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31 papers found.
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The Association between Educational Level and Cardiovascular and Cerebrovascular Diseases within the EPICOR Study: New Evidence for an Old Inequality Problem

Background A consistent association has been reported between low socioeconomic status (SES) and cardiovascular events (CE), whereas the association between SES and cerebrovascular events (CBVD) is less clear. The aim of this study was to investigate the association between SES (measured using education) and CE/CBVD in a cohort study, as well as to investigate lifestyle and...

Micronutrients Involved in One-Carbon Metabolism and Risk of Breast Cancer Subtypes

Background Vitamins involved in one-carbon metabolism are hypothesized to influence breast cancer (BC) risk. However, epidemiologic studies that examined associations between B vitamin intake and BC risk have provided inconsistent results. We prospectively examined, in the Italian ORDET cohort, whether B vitamin consumption was associated with risk of BC and BC subtypes. Methods...

Osteoprotegerin and breast cancer risk by hormone receptor subtype: a nested case-control study in the EPIC cohort

Theron Johnson 0 Anne Tjønneland Anja Olsen Kim Overvad Aurélie Affret Mathilde His Marie-Christine Boutron-Ruault Heiner Boeing Antonia Trichopoulou Androniki Naska Philippos Orfanos Domenico Palli Sabina ... Sieri Amalia Mattiello Rosario Tumino Fulvio Ricceri H. Bas Bueno-de-Mesquita Petra H. M. Peeters Carla H. Van Gils Elisabete Weiderpass Eiliv Lund J. Ramón Quirós Antonio Agudo Maria-José Sánchez María

Dietary Total Antioxidant Capacity and Colorectal Cancer in the Italian EPIC Cohort

Background Colorectal cancer is the third most common cancer worldwide. Diet has been hypothesized as involved in colorectal cancer etiology, but few studies on the influence of total dietary antioxidant intake on colorectal cancer risk have been performed. Methods We investigated the association between colorectal cancer risk and the total antioxidant capacity (TAC) of the diet...

Metabolic Syndrome and Breast Cancer Risk: A Case-Cohort Study Nested in a Multicentre Italian Cohort

Background Metabolic syndrome (defined as at least three among abdominal obesity, high blood triglycerides, low high-density lipoprotein cholesterol, high blood glucose, and high blood pressure) is emerging as a risk factor for breast cancer; however few studies – most confined to postmenopausal women – have investigated associations between breast cancer risk and metabolic...

Espresso Coffee Consumption and Risk of Coronary Heart Disease in a Large Italian Cohort

Background The relationship between coffee consumption and coronary heart disease (CHD) has been investigated in several studies with discrepant results. We examined the association between Italian-style (espresso and mocha) coffee consumption and CHD risk. Methods We investigated 12,800 men and 30,449 women without history of cardiovascular disease recruited to the EPICOR...

Glycemic Index, Glycemic Load and Mammographic Breast Density: The EPIC Florence Longitudinal Study

A few studies have evaluated the association between diet and mammographic breast density (MBD) and results are inconsistent. MBD, a well-recognized risk factor for breast cancer, has been proposed as a marker of cumulative exposure to hormones and growth factors. Diets with a high glycemic index (GI) or glycemic load (GL) may increase breast cancer risk, via an effect on the...

Endogenous sex steroids in premenopausal women and risk of breast cancer: the ORDET cohort

Eva S Schernhammer 0 1 2 4 Francesca Sperati 8 Pedram Razavi 7 Claudia Agnoli 6 Sabina Sieri 6 Franco Berrino 5 Vittorio Krogh 6 Carlo Alberto Abbagnato 10 Sara Grioni 6 Giovanni Blandino 8 9 Holger

Reproductive factors and risk of mortality in the European Prospective Investigation into Cancer and Nutrition; a cohort study

. Katzke Heiner Boeing Antonia Trichopoulou Pagona Lagiou Dimitrios Trichopoulos Domenico Palli Sabina Sieri Rosario Tumino Carlotta Sacerdote Salvatore Panico H. Bas Bueno-de-Mesquita 0 Petra H. Peeters 0

Dietary Glycemic Load and Glycemic Index and Risk of Cerebrovascular Disease in the EPICOR Cohort

Background Studies on the association of stroke risk to dietary glycemic index (GI) and glycemic load (GL) have produced contrasting results. Objective To investigate the relation of dietary GI and GL to stroke risk in the large EPIC-Italy cohort (EPICOR) recruited from widely dispersed geographic areas of Italy. Design We studied 44099 participants (13,646 men and 30,453 women...

The mediterranean dietary pattern and breast cancer risk in Greek-Cypriot women: a case-control study

Background Diet has long been suspected to impact on breast cancer risk. In this study we evaluated whether the degree of adherence to a Mediterranean diet pattern modifies breast cancer risk amongst Greek-Cypriot women. Methods Subjects included 935 cases and 817 controls, all participating in the MASTOS case-control study in Cyprus. The study was approved by the Cyprus National...

A prospective study of dietary selenium intake and risk of type 2 diabetes

Background Growing evidence raises concern about possible associations of high selenium exposure with diabetes in selenium-replete populations such as the US. In countries with lower selenium status, such as Italy, there is little epidemiological evidence on the association between selenium and diabetes. This study examined the prospective association between dietary selenium...

Dietary intakes in infertile women a pilot study

Background The reproductive axis is closely linked to nutritional status. The purpose of this study was to compare the nutritional status in two groups of young infertile women, without clinically overt eating disorders: hypothalamic amenorrhea (HA) and polycystic ovary syndrome (PCOS). Methods Eighteen young infertile women (10 HA, 8 PCOS) attending an outpatient gynecological...

Understanding the Links among neuromedin U Gene, beta2-adrenoceptor Gene and Bone Health: An Observational Study in European Children

Neuromedin U, encoded by the NMU gene, is a hypothalamic neuropeptide that regulates both energy metabolism and bone mass. The beta-2 adrenergic receptor, encoded by the ADRB2 gene, mediates several effects of catecholamine hormones and neurotransmitters in bone. We investigated whether NMU single nucleotide polymorphisms (SNPs) and haplotypes, as well as functional ADRB2 SNPs...

Circulating Biomarkers of One-Carbon Metabolism in Relation to Renal Cell Carcinoma Incidence and Survival

Background The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.

Methylome Analysis and Epigenetic Changes Associated with Menarcheal Age

Drogan Heiner Boeing Rudolf Kaaks Angela Risch Dimitrios Trichopoulos Pagona Lagiou Giovanna Masala Sabina Sieri Rosario Tumino Salvatore Panico J. Ramo n Quiro s Mara-Jose Sa nchez Perez Pilar Amiano Jose

Urinary 6-Sulfatoxymelatonin Levels and Risk of Breast Cancer in Postmenopausal Women

Background Low urinary melatonin levels have been associated with an increased risk of breast cancer in premenopausal women. However, the association between melatonin levels and breast cancer risk in postmenopausal women remains unclear.

Dietary Fat Intake and Development of Specific Breast Cancer Subtypes

IRCCS Istituto Nazionale dei Tumori , Via Venezian 1, I-20133 Milan , Italy ( 2 Sabina Sieri , Paolo Chiodini, Claudia Agnoli, Valeria Pala, Franco Berrino, Antonia Trichopoulou, Vassiliki Benetou, Effie

Fruit and Vegetable Intake and Risk of Breast Cancer by Hormone Receptor Status

Background Estrogen receptor–negative (ER−) breast cancer has few known or modifiable risk factors. Because ER− tumors account for only 15% to 20% of breast cancers, large pooled analyses are necessary to evaluate precisely the suspected inverse association between fruit and vegetable intake and risk of ER− breast cancer.

Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study

Birgit Teucher 0 Heiner Boeing Krasimira Aleksandrova Antonia Trichopoulou Pagona Lagiou Dimitrios Trichopoulos Domenico Palli Sabina Sieri Salvatore Panico Rosario Tumino Paolo Vineis Jos Ramn Quirs