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ObjectiveStenotrophomonas maltophilia is a Gram-negative bacterium commonly isolated from nosocomial infections. Analysis of the genome of the clinical S. maltophilia isolate K279a indicates that it encodes a diffusible signal factor (DSF)-dependent cell–cell signaling mechanism that is highly similar to the system previously described in phytopathogens from the genera...
bacterial transcriptional regulator YipR Shi-qi An ORCID: orcid.org/0000-0002-2593-96421,2, Miguel A. Valvano2, Yan-hua Yu3, Jeremy S. Webb1 & Guillermo Lopez Campos2 BMC Microbiology volume 20, Article ... approved the manuscript. Corresponding author Correspondence to Shi-qi An. Ethics declarations Ethics approval and consent to participate Not applicable. Consent for publication Not applicable
Stenotrophomonas maltophilia is an antibiotic-resistant Gram-negative pathogen, which is associated with hospital-acquired infection. The genome encodes a protein highly related to the Ax21 protein of Xanthomonas oryzae that is implicated in interactions of this plant pathogen with rice. Here, we report on the pleiotropic nature of ax21 mutation in S. maltophilia and the effects...
Wan-Ying Zhong 0 Yu-Wei Liang 0 Jin-Yang Liu Yun-Shi Zhong 3 Shi-Qi An 4 Hongzhou Gu Ji-Liang Tang 0 State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of
Many pathogenic bacteria use cell–cell signaling systems involving the synthesis and perception of diffusible signal molecules to control virulence as a response to cell density or confinement to niches. Bacteria produce signals of diverse structural classes. Signal molecules of the diffusible signal factor (DSF) family are cis-2-unsaturated fatty acids. The paradigm is cis-11...
Bis-(3′,5′) cyclic di-guanylate (cyclic di-GMP) is a key bacterial second messenger that is implicated in the regulation of many critical processes that include motility, biofilm formation and virulence. Cyclic di-GMP influences diverse functions through interaction with a range of effectors. Our knowledge of these effectors and their different regulatory actions is far from...
Biofilm formation and dispersal in the black rot pathogen Xanthomonas campestris pathovar campestris (Xcc) is influenced by a number of factors. The extracellular mannanase ManA has been implicated in biofilm dispersal whereas biofilm formation requires a putative glycosyl transferase encoded by the xag gene cluster. Previously we demonstrated that the post-transcriptional...
Chronic polymicrobial infections of the lung are the foremost cause of morbidity and mortality in cystic fibrosis (CF) patients. The composition of the microbial flora of the airway alters considerably during infection, particularly during patient exacerbation. An understanding of which organisms are growing, their environment and their behaviour in the airway is of importance...
