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Role of Duodenogastroesophageal Reflux in the Pathogenesis of Esophageal Mucosal Injury and Gastroesophageal Reflux Symptoms

Can J Gastroenterol Role of duodenogastroesophageal reflux in the pathogenesis of esophageal mucosal injury and gastroesophageal reflux symptoms Xiao-rong Xu Zhao-shen Li Duo-wu Zou Guo-ming Xu MSc

Correction to: Guiding the Training of Distributed Text Representation with Supervised Weighting Scheme for Sentiment Analysis

In the originally published article, the acknowledgment section is missing. Please find it as follows.

Guiding the Training of Distributed Text Representation with Supervised Weighting Scheme for Sentiment Analysis

With the rapid growth of social media, sentiment analysis has received growing attention from both academic and industrial fields. One line of researches for sentiment analysis is to feed bag-of-words (BOW) text representation into classifiers. Usually, raw BOW requires weighting schemes to obtain better performance, where important words are given more weights while unimportant...

Speed-consistency Based Safety Evaluation for Freeway Diverging Segments

Diverging segments are potential bottlenecks because of frequent lane change and deceleration maneuvers. Speed study has been proven to be an effective way to understand the safety performance of diverging segments. This paper addresses the safety level of diverging segments in terms of speed consistency. Speed data is extracted by Tracker based on aerial video imager collected...

Sequential Differentiation of Embryonic Stem Cells into Neural Epithelial-Like Stem Cells and Oligodendrocyte Progenitor Cells

Background Recent advances in stem cell technology afford an unlimited source of neural progenitors and glial cells for cell based therapy in central nervous system (CNS) disorders. However, current differentiation strategies still need to be improved due to time-consuming processes, poorly defined culture conditions, and low yield of target cell populations. Methodology...

Rabbit Model of Human Gliomas: Implications for Intra-Arterial Drug Delivery

The prognosis for malignant brain tumors remains poor despite a combination of surgery, radiotherapy, and chemotherapy. This is partly due to the blood-brain barrier, a major obstacle that prevents therapeutic agents from effectively reaching the tumor. We have recently developed a method for precise and predictable opening of the blood-brain barrier via the intra-arterial...

Prevention of Esophageal Strictures After Endoscopic Submucosal Dissection: A Promising Therapy Using Carboxymethyl Cellulose Sheets

Gastroenterology, Raja Perempuan 2 Hospital , 1328 Taman Tengku Ahmad Panglima, 15350 Kota Bharu, Kelantan , Malaysia 3 Zhao Shen Li Background Esophageal stricture is one of the serious adverse events following

Rectally administered indomethacin to prevent post-ESWL-pancreatitis (RIPEP): study protocol for a randomized controlled trial

Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is the first-line therapy for large pancreatic duct stones. Although it is a highly effective and safe procedure for the fragmentation of pancreatic stones, it is still not complication-free. Just like endoscopic retrograde cholangiopancreatography (ERCP), pancreatitis is the most common complication. To date, nonsteroidal...

Cap-assisted hemoclip application with forward-viewing endoscope for hemorrhage induced by endoscopic sphincterotomy: a prospective case series study

Guang-Yong Wang 1 Zhao-Shen Li 0 0 Department of Gastroenterology, Changhai Hospital, Second Military Medical University , 168 Changhai Road, Shanghai 200433 , China 1 Department of Gastroenterology, 411

Aurora kinase-A overexpression in mouse mammary epithelium induces mammary adenocarcinomas harboring genetic alterations shared with human breast cancer

Recent data from The Cancer Genome Atlas analysis have revealed that Aurora kinase A (AURKA) amplification and overexpression characterize a distinct subset of human tumors across multiple cancer types. Although elevated expression of AURKA has been shown to induce oncogenic phenotypes in cells in vitro, findings from transgenic mouse models of Aurora-A overexpression in mammary...

The Types Division and Severity Threshold of Traffic Conflict on Freeway Interchange

This paper selects time to collision (TTC) as the traffic conflict index. Shooting high-definition video from high altitude above freeway interchange by unmanned aircraft, the TTC was calculated by processing software. The mechanism of traffic conflict on Freeway Interchange area was researched by combining subjective and objective method, and then defined severity. Firstly...

Fat Intake Is Not Linked to Prostate Cancer: A Systematic Review and Dose-Response Meta-Analysis

Background Since the late 1960s, the average global supply of fat has increased by 20 g per capita per day. While fat intake has been considered a potential risk factor for prostate cancer (Pca), the hypothesis from previous epidemiologic studies remained equivocal. Materials and Methods Relevant cohort studies were identified through a literature search in PubMed, ScienceDirect...

Comparative Analyses of Lipoprotein Lipase, Hepatic Lipase, and Endothelial Lipase, and Their Binding Properties with Known Inhibitors

The triglyceride lipase gene subfamily plays a central role in lipid and lipoprotein metabolism. There are three members of this subfamily: lipoprotein lipase, hepatic lipase, and endothelial lipase. Although these lipases are implicated in the pathophysiology of hyperlipidemia and atherosclerosis, their structures have not been fully solved. In the current study, we established...

Is Acupuncture Effective for Hypertension? A Systematic Review and Meta-Analysis

Objective To determine the efficacy of acupuncture for hypertension. Method Seven electronic databases were searched on April 13, 2014 to include eligible randomized controlled trials (RCTs). Data were extracted and risk of bias was assessed. Subgroup analyses and meta- analysis were performed. Results 23 RCTs involving 1788 patients were included. Most trials had an unclear risk...

An Improved Liquid Chromatography–Tandem Mass Spectrometric Method to Quantify Formoterol in Human Urine

Formoterol is a new threshold substance in the prohibited list 2012 according to World Anti-Doping Agency. Extracted by ethyl acetate using formoterol-D6 as internal standard, formoterol underwent a constant flow rate gradient elution separation in reversed-phase liquid chromatography. Subsequently, mass spectrometry analysis was conducted by tandem mass spectrometry in the...

Infarction of the Corpus Callosum: A Retrospective Clinical Investigation

Objectives The aim of this study was to investigate patients with ischemic infarctions in the territory of the corpus callosum to advance our understanding of this rare stroke subtype by providing comprehensive descriptive and epidemiological data. Methods From January 1, 2010 to June 30, 2014, all cases of acute ischemic stroke diagnosed by clinical manifestation and diffusion...

Virus propagation power of the dynamic network

With the development of mobile networks, propagation characteristics and defense mechanism of the virus have attracted increasing research attention. But current researches are mainly concerned with static network topology or community structure and some studies focus on characteristics of virus and malware. Little attention is paid to the influence of dynamic changes of network...

Bisphenol A Exposure Enhances Atherosclerosis in WHHL Rabbits

Bisphenol A (BPA) is an environmental endocrine disrupter. Excess exposure to BPA may increase susceptibility to many metabolic disorders, but it is unclear whether BPA exposure has any adverse effects on the development of atherosclerosis. To determine whether there are such effects, we investigated the response of Watanabe heritable hyperlipidemic (WHHL) rabbits to 400-µg/kg...

LAPTM4B-35, a Cancer-Related Gene, Is Associated with Poor Prognosis in TNM Stages I-III Gastric Cancer Patients

Background Lysosome-associated transmembrane protein 4β-35 (LAPTM4B-35), a member of the mammalian 4-tetratransmembrane spanning protein superfamily, has been reported to be overexpressed in several cancers. However the expression of LAPTM4B-35 and its role in the progression of gastric cancer (GC) remains unknown. The aim of this study was to investigate LAPTM4B-35 expression in...

Silencing Herpes Simplex Virus Type 1 Capsid Protein Encoding Genes by siRNA: A Promising Antiviral Therapeutic Approach

Herpes simplex virus type 1 (HSV-1), a member of the herpesviridae, causes a variety of human viral diseases globally. Although a series of antiviral drugs are available for the treatment of infection and suppression of dissemination, HSV-1 remains highly prevalent worldwide. Therefore, the development of novel antiviral agents with different mechanisms of action is a matter of...