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To Test or to Treat? An Analysis of Influenza Testing and Antiviral Treatment Strategies Using Economic Computer Modeling

Background Due to the unpredictable burden of pandemic influenza, the best strategy to manage testing, such as rapid or polymerase chain reaction (PCR), and antiviral medications for patients who present with influenza-like illness (ILI) is unknown. Methodology/Principal Findings We developed a set of computer simulation models to evaluate the potential economic value of seven...

Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania

Background During the 2009 H1N1 influenza epidemic, policy makers debated over whether, when, and how long to close schools. While closing schools could have reduced influenza transmission thereby preventing cases, deaths, and health care costs, it may also have incurred substantial costs from increased childcare needs and lost productivity by teachers and other school employees...

Would school closure for the 2009 H1N1 influenza epidemic have been worth the cost?: a computational simulation of Pennsylvania

Pittsburgh, 130 Desoto St, Pittsburgh, PA, 15261, USAShawn T Brown, Julie HY Tai, Rachel R Bailey, Margaret A Potter, Ronald E Voorhees, Megan LeJeune, John J Grefenstette, Donald S Burke, Sarah M McGlone ... , USAJulie HY Tai, Rachel R Bailey, Megan LeJeune, Sarah M McGlone & Bruce Y LeeAllegheny County Health Department, Pittsburgh, PA, USARonald E VoorheesTepper School of Business, Carnegie Mellon University