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5 papers found.
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Efficacy and tolerability of rivastigmine patch therapy in patients with mild-to-moderate Alzheimer’s dementia associated with minimal and moderate ischemic white matter hyperintensities: A multicenter prospective open-label clinical trial

, Heeyoung Kang, Oh Dae Kwon, SangYun Kim, Jae-Hyeok Lee, Eun Joo Chung, Sang-Won Park, Mee Young Park, Bora Yoon, Byeong C. Kim, Sang Won Seo, Seong Hye Formal analysis: Kyung Won Park. Funding acquisition ... , Heeyoung Kang, Oh Dae Kwon, SangYun Kim, Jae-Hyeok Lee, Eun Joo Chung, Sang-Won Park, Mee Young Park, Bora Yoon, Byeong C. Kim, Sang Won Seo, Seong Hye Choi. Methodology: Kyung Won Park, Byeong C. Kim

Electronic Alerts with Automated Consultations Promote Appropriate Antimicrobial Prescriptions

Background To promote appropriate antimicrobial use in bloodstream infections (BSIs), we initiated an intervention program consisting of electronic alerts and automated infectious diseases consultations in which the identification and antimicrobial susceptibility test (ID/AST) results were reported. Methods We compared the appropriateness of antimicrobial prescriptions and clinical ...

Urbanization of Scrub Typhus Disease in South Korea

Background Scrub typhus is an endemic disease in Asia. It has been a rural disease, but indigenous urban cases have been observed in Seoul, South Korea. Urban scrub typhus may have a significant impact because of the large population. Methods Indigenous urban scrub typhus was epidemiologically identified in Seoul, the largest metropolitan city in South Korea, using national ...

The Heme Oxygenase-1 Inducer THI-56 Negatively Regulates iNOS Expression and HMGB1 Release in LPS-Activated RAW 264.7 Cells and CLP-Induced Septic Mice

The nuclear DNA binding protein high mobility group box 1 (HMGB1) has recently been suggested to act as a late mediator of septic shock. The effect of ((S)-6,7-dihydroxy-1-(4-hydroxynaphthylmethyl)-1,2,3,4-tetrahydroisoquinoline alkaloid, also known as THI-56, in an experimental model of sepsis was investigated. THI-56 exhibited potent anti-inflammatory properties in response to ...

DNA Repair in Human Pluripotent Stem Cells Is Distinct from That in Non-Pluripotent Human Cells

The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also carries the risk of added genomic instability. Genomic instability is most often linked to DNA repair deficiencies, which indicates that screening/characterization of possible repair deficiencies in pluripotent human stem ...