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Search: authors:"Shingo Maegawa"

6 papers found.
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Highly sensitive avoidance plays a key role in sensory adaptation to deep-sea hydrothermal vent environments

crews and staff of RV Natsushima and ROV Hyper-Dolphin during cruise NT12-10. Conceptualization: Tetsuya Ogino, Shingo Maegawa, Shuichi Shigeno, Haruhiko Toyohara. Data curation: Tetsuya Ogino, Shingo ... Maegawa. Formal analysis: Tetsuya Ogino, Shingo Maegawa. Funding acquisition: Tetsuya Ogino, Haruhiko Toyohara. Investigation: Tetsuya Ogino, Shingo Maegawa, Haruhiko Toyohara. Methodology: Tetsuya

Correct anteroposterior patterning of the zebrafish neurectoderm in the absence of the early dorsal organizer

Background The embryonic organizer (i.e., Spemann organizer) has a pivotal role in the establishment of the dorsoventral (DV) axis through the coordination of BMP signaling. However, as impaired organizer function also results in anterior and posterior truncations, it is of interest to determine if proper anteroposterior (AP) pattern can be obtained even in the absence of early...

Cooling-Sensitive TRPM8 Is Thermostat of Skin Temperature against Cooling

We have shown that cutaneous cooling-sensitive receptors can work as thermostats of skin temperature against cooling. However, molecule of the thermostat is not known. Here, we studied whether cooling-sensitive TRPM8 channels act as thermostats. TRPM8 in HEK293 cells generated output (y) when temperature (T) was below threshold of 28.4°C. Output (y) is given by two equations: At...

FGF signaling is required for β-catenin-mediated induction of the zebrafish organizer

Shingo Maegawa 0 Mt Varga 0 Eric S. Weinberg 0 0 Department of Biology, University of Pennsylvania , Goddard Labs 316, Philadelphia, PA 19104-6017 , USA We have used the maternal effect mutant