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Search: authors:"Sara Pratesi"

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Angiogenic T cell expansion correlates with severity of peripheral vascular damage in systemic sclerosis

studies are required to clarify the function of Tang cells and investigate the mechanisms responsible for their change in SSc. Author Contributions Conceptualization: Mirko Manetti, Sara Pratesi, Enrico ... Maggi, Marco Matucci-Cerinic. Data curation: Mirko Manetti, Sara Pratesi, Eloisa Romano, Irene Rosa, Lidia Ibba-Manneschi, Marco Matucci-Cerinic. Formal analysis: Mirko Manetti, Sara Pratesi, Eloisa

How the immune system responds to therapeutic biological agents

Biological agents target disease mechanisms and have modified the natural history of several immune-mediated disorders. Biological agents are structurally immunogenic, and therefore usually elicit a minor, subclinical and transient phenomenon. Occasionally, however, these drugs induce complete cellular and humoral immune responses, with the main clinical consequences being ...