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Multigenerational effects of bisphenol A or ethinyl estradiol exposure on F2 California mice (Peromyscus californicus) pup vocalizations

Patterson for constructing the soundproof boxes. Author Contributions Conceptualization: Sarah A. Johnson, Frauke Hoffmann, A. Katrin Schenk, Cheryl S. Rosenfeld. Formal analysis: Sarah A. Johnson ... , Cheryl S. Rosenfeld. Funding acquisition: Cheryl S. Rosenfeld. Investigation: Sarah A. Johnson, Michelle J. Farrington, Claire R. Murphy, Paul D. Caldo, Leif A. McAllister, Sarabjit Kaur, Catherine Chun

Effects of Obesity on Bone Mass and Quality in Ovariectomized Female Zucker Rats

Obesity and osteoporosis are two chronic conditions that have been increasing in prevalence. Despite prior data supporting the positive relationship between body weight and bone mineral density (BMD), recent findings show excess body weight to be detrimental to bone mass, strength, and quality. To evaluate whether obesity would further exacerbate the effects of ovariectomy on...

Disruption of Parenting Behaviors in California Mice, a Monogamous Rodent Species, by Endocrine Disrupting Chemicals

The nature and extent of care received by an infant can affect social, emotional and cognitive development, features that endure into adulthood. Here we employed the monogamous, California mouse (Peromyscus californicus), a species, like the human, where both parents invest in offspring care, to determine whether early exposure to endocrine disrupting chemicals (EDC: bisphenol A...

Interactions between Parents and Parents and Pups in the Monogamous California Mouse (Peromyscus californicus)

The California mouse (Peromyscus californicus) may be a valuable animal model to study parenting as it is one of the few monogamous and biparental rodent species. By using automated infra-red imaging and video documentation of established pairs spanning two days prior to birth of the litter until d 5 of post natal development (PND), it was possible to follow interactions between...

Effects of Vitamin E on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats

The present study examined the dose-dependent effect of vitamin E in reversing bone loss in ovariectomized (Ovx) rats. Sprague-Dawley rats were either Sham-operated (Sham) or Ovx and fed control diet for 120 days to lose bone. Subsequently, rats were divided into 5 groups (/group): Sham, Ovx-control, low dose (Ovx