetected by remote sensing, as conifers retain green foliage during periods of photosynthetic down-regulation. The aim was to assess if the ...

Reliability and Validity Study of Clinical Ultrasound Imaging on Lateral Curvature of Adolescent Idiopathic Scoliosis

Background Non-ionizing radiation imaging assessment has been advocated for the patients with adolescent idiopathic scoliosis (AIS). As one of the radiation-free methods, ultrasound imaging has gained growing attention in scoliosis assessment over the past decade. The center of laminae (COL) method has been proposed to measure the spinal curvature in the coronal plane of ultrasound ...

A Grape Seed Procyanidin Extract Ameliorates Fructose-Induced Hypertriglyceridemia in Rats via Enhanced Fecal Bile Acid and Cholesterol Excretion and Inhibition of Hepatic Lipogenesis

The objective of this study was to determine whether a grape seed procyanidin extract (GSPE) exerts a triglyceride-lowering effect in a hyperlipidemic state using the fructose-fed rat model and to elucidate the underlying molecular mechanisms. Rats were fed either a starch control diet or a diet containing 65% fructose for 8 weeks to induce hypertriglyceridemia. During the 9th week ...

A Rapid and Low-Cost PCR Thermal Cycler for Infectious Disease Diagnostics

]. While many well-characterized molecular assays have been developed around polymerase chain reaction (PCR) [ 5, 6 ], including pathogen and infectious disease detection Competing Interests: S. Wong is ... for providing the CDC DENV-1–4 RT-PCR Assay used in this manuscript. Author Contributions Conceived and designed the experiments: KC S. Wong. Performed the experiments: KC PW KW S. Wilson TW ZH S

Is Alcohol Use Disorder Identification Test (AUDIT) or Its Shorter Versions More Useful to Identify Risky Drinkers in a Chinese Population? A Diagnostic Study

Objective To examine the diagnostic performance of shorter versions of Alcohol Use Disorder Identification Test (AUDIT), including Alcohol Consumption (AUDIT-C), in identifying risky drinkers in primary care settings using conventional performance measures, supplemented by decision curve analysis and reclassification table. Study design and Setting A cross-sectional study of adult ...

Anonymous Three-Party Password-Authenticated Key Exchange Scheme for Telecare Medical Information Systems

Telecare Medical Information Systems (TMIS) provide an effective way to enhance the medical process between doctors, nurses and patients. For enhancing the security and privacy of TMIS, it is important while challenging to enhance the TMIS so that a patient and a doctor can perform mutual authentication and session key establishment using a third-party medical server while the ...

The Association of Types of Training and Practice Settings with Doctors’ Empathy and Patient Enablement among Patients with Chronic Illness in Hong Kong

Background The increase in non-communicable disease (NCD) is becoming a global health problem and there is an increasing need for primary care doctors to look after these patients although whether family doctors are adequately trained and prepared is unknown. Objective This study aimed to determine if doctors with family medicine (FM) training are associated with enhanced empathy ...

Gamma-Retrovirus Integration Marks Cell Type-Specific Cancer Genes: A Novel Profiling Tool in Cancer Genomics

Retroviruses have been foundational in cancer research since early studies identified proto-oncogenes as targets for insertional mutagenesis. Integration of murine gamma-retroviruses into the host genome favours promoters and enhancers and entails interaction of viral integrase with host BET/bromodomain factors. We report that this integration pattern is conserved in feline ...

Non-invasive molecular imaging of inflammatory macrophages in allograft rejection

Background Macrophages represent a critical cell type in host defense, development and homeostasis. The ability to image non-invasively pro-inflammatory macrophage infiltrate into a transplanted organ may provide an additional tool for the monitoring of the immune response of the recipient against the donor graft. We therefore decided to image in vivo sialoadhesin (Sn, Siglec 1 or ...

Primary Care Physicians’ Attitudes and Beliefs towards Chronic Low Back Pain: An Asian Study

Background Chronic low back pain is a serious global health problem. There is substantial evidence that physicians’ attitudes towards and beliefs about chronic low back pain can influence their subsequent management of the condition. Objectives (1) to evaluate the attitudes and beliefs towards chronic low back pain among primary care physicians in Asia; (2) to study the cultural ...