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Search: authors:"Sebastiano Biondo"

5 papers found.
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Large differences in global transcriptional regulatory programs of normal and tumor colon cells

Background Dysregulation of transcriptional programs leads to cell malfunctioning and can have an impact in cancer development. Our study aims to characterize global differences between transcriptional regulatory programs of normal and tumor cells of the colon. Methods Affymetrix Human Genome U219 expression arrays were used to assess gene expression in 100 samples of colon tumor...

Phase II study of preoperative bevacizumab, capecitabine and radiotherapy for resectable locally-advanced rectal cancer

Biondo 5 Ramon Salazar 1 0 Department of Medical Oncology, Hospital General de L'Hospitalet , Barcelona , Spain 1 Department of Medical Oncology, Institut Catala d'Oncologia-IDIBELL, L'Hospitalet

A randomized phase II study of capecitabine-based chemoradiation with or without bevacizumab in resectable locally advanced rectal cancer: clinical and biological features

Alonso 9 Pilar Escudero 3 Javier Gallego 11 Javier Sastre Cristina Grvalos Sebastiano Biondo Amalia Palacios Enrique Aranda 10 0 Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute

Clinical Value of Prognosis Gene Expression Signatures in Colorectal Cancer: A Systematic Review

Introduction The traditional staging system is inadequate to identify those patients with stage II colorectal cancer (CRC) at high risk of recurrence or with stage III CRC at low risk. A number of gene expression signatures to predict CRC prognosis have been proposed, but none is routinely used in the clinic. The aim of this work was to assess the prediction ability and potential...